Patents by Inventor Thomas P. Leary

Thomas P. Leary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
    Patent number: 6586568
    Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 2003
    Assignee: Abbott Laboratories
    Inventors: John N. Simons, Tami J. Pilot-Matias, George J. Dawson, George G. Schlauder, Suresh M. Desai, Thomas P. Leary, Anthony Scott Muerhoff, James Carl Erker, Sheri L. Buijk, Isa K. Mushahwar
  • Methods for the simultaneous detection of HCV antigens and HCV antibodies
    Publication number: 20030108858
    Abstract: The subject invention relates to methods for the simultaneous detection of Hepatitis C Virus (HCV) antigens as well as antibodies produced in response to HCV antigens. Furthermore, the subject invention allows one to detect antigens in the early, acute stage of infection, even prior to the development of antibodies, thereby allowing for early detection of infected blood and blood products, thus improving the safety of the blood supply.
    Type: Application
    Filed: June 26, 2001
    Publication date: June 12, 2003
    Inventors: Dinesh O. Shah, George A. Dawson, A. Scott Muerhoff, Lily Jiang, Robin A. Gutierrez, Thomas P. Leary, Suresh Desai, James L. Stewart
  • Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
    Patent number: 6558898
    Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 6, 2003
    Assignee: Abbott Laboratories
    Inventors: John N. Simons, Tami J. Pilot-Matias, George J. Dawson, George G. Schlauder, Suresh M. Desai, Thomas P. Leary, Anthony Scott Muerhoff, James Carl Erker, Sheri L. Buijk, Isa K. Mushahwar
  • Method of performing subtractive hybridization using RDA
    Patent number: 6455255
    Abstract: The subject invention relates to improvements in nucleic acid isolation, and more particularly, relates to modifications to the subtractive hybridization method and to reagents such as oligonucleotides that are useful when performing the method.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: September 24, 2002
    Assignee: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Thomas P. Leary, A. Scott Muerhoff, Suresh M. Desai, Isa K. Mushahwar
  • Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
    Patent number: 6451578
    Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 17, 2002
    Assignee: Abbott Laboratories
    Inventors: John N. Simons, Tami J. Pilot-Matias, George J. Dawson, George G. Schlauder, Suresh M. Desai, Thomas P. Leary, Anthony Scott Muerhoff, James Carl Erker, Sheri L. Buijk, Isa K. Mushahwar
  • NON-A,NON-B,NON-C,NON-C,NON-D,NON-E HEPATITIS REAGENTS AND METHODS FOR THEIR USE
    Publication number: 20020119447
    Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Application
    Filed: June 5, 1995
    Publication date: August 29, 2002
    Inventors: JOHN N. SIMONS, TAMI J. PILOT-MATIAS, GEORGE J. DAWSON, GEORGE G. SCHLAUDER, SURESH M. DESAI, THOMAS P. LEARY, ANTHONY SCOTT MUERHOFF, JAMES CARL ERKER, SHERI L. BUIJK, ISA K. MUSHAHWAR
  • Methods of utilizing the TT virus
    Patent number: 6395472
    Abstract: The present invention relates to nucleic oligomer primers or probes useful for detection of TTV in test samples. Also provided are assays which utilize these primers and probes, as well as test kits which contain these oligomer primers and/or probes. In addition, the present invention encompasses the use of TTV nucleotide sequences as nucleic acid vectors and as markers for determining transmission between individuals as well as the route thereof. Additionally, the present invention encompasses a method of detecting TTV infection prior to xenotransplatation of a tissue or organ.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: May 28, 2002
    Assignee: Abbott Laboratories
    Inventors: Thomas P. Leary, James Erker, Michelle Chalmers, John Simons, Larry Birkenmeyer, Scott Muerhoff, Tami Pilot-Matias, Suresh Desai, Isa Mushahwar
  • Methods of utilizing the TT virus
    Publication number: 20010041331
    Abstract: The present invention relates to nucleic oligomer primers or probes useful for detection of TTV in test samples. Also provided are assays which utilize these primers and probes, as well as test kits which contain these oligomer primers and/or. In addition, the present invention encompasses the use of TTV nucleotide sequences as nucleic acid vectors and as markers for determining transmission between individuals as well as the route thereof. Additionally, the present invention invention encompasses a method of detecting TTV infection prior to xenotransplantation of a tissue or organ.
    Type: Application
    Filed: March 23, 2001
    Publication date: November 15, 2001
    Inventors: Thomas P. Leary, James C. Erker, Michelle L. Chalmers, John N. Simons, Larry G. Birkenmeyer, A. Scott Muerhoff, Tami J. Pilot-Matias, Suresh M. Desai, Isa K. Mushahwar
  • Hepatitis GB virus recombinant proteins and uses thereof
    Patent number: 6156495
    Abstract: Recombinantly produced hepatitis GB Virus (HGBV) amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV amino acid sequences and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV recombinantly produced amino acid sequences.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: December 5, 2000
    Assignee: Abbott Laboratories
    Inventors: Tami J. Pilot-Matias, Thomas P. Leary, John N. Simons, Robert J. Carrick, Teresa K. Surowy, Suresh M. Desai, George J. Dawson, Anthony Scott Muerhoff, Isa K. Mushahwar
  • Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
    Patent number: 6051374
    Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 18, 2000
    Assignee: Abbott Laboratories
    Inventors: John N. Simons, Tami J. Pilot-Matias, George J. Dawson, George G. Schlauder, Suresh M. Desai, Thomas P. Leary, Anthony Scott Muerhoff, James Carl Erker, Sheri L. Buijk, Isa K. Mushahwar
  • Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
    Patent number: 5981172
    Abstract: Hepatitus GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and theraeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: November 9, 1999
    Assignee: Abbott Laboratories
    Inventors: John N. Simons, Tami J. Pilot-Matias, George J. Dawson, George G. Schlauder, Suresh M. Desai, Thomas P. Leary, Anthony Scott Muerhoff, Sheri L. Buijk, James Carl Erker, Isa K. Mushahwar
  • Detection of hepatitis GB virus genotypes
    Patent number: 5807670
    Abstract: HGBV-C oligonucleotides from the 5' end of HGBV-C useful for the detection and genotyping of HGBV-C isolates. Also provided are assays which utilize these oligonucleotides.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: September 15, 1998
    Assignee: Abbott Laboratories
    Inventors: Anthony Scott Muerhoff, John N. Simons, Thomas P. Leary, Larry Birkenmeyer, James C. Erker, Michelle Chalmers, George J. Dawson, Suresh M. Desai, Isa K. Mushahwar
  • Nucleic acid detection of hepatitis GB virus
    Patent number: 5709997
    Abstract: Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: January 20, 1998
    Assignee: Abbott Laboratories
    Inventors: Ronald L. Marshall, Cynthia Jou, John N. Simons, Thomas P. Leary, A. Scott Muerhoff, Suresh M. Desai, Isa K. Mushahwar