Patents by Inventor Thomas O. Daniel

Thomas O. Daniel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
    Patent number: 10047151
    Abstract: Uses of the protein cereblon as a predictor of clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: August 14, 2018
    Assignee: CELGENE CORPORATION
    Inventors: Antonia Lopez-Girona, Peter H. Schafer, Anita Gandhi, Derek Mendy, Thomas O. Daniel
  • METHODS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES USING CEREBLON AS A PREDICTOR
    Publication number: 20160319005
    Abstract: Uses of the protein cereblon as a predictor of clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Application
    Filed: May 9, 2016
    Publication date: November 3, 2016
    Inventors: Antonia Lopez-Girona, Peter H. Schafer, Anita Gandhi, Derek Mendy, Thomas O. Daniel
  • Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
    Patent number: 9365640
    Abstract: Uses of the protein cereblon as a predictor of clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: June 14, 2016
    Assignee: CELGENE CORPORATION
    Inventors: Antonia Lopez-Girona, Peter H. Schafer, Anita Gandhi, Derek Mendy, Thomas O. Daniel
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 9260472
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: February 16, 2016
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. Dimarchi, Anna-Maria A. Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Antigen-binding polypeptides and their uses
    Patent number: 9175083
    Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 3, 2015
    Assignee: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Troy E. Wilson, Thomas P. Cujec, Feng Tian, Anna-Maria A. Hays, Bruce E. Kimmel, Lillian Ho
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 8906676
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: December 9, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human four helical bundle polypeptides and their uses
    Patent number: 8907064
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 9, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20140296145
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: April 2, 2014
    Publication date: October 2, 2014
    Applicant: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard DiMarchi, Anna-Maria Hays Putnam, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • Human growth hormone modified at position 35
    Patent number: 8778880
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: July 15, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • METHODS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES USING CEREBLON AS A PREDICTOR
    Publication number: 20120322073
    Abstract: Uses of the protein cereblon as a predictor of clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Application
    Filed: April 27, 2012
    Publication date: December 20, 2012
    Inventors: Antonia Lopez-Girona, Peter H. Schafer, Anita Gandhi, Derek Mendy, Thomas O. Daniel
  • Modified human interferon polypeptides and their uses
    Patent number: 8232371
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 31, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria A. Hays Putnam, Troy E. Wilson
  • MODIFIED HUMAN INTERFERON POLYPEPTIDES AND THEIR USES
    Publication number: 20120142896
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Application
    Filed: December 8, 2011
    Publication date: June 7, 2012
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Anna-Maria A. HAYS, Troy E. WILSON
  • Modified human growth hormone
    Patent number: 8143216
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: March 27, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria A. Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human interferon polypeptides and their uses
    Patent number: 8119603
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: February 21, 2012
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria Hays, Troy E. Wilson
  • Modified human interferon polypeptides with at least one non-naturally encoded amino acid and their uses
    Patent number: 8097702
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: January 17, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria A. Hays, Troy E. Wilson
  • Pegylated human interferon polypeptides
    Patent number: 8093356
    Abstract: Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: January 10, 2012
    Assignee: Ambrx, Inc.
    Inventors: Anna-Maria A. Hays, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Modified Human Growth Hormone
    Publication number: 20110294161
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: December 1, 2011
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Modified human growth horomone polypeptides and their uses
    Patent number: 7939496
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: May 10, 2011
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Endothelial stem cells, populations, methods of isolation and use thereof
    Patent number: 7833697
    Abstract: The present invention provides stem cells characterized as having the ability to renew and the ability to give rise to endothelial and/or endothelial-like cells, methods of isolating such stem cells and methods of use thereof. Also provided are progeny cells derived from the stem cells of the invention.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: November 16, 2010
    Assignee: Immunex Corporation
    Inventors: William C. Fanslow, III, Anne-Marie C. Rousseau, Thomas O. Daniel
  • Human Interferon Molecules and Their Uses
    Publication number: 20100135959
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: June 2, 2006
    Publication date: June 3, 2010
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. Hays Putnam, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow