Abstract: A connector arrangement comprising a connector and a cable connected to the connector, each comprising at least one conductor pair for transmitting a differential signal, wherein the cable comprises a first portion and a second portion, in which the conductor pair comprises electric contacts, and wherein the conductors are at a first mutual distance in the first portion and a second mutual distance in the second portion, the second mutual distance being greater than the first distance, wherein an intermediate portion is formed between the first portion and the second portion, in which intermediate portion the distance between the conductors of a conductor pair increases in the direction of an interface-side end of the connector, wherein the conductor pair is guided in an unshielded cable in the first portion, and wherein the conductors are surrounded by an external conductor in at least one part of the intermediate portion.

Abstract: A connecting device for pipelines or hose lines with a threaded body and with a pipe-like end piece which can be inserted into a receptacle formed on the threaded body and which can be fitted therein by means of a swivel nut screwed onto the threaded body, wherein the receptacle of the threaded body has the shape of a widening cone and the circumferential surface of the end piece that engages in the receptacle has a conical design, is characterized in that the circumferential surface (12) of the threaded body (10) that bears the external thread (30) has, in the direction of the front end of said surface, an inclined profile directed opposite to the cone of the receptacle (11), and the swivel nut (17) has, with its surface (18) bearing the internal thread (31), a profile complementary thereto, and the external thread (30) and internal thread (31) are designed as tapered threads in such a way that a radial force emanating from the tapered thread with the swivel nut (17) screwed on is directed opposite to the ra

Abstract: The invention relates to an electrical connector assembly, comprising an electrical connector and a cable connected to the electrical connector, which each have at least one conductor pair for transferring a differential signal, wherein the cable has a first section and the electrical connector has a second section, in which second section the conductor pair has plug contacts, and wherein the conductors have a first mutual distance (X) in the first section and a second mutual distance (Y) in the second section, which second mutual distance is greater than the first distance, wherein an intermediate section, in which the distance of the conductors of a conductor pair increases toward a plugging end of the electrical connector, is formed between the first section and the second section, wherein the conductor pair is surrounded by a conductor pair shield in the first section and/or in the second section, which conductor pair shield shields the conductor pair from external electromagnetic influences, and wherein

Abstract: Provided is a method for control and/or monitoring and/or optimization of a chromatographic process, in which the method comprises at least 2 columns which are operated, alternatingly, wherein this operation can be carried out in that the at least 2 columns are operated in interconnected and disconnected states, wherein the columns switch positions after such a sequence of interconnected and disconnected state, and wherein downstream of at least one, or of each column, a detector is located capable of detecting the desired product and/or impurities when passing the detector.

Abstract: The present invention relates to a process for the production of ammonium perrhenate (APR), which includes the use of Ca(OH)2 and to ammonium perrhenate which can be obtained by the method according to the invention.

Abstract: A fluid-operated braking system (1) for a tractor-trailer vehicle includes a trailer control valve (2), a parking brake module (3), and an electronic control unit (4) electrically connected to the trailer control valve (2) and to the parking brake module (3). A pressure fluid accumulator (13) of the braking system (1) is connected to a control pressure input (P43) of the trailer control valve (2). A redundancy circuit controls the control pressure input (P43), even during a malfunction of the control unit (4). The parking brake module (3) includes a control valve (14), a redundancy valve (15) and a changeover valve (16) controlled by an electronic switch unit (20) with a holding function. When the control unit (4) malfunctions, the last error-free switching position of the control valve (14) or the redundancy valve is maintained until a operationally safe resting state is reached or the ignition system is switched off.

Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.

Abstract: The present application relates to novel (imidazo[1,2-a]pyridin-3-yl)methyl-substituted diazaheterobicyclic compounds, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apnoea and central sleep apnoea and snoring. The present application further relates to a method of discovering a compound having TASK-1-and/or TASK-3-blocking properties.

Abstract: A dental material dispensing device has a plunger means which for dispensing the dental material is movable for urging at least one component of a dental material toward a dispensing area. The device further has cure control means with an energy source and a flow path on which the dental composition and/or the dental material flows past the energy source during dispensation. The device is operable for exposing the dental composition and/or the dental material to a specific energy by control of the energy source and/or by control of the speed of the flow of the dental composition and/or the dental material on the flow path. The device is configured for dispensing a coherent strand of dental material in a dispensing cycle. The device is further configured for operating in a first dispensing mode and additionally in a second dispensing mode during the same dispensing cycle. The ratio between the specific energy in the second dispensing mode and the specific energy in the first dispensing mode is smaller than 1.

Abstract: A component for an exhaust system of an internal combustion engine includes a component housing (22) elongated in the direction of a housing axis with an exhaust gas inlet (21) and with an exhaust gas outlet (24) and a carrier assembly unit (28) for connecting the component (16) to a carrier structure. The carrier assembly unit (28) includes a carrier rod (46), the carrier rod (46) being fixed to the component housing (22) in at least two fastening areas (60, 62) located at spaced locations from one another along the carrier rod (46). The carrier assembly unit (28) has at least one carrier rod connection area (52, 54) for connection to the carrier structure.

Abstract: A child seat for mounting on a motor vehicle seat is comprised of at least one contact surface device for a child accommodated in the child seat, the contact surface device having at least a first section and a second section, the second section being transferable relative to the first section from a first position to a second position by the action of an at least partially outwardly directed force acting on the second section to damp deceleration of the child in the case of a displacement of the child towards the second section.

Abstract: A securing apparatus for securing a valve lever in a set position comprises a base body; a sliding piece; and a screw element, wherein the base body and the sliding piece each have a clamping surface; wherein the sliding piece is displaceably supported at the base body along a longitudinal axis; and wherein the screw element is rotatably supported at the base body and has a thread that is in engagement with a mating thread of the sliding piece so that a position of the sliding piece relative to the base body along the longitudinal axis is restricted to a maximum spacing between the clamping surfaces that can be changed by a rotation of the screw element in order to clamp the valve lever between the clamping surfaces.

Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: A method for monitoring, evaluating and controlling a cyclic chromatographic purification process that involves at least two adsorbers. According to the method, one step is monitoring of the chromatogram, including the measurement of at least one current concentration-proportional signal in the liquid. Another step is conducting an evaluation of the chromatogram, including a comparison of at least one of the current concentration-proportional signals measured in the monitoring step with a threshold value thereof. A further step is controlling the chromatographic purification process by adapting the termination of the currently running phase as a function of the comparison of the evaluation step and initiating the next phase. Finally, according to the method, the sequence of steps is carried out in given order at least twice.

Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: According to one implementation, a system includes a computing platform having a hardware processor and a system memory storing a software code including multiple artificial neural networks (ANNs). The hardware processor executes the software code to partition a multi-dimensional input vector into a first vector data and a second vector data, and to transform the second vector data using a first piecewise-polynomial transformation parameterized by one of the ANNs, based on the first vector data, to produce a transformed second vector data. The hardware processor further executes the software code to transform the first vector data using a second piecewise-polynomial transformation parameterized by another of the ANNs, based on the transformed second vector data, to produce a transformed first vector data, and to determine a multi-dimensional output vector based on an output from the plurality of ANNs.

Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.

Abstract: The present application relates to novel 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.

Abstract: An adjuvant combination composed of a milling assistant and a concrete admixture for a composition including cement, for accelerating cement hydration, wherein the milling assistant includes at least one amino alcohol and at least one cement hydration accelerator selected from chlorides, thiocyanates, nitrates, nitrites and hydroxides, and the concrete admixture includes a reaction product of at least one calcium compound with at least one silicon compound selected from a silicon dioxide compound, a silica compound and a silicate compound. Using the adjuvant combination produces a significant acceleration in the hardening of a composition including cement, after the addition of water. This is an advantage especially in the production of prefabricated concrete components, allowing quicker deshuttering.

Abstract: A device for controlling a fluid flow in an array of fluid pathways on a microfluidic chip is provided. The device comprising: two or more resistors provided upstream of the chip wherein each upstream resistor is configured to provide a resistance at an upstream end of a fluid pathway; two or more resistors provided downstream of the chip wherein each downstream resistor is configured to provide a resistance at a downstream end of a fluid pathway, wherein the values of the resistances are selected in order to control a proportion of fluid that flows through each fluid pathway.