Patents by Inventor Thomas Meade

Thomas Meade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100004177
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
    Type: Application
    Filed: September 3, 2009
    Publication date: January 7, 2010
    Applicant: Dow AgroSciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy Denver Hey, Robin Leola Thompson, Thomas Meade, Ze-Sheng Li, Sean Michael Russell, Joel Jay Sheets, Justin Michael Lira, Kristin Julee Fencil, Jon Christopher Mitchell
  • Publication number: 20090325892
    Abstract: Synergistic pesticidal mixtures are provided.
    Type: Application
    Filed: May 1, 2008
    Publication date: December 31, 2009
    Applicant: Dow AgroSciences LLC
    Inventors: Jim X. Huang, Jonathan M. Babcock, Thomas Meade, Marc Farrow
  • Patent number: 7605228
    Abstract: The subject invention relates to insecticidal toxin complex (“TC”) fusion proteins and to polynucleotides that encode these fusion proteins. In some embodiments, the invention provide a fusion protein comprising a Class A protein, a Class B protein, and a Class C TC protein fused together to form a single protein. In some other embodiments, the invention provides a fusion protein compromising a Class B and a Class C TC proteins fused together. In the latter embodiments, the BC and CB fusion protein can be used to enhance or potentate the anti-insect activity of a “Toxin A” or Class A protein. The subject invention also includes plants, cells (bacterial and plant cells for example) and seeds that comprise the polynueleotides. The subject invention also includes methods of controlling pests (preferably insects and other plant pests) with fusion proteins of the subject invention.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: October 20, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Timothy Denver Hey, Thomas Meade, Stephanie Love Burton, Donald Joseph Merlo, Qihua Cai, Haley Jo Moon, Joel Jay Sheets, Aaron Todd Woosley
  • Patent number: 7585944
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: September 8, 2009
    Assignee: Dow Agrosciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy D. Hey, Joel J. Sheets, Thomas Meade, Ze-Sheng Li, Justin M. Lira, Sean M. Russell, Robin L. Thompson, Jon C. Mitchell, Kristin Fencil
  • Publication number: 20090221501
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Application
    Filed: February 16, 2009
    Publication date: September 3, 2009
    Applicant: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Mitchell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Patent number: 7491698
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: February 17, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Mitchell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Publication number: 20080311096
    Abstract: Compositions for controlling lepidopteran insects use Cry1Fa and Cry1Ab core toxin containing proteins in combination to delay or prevent development of resistance.
    Type: Application
    Filed: June 2, 2008
    Publication date: December 18, 2008
    Inventors: Bruce A. Lang, James W. Bing, Jonathan M. Babcock, Thomas Meade, Nicholas P. Storer, Blair David Siegfried, Elisen Jose Guedes Pereira
  • Publication number: 20080108665
    Abstract: Methods to control certain invertebrates including insects in agricultural, urban, animal health, and industrial systems by directly or systemically applying to a locus where control is desired an effective amount of a compound of N-substituted sulfoximines.
    Type: Application
    Filed: February 9, 2007
    Publication date: May 8, 2008
    Inventors: Jim X. Huang, Yuanming Zhu, Richard B. Rogers, Michael R. Loso, Robert L. Hill, James D. Thomas, Thomas Meade, James M. Gifford, Joseph J. DeMark, Benjamin M. Nugent
  • Patent number: 7354568
    Abstract: The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: April 8, 2008
    Assignee: California Institute of Technology
    Inventors: Thomas Meade, Scott Fraser, Russell Jacobs
  • Publication number: 20080058248
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
    Type: Application
    Filed: September 18, 2007
    Publication date: March 6, 2008
    Applicant: Dow AgroSciences LLC
    Inventors: Patricia Apel-Birkhold, Timothy Hey, Robin Thompson, Thomas Meade, Ze-Sheng Li, Sean Russell, Joel Sheets, Justin Lira, Kristin Fencil, Jon Mitchell
  • Publication number: 20070299264
    Abstract: N-Substituted sulfoximines are effective at controlling insects resistant to common insecticides.
    Type: Application
    Filed: February 9, 2007
    Publication date: December 27, 2007
    Inventors: Jim X. Huang, Richard B. Rogers, Nailah Orr, Thomas C. Sparks, James M. Gifford, Michael R. Loso, Yuanming Zhu, Thomas Meade
  • Patent number: 7285632
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins encoded by genes from Xenorhabdus bovienii strain ILM 104, and methods of controlling an insect with the toxin proteins.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: October 23, 2007
    Assignee: Dow AgroSciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy Denver Hey, Robin Leola Thompson, Thomas Meade, Ze-Sheng Li, Sean Michael Russell, Joel Jay Sheets, Justin Michael Lira, Kristin Julee Fencil, Jon Christopher Mitchell
  • Publication number: 20070006340
    Abstract: Compositions for controlling lepidopteran insects use Cry1Fa and Cry1Ab core toxin containing proteins in combination to delay or prevent development of resistance.
    Type: Application
    Filed: March 4, 2005
    Publication date: January 4, 2007
    Inventors: Bruce Lang, James Bing, Jonathan Babcock, Thomas Meade, Nicholas Storer, Blair Siegfried, Elisen Guedes Pereire
  • Publication number: 20060211016
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Application
    Filed: January 30, 2006
    Publication date: September 21, 2006
    Inventors: Jon Kayyem, Stephen O'Connor, Michael Gozin, Changjun Yu, Thomas Meade
  • Publication number: 20060205653
    Abstract: The subject invention provides exciting new sources for surprising, new types of toxin complex (“TC”) proteins. The subject invention includes these new classes and types of TC proteins. The subject invention also includes polynucleotides that encode the subject proteins. The subject invention further provides vectors and cells comprising these polynucleotides. The subject invention also provides novel methods of controlling insects. The subject invention relates in part to the surprising discovery that new types of TC proteins can be obtained from a widely diverse phylogenetic spectrum of organisms including, most notably and surprisingly, eukaryotic fungus.
    Type: Application
    Filed: March 2, 2006
    Publication date: September 14, 2006
    Inventors: Ignacio Larrinua, Aaron Woosley, Thomas Meade, Donald Merlo, Timothy Hey, Stephanie Burton
  • Publication number: 20060168683
    Abstract: The subject invention relates to insecticidal toxin complex (“TC”) fusion proteins and to polynucleotides that encode these fusion proteins. The subject invention also includes polynucleotides that encode the subject TC fusion proteins, and vectors comprising said polynucleotides. In some embodiments, the invention provides a fusion protein comprising a Class A protein, a Class B protein, and a Class C TC protein fused together to form a single protein. In some other embodiments, the invention provides a fusion protein comprising a Class B and a Class C TC proteins fused together. In the latter embodiments, the BC or CB fusion protein can be used to enhance or potentiate the anti-insect activity of a “Toxin A” or Class A protein. Heretofore, there was no expectation that such fusion proteins would properly function and retain their activity when fused together. The subject invention advantageously reduces the number of genes needed to transform plants.
    Type: Application
    Filed: March 2, 2005
    Publication date: July 27, 2006
    Applicant: Dow AgroSciences LLC
    Inventors: Timothy Hey, Thomas Meade, Stephanie Burton, Donald Merlo, Qihua Cai, Haley Moon, Joel Sheets, Aaron Woosley
  • Publication number: 20060099631
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Application
    Filed: December 6, 2005
    Publication date: May 11, 2006
    Inventors: Jon Kayyem, Stephen O'Conner, Michael Gozin, Changjun Yu, Thomas Meade
  • Publication number: 20060088475
    Abstract: The present invention relates to magnetic resonance imaging (MRI) contrast agent. In particular, the present invention provides MRI contrast agents that are sensitive to the enzyme beta-glucoronidase. The MRI contrast agents provide compositions and methods for non-invasive diagnostic imaging of tissues, including necrotic tumors.
    Type: Application
    Filed: May 10, 2005
    Publication date: April 27, 2006
    Applicant: Northwestern University
    Inventors: Joseph Duimstra, Thomas Meade
  • Publication number: 20060073532
    Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, ?, of an electron transfer process.
    Type: Application
    Filed: November 18, 2005
    Publication date: April 6, 2006
    Inventor: Thomas Meade
  • Publication number: 20060003382
    Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, ?, of an electron transfer process. In particular, the present invention provides probes of the outer-sphere environment of a redox center and methods of correlating changes in electrochemical properties to characterize the same.
    Type: Application
    Filed: May 10, 2005
    Publication date: January 5, 2006
    Inventors: Amanda Eckermann, Kylie Barker, Thomas Meade