Abstract: The invention relates to 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: A method for manufacturing a material strand assembly for a vehicle. The method includes: extruding strand material in an extruder so that an extruded material strand is produced; monitoring the quality of the extruded material strand so as to detect faults of the extruded material strand; in case of a detection of a fault, cutting out the fault from the material strand and re-joining cutting end faces, thus producing a joint, so that a faultless material strand is produced. The cutting-out step is conducted such that any two adjacent joints are at a minimum joint distance from each other. The faultless material strand is stored in a storage unit so as to produce the material strand assembly. The extruded material strand is passed through a first strand accumulator between the extruder and the cutting arrangement and through a second strand accumulator between the cutting arrangement and the storage unit.

Abstract: The invention relates to 1,3-diaza-spiro-[3.4]-octane derivatives, their preparation and use in medicine, particularly in various neurological disorders, including but not limited to pain, neurodegenerative disorders, neuroinflammatory disorders, neuropsychiatric disorders, substance abuse/dependence.

Abstract: A method for controlling a gas supply to a process chamber is provided. The method includes: measuring a gas parameter by each of two or more sensors provided in the process chamber; determining a combined gas parameter from the measured gas parameters; and controlling the gas supply to the process chamber based on the determined combined gas parameter.

Abstract: The invention relates to 3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: The invention relates to a conveyor line (1) for the continuous production of drywall boards as well as a slurry distributing device (22) which is used in this conveyor line (1). The distributing device is used for the uniform and low-speed flow distribution of slurries (20).

Abstract: The invention relates to 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: The invention relates to 8-amino-2-oxo-1,3-diaza-spiro[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: The invention relates to 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: A process is provided for the making of estetrol starting from a 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one, wherein A is an C1-C5 alkyl group, preferably a methyl group, or a C7-C12 benzylic group, preferably a benzyl group. This process is particularly suitable to industry.

Abstract: The invention relates to 3-((hetero-)aryl)-8-amino-2-oxo-1,3 -diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Abstract: A spray head for suppling at least one die of a forming machine with lubricating coolant, said forming machine comprising a lower die and an upper die, is preferably produced by rapid manufacturing and is designed as a single piece to a large extent. The use of rapid manufacturing allows the production of the most varied configurations, such as stabilizing honey-comb structures or drip points, which allow a more advantageous design of the spray head.

Abstract: Water refilling plug for automatically filling and refilling the cells of a battery, comprising a valve body which is operated by a float and which closes the valve when the battery cell is full in order to terminate the refilling operation, wherein there is a permanent-magnet force between the valve body and the float, the movement of the float being transmitted to the valve body by said permanent-magnet force.

Abstract: A process is provided for the making of estetrol starting from a 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one, wherein A is an C1-C5 alkyl group, preferably a methyl group, or a C7-C12 benzylic group, preferably a benzyl group. This process is particularly suitable to industry.

Abstract: In one embodiment an optoelectronic system can include a photonics interposer having a substrate and a functional interposer structure formed on the substrate, a plurality of through vias carrying electrical signals extending through the substrate and the functional interposer structure, and a plurality of wires carrying signals to different areas of the functional interposer structure. The system can further include one or more photonics device integrally formed in the functional interposer structure, and one or more prefabricated component attached to the functional interposer structure.

Abstract: A method for controlling a gas supply to a process chamber is provided. The method includes: measuring a gas parameter by each of two or more sensors provided in the process chamber; determining a combined gas parameter from the measured gas parameters; and controlling the gas supply to the process chamber based on the determined combined gas parameter.

Abstract: A method and a device for operating a waste heat utilization device for an internal combustion engine of a motor vehicle is disclosed. The waste heat utilization device contains a waste heat utilization circuit in which a working medium circulates. A conveyor, an evaporator, an expansion machine, and a condenser are disposed in the waste heat utilization circuit. A basic adjustment of the waste heat utilization circuit is provided, which as a function of a heat input into the working medium adjusts the mass flow rate at the conveyor and/or the ratio between high pressure and low pressure at the expansion machine. In addition, a pilot control is provided which recognizes a change of the operating point of the internal combustion engine and, when the operating point is changed, controls the condensation output of the condenser in accordance with a mass distribution of the working medium in the waste heat utilization circuit optimized to the new operating point.