Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to apply a first kVp for a first time period, apply a second kVp for a second time period, wherein the second time period is different from the first time period, acquire a first asymmetric view dataset during at least a portion of the first time period, acquire a second asymmetric view dataset during at least a portion of the second time period, and generate an image using the acquired first and second asymmetric view datasets.

Abstract: The present invention is directed to a method and apparatus of multi-energy data acquisition. An imaging system is also provided and includes a number of HF electromagnetic energy filters. The filters include at least a first and a second filter wherein the first filter is positioned in a path of HF electromagnetic energy when an HF electromagnetic energy source is energized to a first voltage and the second filter is positioned in the path of HF electromagnetic energy when the HF electromagnetic energy source is energized to a second voltage.

Abstract: The present invention is directed to a method and apparatus of multi-energy data acquisition. An imaging system is also provided and includes a number of HF electromagnetic energy filters. The filters include at least a first and a second filter wherein the first filter is positioned in a path of HF electromagnetic energy when an HF electromagnetic energy source is energized to a first voltage and the second filter is positioned in the path of HF electromagnetic energy when the HF electromagnetic energy source is energized to a second voltage.

Abstract: The present invention is directed to a method and apparatus of multi-energy data acquisition. An imaging system is also provided and includes a number of HF electromagnetic energy filters. The filters include at least a first and a second filter wherein the first filter is positioned in a path of HF electromagnetic energy when an HF electromagnetic energy source is energized to a first voltage and the second filter is positioned in the path of HF electromagnetic energy when the HF electromagnetic energy source is energized to a second voltage.

Abstract: The present invention features novel methods for the cryopreservation of mammalian cell that combine the advantages of the slow-freezing and vitrification approaches while avoiding their shortcomings. Generally, the methods include the use of a capillary tube made of a thermally conductive wall material and a thin wall such that the ratio of the thermal conductivity of the wall material to the wall thickness is at least 1,000-500,000. The solution is then exposed to temperatures equal to or less than ?80° C. and the vitrification solution containing the mammalian cells is cooled at a rate equal to or greater than 30,000-100,000,000° C./minute. The exposure of the capillary tube with a thermally conductive and thin wall allows for vitrification of the solution in the absence of ice formation. Cryoprotectants can also be added to the vitrification solution to further prevent ice formation.

Abstract: A method and apparatus for tailoring the profile of an x-ray beam for radiographic imaging for a specific subject is disclosed. The invention includes a filter assembly having a pair of filters, each of which may be dynamically controlled by a motor assembly during data acquisition. The filters are positionable in the x-ray beam so as to shape the intensity profile of the x-ray beam. In one exemplary embodiment, the filters are dynamically positioned during CT data acquisition based on the shape of the subject. A method of determining the shape of the subject prior to CT data acquisition is also disclosed.

Abstract: The present invention is directed to a networked scanner environment wherein each scanner is communicatable with one or more databases configured to store data associated with previously executed imaging sessions. The one or more databases may be queried by a user to determine, based on a set of user inputs, an historical evaluation of the prior imaging sessions conducted in accordance with scan parameters similar to the scan parameters of an imminent imaging session. The present invention includes a global database that is accessible by a series of remotely located imaging systems as well as includes one or more databases particular to a specific treatment facility housing one or more imaging scanners. The present invention is also applicable with a stand-alone imaging system having a database local to that particular imaging system for storing and accessing data associated with imaging sessions conducted on that particular imaging system.

Abstract: An apparatus and process for determining and displaying an artifact index (AI) to a system operator are provided. The AI is determined by acquiring and processing imaging data of a phantom. The AI is then displayed to the operator on a console so that the operator may, if necessary, reset the scanning parameters or select a new scanning protocol that will result in a reconstructed image of a subject having reduced artifact presence. By providing a likelihood of artifact presence to the system operator, the present invention eliminates the need for the operator to recall those scanning profiles that are susceptible to high artifact presence.

Abstract: A method of manufacturing a collimator mandrel having variable attenuation characteristics is presented. The manufacturing process includes the placement of a layer of attenuating material on a core of base material. The layer of attenuating material is relatively thin and varies in thickness circumferentially around the core. The collimator mandrel may be manufactured by placing a cast about a core of non-attenuating material, filling a void between the cast and the core with an attenuating material, allowing the material to cure, and removing the cast from the assembly.

Abstract: A system and method of diagnostic imaging is provided that includes positioning a subject in an imaging device, collecting positioning information of the subject from at least one sensor disposed in proximity of the imaging device, and determining a relative position of the subject within the imaging device from at least the position information. The present invention automatically selects a proper attenuation filter configuration, corrects patient centering, and corrects noise prediction errors, thereby increasing dose efficiency and tube output.

Abstract: A method of manufacturing a collimator mandrel having variable attenuation characteristics is presented. The manufacturing process includes the placement of a layer of attenuating material on a core of base material. The layer of attenuating material is relatively thin and varies in thickness circumferentially around the core. The collimator mandrel may be manufactured by placing a cast about a core of non-attenuating material, filling a void between the cast and the core with an attenuating material, allowing the material to cure, and removing the cast from the assembly.

Abstract: A method and apparatus for tailoring the profile of an x-ray beam for radiographic imaging for a specific subject is disclosed. The invention includes a filter assembly having a pair of filters, each of which may be dynamically controlled by a motor assembly during data acquisition. The filters are positionable in the x-ray beam so as to shape the intensity profile of the x-ray beam. In one exemplary embodiment, the filters are dynamically positioned during CT data acquisition based on the shape of the subject. A method of determining the shape of the subject prior to CT data acquisition is also disclosed.

Abstract: The present invention is directed to a networked scanner environment wherein each scanner is communicatable with one or more databases configured to store data associated with previously executed imaging sessions. The one or more databases may be queried by a user to determine, based on a set of user inputs, an historical evaluation of the prior imaging sessions conducted in accordance with scan parameters similar to the scan parameters of an imminent imaging session. The present invention includes a global database that is accessible by a series of remotely located imaging systems as well as includes one or more databases particular to a specific treatment facility housing one or more imaging scanners. The present invention is also applicable with a stand-alone imaging system having a database local to that particular imaging system for storing and accessing data associated with imaging sessions conducted on that particular imaging system.

Abstract: The present invention is directed to a method and apparatus of objectively testing the low contrast performance of an imaging system. Images of a uniform phantom and images of a low contrast detectability phantom are reconstructed. Thereafter, a group of pixels from an image of the uniform phantom are removed and replaced with a group of pixels from an image of the LCD phantom. A user or test observer is then prompted to identify which quadrant of the first phantom image contains a group of pixels from the LCD phantom. An accuracy of a user response is then determined and conveyed to the user. The present invention is applicable with a number of imaging modalities including computer tomography, magnetic resonance imaging, PET, ultrasound, and the like.

Abstract: A method and apparatus for tailoring the profile of an x-ray beam for radiographic imaging for a specific subject is disclosed. The invention includes a filter assembly having a pair of filters, each of which may be dynamically controlled by a motor assembly during data acquisition. The filters are positionable in the x-ray beam so as to shape the intensity profile of the x-ray beam. In one exemplary embodiment, the filters are dynamically positioned during CT data acquisition based on the shape of the subject. A method of determining the shape of the subject prior to CT data acquisition is also disclosed.

Abstract: A system and method of diagnostic imaging is provided that includes determining a position of a subject in a scanning bay and tailoring x-ray attenuation such that the specific position of the subject is taken into consideration. The present invention automatically selects a proper attenuation filter configuration, corrects patient centering, and corrects noise prediction errors, thereby increasing dose efficiency and tube output.

Abstract: A system and method of diagnostic imaging is provided that includes positioning a subject in a scanning bay, comparing a center of mass of the subject to a reference point, and repositioning the subject in the scanning bay to reduce a difference in position between the center of mass of the subject and the reference point. The present invention automatically selects a proper attenuation filter configuration, corrects patient centering, and corrects noise prediction errors, thereby increasing dose efficiency and tube output.

Abstract: A method for reconstructing an image of an object utilizing a computed tomographic (CT) imaging system having a radiation source configured to project a beam of radiation through an object and towards a multislice detector array configured to sense attenuation of the radiation passing through the object; the method includes helically scanning an object to acquire a plurality of slices of projection data, generating a separate projection dataset for each of N separate detector rows wherein the separate projection datasets include detector row projection data and detector row conjugate projection data, combining the detector row projection data and the detector row conjugate projection data, and helically weighting the combined projection data using a combined helical weighting and conjugate data weighting algorithm such that a greater weight is applied to combined center row projection data than to at least one outermost detector row projection data.

Abstract: The present invention includes a filtering apparatus for a CT imaging system or equivalently for an x-ray imaging system. The filtering apparatus may be translated along a first axis or a transverse axis to with respect to an attenuation pattern of a subject during an imaging session to reduce radiation exposure to anatomical regions of the subject sensitive to radiation exposure and/or regions from which data is not being acquired.

Abstract: A method and apparatus is disclosed to acquire scout scan data of a subject and analyzed to determine a peak-to-peak modulation amplitude of a normalized waveform indicative of subject size and shape. The scout scan data provides a representation of patient size and shape that is associated with an ideal tube current modulation waveform or profile. The ideal tube current modulation profile may then be sampled or approximated at various points to determine a tube current modulation profile for implementation to acquire CT data with reduced dose but without sacrificing image quality.