Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: The present invention features novel methods for the cryopreservation of mammalian cell that combine the advantages of the slow-freezing and vitrification approaches while avoiding their shortcomings. Generally, the methods include the use of a capillary tube made of a thermally conductive wall material and a thin wall such that the ratio of the thermal conductivity of the wall material to the wall thickness is at least 1,000-500,000. The solution is then exposed to temperatures equal to or less than ?80° C. and the vitrification solution containing the mammalian cells is cooled at a rate equal to or greater than 30,000-100,000,000° C./minute. The exposure of the capillary tube with a thermally conductive and thin wall allows for vitrification of the solution in the absence of ice formation. Cryoprotectants can also be added to the vitrification solution to further prevent ice formation.

Abstract: Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Systems and methods for determining an extended low contrast detectability performance function for an operating range for a core operating mode of a radiographic imaging system using actual reconstructed images characterize the contrast performance of a radiographic imaging system over its operating range and for any patient size based on the off-line calibration, uses ordered pairs of flux index and contrast index for each scanned object to provide a contrast index for each protocol for each contrast set, and uses the ordered pairs of flux index and contrast index to determine an extended low contrast detectability performance function for the operating range of a radiographic imaging system. Extended low contrast detectability performance data compilation and methods of clinical use, and low contrast phantom configurations and methods of calibration are also disclosed.

Abstract: Evaluating dose performance of a radiographic imaging system with respect to image quality using a phantom, a channelized hotelling observer module as a model observer, and a printer, a plaque, or an electronic display includes scanning and producing images for a plurality of sections of the phantom using the radiographic imaging system, wherein the plurality of sections represent a range of patient sizes and doses and wherein the sections of the phantom contain objects of measurable detectability. Also included is analyzing the images to determine detectability results for one or more of the contained objects within the images of the plurality of sections of the phantom, wherein the analyzing includes using a channelized hotelling observer (CHO) module as a model observer; and displaying, via the printer, the plaque, or the electronic display, a continuous detectability performance measurement function using the determined detectability results.

Abstract: Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller. The controller is configured to apply a first kVp for a first time period, apply a second kVp for a second time period, integrate two or more view datasets during the first time period, integrate one or more view datasets during the second time period, and generate an image using the datasets integrated during the first time period and during the second time period.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller. The controller is configured to apply a first kVp for a first time period, apply a second kVp for a second time period, integrate two or more view datasets during the first time period, integrate one or more view datasets during the second time period, and generate an image using the datasets integrated during the first time period and during the second time period.

Abstract: Systems and methods for determining an extended low contrast detectability performance function for an operating range for a core operating mode of a radiographic imaging system using actual reconstructed images characterize the contrast performance of a radiographic imaging system over its operating range and for any patient size based on the off-line calibration, uses ordered pairs of flux index and contrast index for each scanned object to provide a contrast index for each protocol for each contrast set, and uses the ordered pairs of flux index and contrast index to determine an extended low contrast detectability performance function for the operating range of a radiographic imaging system. Extended low contrast detectability performance data compilation and methods of clinical use, and low contrast phantom configurations and methods of calibration are also disclosed.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to apply a first kVp for a first time period, apply a second kVp for a second time period, wherein the second time period is different from the first time period, acquire a first asymmetric view dataset during at least a portion of the first time period, acquire a second asymmetric view dataset during at least a portion of the second time period, and generate an image using the acquired first and second asymmetric view datasets.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to obtain kVp projection data at a first kVp, obtain kVp projection data at a second kVp, extract data from the kVp projection data obtained at the second kVp, add the extracted data to the kVp projection data obtained at the first kVp to generate mitigated projection data at the first kVp, and generate an image using the mitigated projection data at the first kVp and using the projection data obtained at the second kVp.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to obtain kVp projection data at a first kVp, obtain kVp projection data at a second kVp, extract data from the kVp projection data obtained at the second kVp, add the extracted data to the kVp projection data obtained at the first kVp to generate mitigated projection data at the first kVp, and generate an image using the mitigated projection data at the first kVp and using the projection data obtained at the second kVp.