Abstract: The invention relates to methods of treating or preventing obesity, type 2 diabetes, metabolic syndrome, or glucose intolerance using pyrido[3,2-e]pyrazines which are inhibitors of PDE10. The invention further relates to methods of reducing body fat or body weight.

Abstract: A quilting table (20) includes a frame (22) having box channel rails (50, 52), a first carriage (212), moveable relative to a longitudinal dimension (30) of the frame (22), having wheels (224) engaged with the box channel rails (50, 52), and a second carriage (214), moveable relative to a transverse dimension (32) of the frame (22), supporting a sewing machine (34). A fabric support system (24) includes three fabric payout bars (128, 130, 132) and a take-up bar (134). Compressive force is utilized between the bars (128, 130, 132, 134) and their supports (120, 122) for fabric tensioning. The bars have a rectangular cross-sectional shape and indicia (190) for facilitating fabric placement. An overhead shelf (28) extends across dimension (30) of the frame (22) so that an operator on a needle side (51) of the quilting table (20) can currently view a quilting guide (268) and the fabric (206).

Abstract: The invention relates to pyrido[3,2-e]pyrazines, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10, as active compounds for treating diseases of mammals including a human which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 10 activity in the central nervous system. More particularly, the invention relates to the treatment of neurologic and psychiatric disorders, for example psychosis and disorders comprising cognitive deficits as symptoms.

Abstract: A pump assembly for a chilled beverage dispenser includes an axle oriented in a substantially vertical orientation at a predetermined location along a bottom wall surface of the dispenser bowl; an impeller which rotates about an axis defined by the axle; an inner pump shell that fits over the axle and defines an internal cavity for enclosing the impeller without impeding rotation of the impeller; and an outer pump shell that fits over and engages the lower pump shell, with a cavity being defined and maintained between the inner pump shell and the outer pump shell. As the bladed impeller rotates, beverage is drawn into the pump assembly along the bottom wall surface of the dispenser bowl, and is also discharged along the bottom wall surface of the dispenser bowl, thus providing maximum agitation of the beverage.

Abstract: A tubular support structure (20) includes a first section (22) and a second section (24) longitudinally interconnected with the first section (22). A third section (66) is longitudinally interconnected with the second section (24), and has an end that abuts an end of the first section (22) to form a butt joint (76). A fastener system (46) couples the first and third sections (22, 66) with the second section (24), the fastener system (46) being retained internal to the first, second, and third sections (22, 24, 66). Multiple sections can be assembled to form a variable length support (20), with the resulting multiple butt joints (76) formed between pairs of sections along support (20) being longitudinally offset along support (20) relative to one another.

Abstract: A stitch regulator (50) for use with a sewing machine (34) transported by a moveable platform (26) includes a housing (52) configured to be coupled to one of the sewing machine (34) and the moveable platform (26). An X-axis rate sensor (92) and a Y-axis rate sensor (96) determine movement of the sewing machine (34) on the moveable platform (26). A microcontroller (118) is contained in the housing (52) and is in communication with the sensors (92, 96). The microcontroller (118) generates a motor control signal (126) in response to the movement of the sewing machine (34) for input into a motor control input port (88) of the sewing machine (34).

Abstract: A chilled beverage dispenser has a “holeless” bowl and uses a cradle evaporator to achieve cooling of the beverage. In one exemplary embodiment, the cradle evaporator comprises three panels—a bottom panel and two side panels, the side panels being bolted or similarly fastened to the edges of the bottom panel in a substantially perpendicular orientation relative to the bottom panel. The bottom and side panels each define a continuous and sinuous channel, which carries a cooling medium. The dispenser bowl preferably is constructed of a thin-walled plastic, such that when the dispenser bowl is received in the cradle evaporator, heat transfer is achieved through the bottom wall and portions of the side walls of the bowl.

Abstract: A cable isolator is provided for automatically performing cable breaks for testing of host bus adapters. A workstation includes a host bus adapter, such as a Fibre Channel storage controller, to be tested. The host bus adapter is connected to one or more storage modules through the cable isolator. The cable isolator includes two transceivers, one of which is connected to the host bus adapter and the other being connected to the storage modules. The two transceivers are also connected to each other internally. The cable isolator also includes a programmable logic device or controller that is used to enable and disable the two transceivers at set intervals. The one or more output disable signals are then provided to the transceivers to perform the cable break. The cable isolator may be an expansion card installed within the workstation. Thus, the workstation may communicate with the cable isolator through an expansion bus.

Abstract: An apparatus and method for brewing coffee or a similar brewed beverage allows a consumer to select a desired strength, and then, a serving of the brewed beverage is promptly brewed and dispensed in response to that selection. Regardless of the selected strength, a constant volume of beverage results; in other words, the strength of the brewed beverage is not altered by merely adding or subtracting water.

Abstract: A cable isolator is provided for automatically performing cable breaks for testing of host bus adapters. A workstation includes a host bus adapter, such as a Fibre Channel storage controller, to be tested. The host bus adapter is connected to one or more storage modules through the cable isolator. The cable isolator includes two transceivers, one of which is connected to the host bus adapter and the other being connected to the storage modules. The two transceivers are also connected to each other internally. The cable isolator also includes a programmable logic device or controller that is used to enable and disable the two transceivers at set intervals. When the cable connection is to be broken, the programmable logic device generates one or more output disable signals. The one or more output disable signals are then provided to the transceivers to perform the cable break. An on-time and an off-time may be set using switches or dials.

Abstract: A quilting table (20) includes a frame (22) having box channel rails (50, 52), a first carriage (212), moveable relative to a longitudinal dimension (30) of the frame (22), having wheels (224) engaged with the box channel rails (50, 52), and a second carriage (214), moveable relative to a transverse dimension (32) of the frame (22), supporting a sewing machine (34). A fabric support system (24) includes three fabric payout bars (128, 130, 132) and a take-up bar (134). Compressive force is utilized between the bars (128, 130, 132, 134) and their supports (120, 122) for fabric tensioning. The bars have a rectangular cross-sectional shape and indicia (190) for facilitating fabric placement. An overhead shelf (28) extends across dimension (30) of the frame (22) so that an operator on a needle side (51) of the quilting table (20) can currently view a quilting guide (268) and the fabric (206).

Abstract: An apparatus and method for brewing coffee or a similar brewed beverage allows a consumer to select a desired strength, and then, a serving of the brewed beverage is promptly brewed and dispensed in response to that selection. Regardless of the selected strength, a constant volume of beverage results; in other words, the strength of the brewed beverage is not altered by merely adding or subtracting water.

Abstract: A quilting table (20) includes a frame (22) having box channel rails (50, 52), a first carriage (212), moveable relative to a longitudinal dimension (30) of the frame (22), having wheels (224) engaged with the box channel rails (50, 52), and a second carriage (214), moveable relative to a transverse dimension (32) of the frame (22), supporting a sewing machine (34). A fabric support system (24) includes three fabric payout bars (128, 130, 132) and a take-up bar (134). Compressive force is utilized between the bars (128, 130, 132, 134) and their supports (120, 122) for fabric tensioning. The bars have a rectangular cross-sectional shape and indicia (190) for facilitating fabric placement. An overhead shelf (28) extends across dimension (30) of the frame (22) so that an operator on a needle side (51) of the quilting table (20) can currently view a quilting guide (268) and the fabric (206).

Abstract: The invention relates to substituted 5-hydroxyindoles with N-oxide groups, processes for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.

Abstract: A quilting table (20) includes a frame (22) having box channel rails (50, 52), a first carriage (212), moveable relative to a longitudinal dimension (30) of the frame (22), having wheels (224) engaged with the box channel rails (50, 52), and a second carriage (214), moveable relative to a transverse dimension (32) of the frame (22), supporting a sewing machine (34). A fabric support system (24) includes three fabric payout bars (128, 130, 132) and a take-up bar (134). Compressive force is utilized between the bars (128, 130, 132, 134) and their supports (120, 122) for fabric tensioning. The bars have a rectangular cross-sectional shape and indicia (190) for facilitating fabric placement. An overhead shelf (28) extends across dimension (30) of the frame (22) so that an operator on a needle side (51) of the quilting table (20) can currently view a quilting guide (268) and the fabric (206).

Abstract: A cable isolator is provided for automatically performing cable breaks for testing of host bus adapters. A workstation includes a host bus adapter, such as a Fibre Channel storage controller, to be tested. The host bus adapter is connected to one or more storage modules through the cable isolator. The cable isolator includes two transceivers, one of which is connected to the host bus adapter and the other being connected to the storage modules. The two transceivers are also connected to each other internally. The cable isolator also includes a programmable logic device or controller that is used to enable and disable the two transceivers at set intervals. When the cable connection is to be broken, the programmable logic device generates one or more output disable signals. The one or more output disable signals are then provided to the transceivers to perform the cable break. An on-time and an off-time may be set using switches or dials.

Abstract: A cable isolator is provided for automatically performing cable breaks for testing of host bus adapters. A workstation includes a host bus adapter, such as a Fibre Channel storage controller, to be tested. The host bus adapter is connected to one or more storage modules through the cable isolator. The cable isolator includes two transceivers, one of which is connected to the host bus adapter and the other being connected to the storage modules. The two transceivers are also connected to each other internally. The cable isolator also includes a programmable logic device or controller that is used to enable and disable the two transceivers at set intervals. The one or more output disable signals are then provided to the transceivers to perform the cable break. The cable isolator may be an expansion card installed within the workstation. Thus, the workstation may communicate with the cable isolator through an expansion bus.

Abstract: The invention relates to an apparatus for combining under sterile conditions a liquid component held in a first container and a solid or liquid component held in a second container.

Abstract: An apparatus for combining liquid or solid components stored in containers includes a cylindrical hollow body for receiving end closures of the containers and at least one cannula for penetrating the end closures. The cannula is mounted in a cannula holder movable in the hollow body, and retainer bridges connect the cannula holder to an inner wall surface of the hollow body. The retainer bridges fracture after the cannula penetrates the end closure in the first container so that the cannula moves toward the second container to penetrate the closure in the second container.Also disclosed is a system including the apparatus, two containers, and outer packaging enclosing the containers and the hollow body.