Abstract: A screw for use in joining workpieces, for example automotive body parts, is provided that includes a head portion, an externally threaded shank extending from the head portion, a flow-hole-forming tip disposed at a distal end portion of the externally threaded shank, and a recessed spring washer disposed under the head portion. The recessed spring washer is configured to apply a clamping load to joined workpieces as they expand and contract.

Abstract: An assembly is provided that includes a castellated upper substrate defining a plurality of alternating troughs and ridges. A lower substrate is disposed adjacent the upper castellated substrate, and an adhesive material is disposed between the castellated upper substrate and the lower substrate. A fastener extends through a trough of the castellated upper substrate, through the adhesive material, and into the lower substrate. A method of assembling the upper and lower substrates is also provided, which includes plastically deforming the castellated upper substrate to reduce an intake of air between the substrates.

Abstract: Systems and methods for reducing or eliminating corrosion in joined materials are disclosed, for example, multi-material joints. The system may include a sealing device including a body and a tip. The tip may be configured to form a seal around a local region of a material having a fastener disposed therein. The sealing device may be configured to apply a sealant material from the tip to the local region and form a cap thereover. The tip of the sealing device may form a cavity between the material and the inner surface of the tip, which may be filled with the sealant material to form the cap. In one embodiment, the sealing device may be configured to couple to the joining device that inserted the fastener. This may allow for accurate and robust placement of the sealant material directly after the fastener is inserted.

Abstract: An incremental forming machine and a process are disclosed that comprise selecting a blank and selecting a stylus that has a tip at one end. The stylus may be heated to a desired temperature before contacting the blank with the stylus to change a characteristic of the blank or part. The stylus apparatus may include a tip on an end of a shaft and a resistance heating element disposed inside the tip. Alternatively, the stylus apparatus may include an induction heating coil disposed around the tip. The tip of the stylus may have a rotatable ball that engages the blank or part.

Abstract: A screw for use in joining workpieces, for example automotive body parts, is provided that includes a head portion, an externally threaded shank extending from the head portion, a flow-hole-forming tip disposed at a distal end portion of the externally threaded shank, and a recessed spring washer disposed under the head portion. The recessed spring washer is configured to apply a clamping load to joined workpieces as they expand and contract.

Abstract: A fastener for use in joining workpieces, for example automotive body parts such as a roof to a body frame member, is provided that includes a plastically deformable head portion, a platform disposed at a bottom of the head portion, and a distal end portion extending from the platform and defining at least one of elastically deformable locking member. The head portion is heat staked to one workpiece, and the elastically deformable locking member engages another workpiece to secure the workpieces together. The platform provides spacing, or a bond gap in one form, between the workpieces, and a material and geometry of the fastener are configured to compensate for a difference in thermal expansion of the workpieces.

Abstract: A coffee pod is described with an improved sealing surface for a filter disposed within the pod. The improved sealing surface provides better adherence between the filter and a sidewall of the pod so that unadhered portions are minimized and operation is improved. A coffee pod is also described with an improved foot structure having a configuration and thickness designed to minimize buckling while also utilizing a cost-efficient amount of material.

Abstract: A method of joining a first panel and a second panel with an adhesive and flow drill screws is provided. The adhesive is applied in a continuous strip and the flow drill screws are inserted through the first panel, the continuous strip of adhesive, and through a second panel. Material displaced by the flow drill screw forms a collar. An intermediate portion of the collar defines a bond gap for the adhesive between the panels. An assembly is made according to the method includes the intermediate collar portion formed by the flow drill screw displacing material from the panels that sets a bond gap between the first and second panels for the adhesive.

Abstract: Joints and methods of forming the same are disclosed. The joint may include a first component including an indentation formed therein having a width, a second component, an adhesive layer disposed between the first and second components, and a fastener extending through the indentation. The fastener may join the first and second components and have a head with a width greater than a minimum width of the indentation. The method may include forming an indentation having a width in a first component, applying an adhesive to one of multiple components, and stacking the components. The indentation may form a bond gap between two components. A fastener may be inserted having a head with a width greater than the width of the indentation into the indentation to join the components. The indentation may space the components apart to provide a larger bond gap for the adhesive.

Abstract: Joints and methods of forming the same are disclosed. The joint may include a first component including an indentation formed therein having a width, a second component, an adhesive layer disposed between the first and second components, and a fastener extending through the indentation. The fastener may join the first and second components and have a head with a width greater than a minimum width of the indentation. The method may include forming an indentation having a width in a first component, applying an adhesive to one of multiple components, and stacking the components. The indentation may form a bond gap between two components. A fastener may be inserted having a head with a width greater than the width of the indentation into the indentation to join the components. The indentation may space the components apart to provide a larger bond gap for the adhesive.

Abstract: Disclosed herein are humanized anti-LGR5 antibodies for the treatment of cancer. Antibodies disclosed herein may bind LGR5 without disrupting LGR5-RSPO1 binding or signaling, and may disrupt LGR5 signaling through Wnt that is independent of RSPO1. Also disclosed are heavy and light chain polypeptide sequences for the biding of LGR5, for example without disrupting LGR5-RSPO binding or signaling.

Abstract: A method of reducing the cycle time required for flow-drill screw operations by providing a dimple on a part that is engaged by a flow-drill screw. A tip of the flow-drill screw engages a contact band at a location spaced from the tip of the distal end of the flow-drill screw and base portion of the dimple. Friction between the flow-drill screw tip and dimple creates a heat concentration area and results in displaced material forming a threaded sleeve. The flow-drill screw is secured by the threads of the threaded sleeve to secure the top part to the bottom part.

Abstract: Disclosed herein are humanized anti-LGR5 antibodies for the treatment of cancer. Antibodies disclosed herein may bind LGR5 without disrupting LGR5-RSPO1 binding or signaling, and may disrupt LGR5 signaling through Wnt that is independent of RSPO1. Also disclosed are heavy and light chain polypeptide sequences for the biding of LGR5, for example without disrupting LGR5-RSPO binding or signaling.

Abstract: A beverage preparation machine of the type which uses pre-packaged containers of beverage ingredients is described. The beverage preparation machine is configured for controlling the volume of air resident in at least a part of a delivery system of the machine to produce predetermined characteristics in a prepared beverage.

Abstract: Method of preparing beverages using a beverage preparation machines and in particular a beverage preparation machine of the type which uses pre-packaged containers of beverage ingredients. The method includes controlling the volume of air resident in at least a part of a delivery system of the machine to produce predetermined characteristics in a prepared beverage.

Abstract: Disclosed herein are humanized anti-LGR5 antibodies for the treatment of cancer. Antibodies disclosed herein may bind LGR5 without disrupting LGR5-RSPO1 binding or signaling, and may disrupt LGR5 signaling through Wnt that is independent of RSPO1. Also disclosed are heavy and light chain polypeptide sequences for the biding of LGR5, for example without disrupting LGR5-RSPO binding or signaling.

Abstract: Methods and apparatus for detecting a swarm attack based on a plurality of convergence hypotheses related to correlated movements of entities in an area of interest. Projected tracks for the entities are determined based on position reports received for the entities. At least one of the convergence hypotheses are updated based, at least in part on the projected tracks and a convergence hypotheses is output when a score assigned to the hypothesis exceeds a threshold value.

Abstract: A vehicle interior structure includes a main body, a first side trim panel and a top finisher panel. The main body has a first side defining a plurality of first side attachment portions. The first side trim panel at least partially covers the first side of the main body and has a plurality of first panel attachment portions attached to the first side attachment portions of the main body. The first side trim panel also includes at least one first projection spaced apart from the first panel attachment portions and located adjacent to the upper end of the main body, the at least one first projection having an aperture. The top finisher panel covers the upper end of the main body and has at least one downwardly extending second projection that extends into the aperture of the at least one first projection retaining the first side trim panel in position.