Abstract: An angiographic examination method for the representation of flow properties of vessels of an object under examination is presented. To determine blood-flow parameters in 3-D with high temporal resolution, at least one 4-D DSA sequence is acquired for the generation of measurement-based 4-D DSA data sets. A model-based method determines time-dependent volume data sets, which, in terms of time, lie between the time-dependent volume data sets of the measurement-based 4-D DSA method.

Abstract: A method for positioning a stent able to be deployed to support a vessel in a blood vessel, especially in the cardiology, with the stent after its provisional placement in a not yet deployed state in an area intended for the support of the vessel, being at least partly automatically deployed as a function of at least one triggering signal for final positioning in the blood vessel.

Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.

Abstract: 2-D projection images show the variation over time of the distribution of a contrast medium in an examination subject. Each projection image comprises pixels having pixel values corresponding to one another in the projection images that are determined by identical areas of the examination subject. A computer subdivides an image that is to be displayed from the projection images into parcels in one perfusion region. For each parcel, the computer determines a characteristic value and, based on the characteristic value, a projection color. It assigns the projection color to the parcel. The characteristic value is determined based on the pixel values occurring in the parcel of the projection image or their differences from the pixel values of a corresponding parcel of another projection image. The computer outputs a subarea of the projection image containing the perfusion region. It represents each parcel of the perfusion region in its assigned projection color.

Abstract: A system and method for obtaining perfusion images is disclosed. The system and method includes hardware and software for determining physiological characteristics of a patient and determining imaging parameter values for an imaging modality based on the patient's physiological characteristics. The system also includes a controller operative to receive the imaging parameter values for controlling an X-ray device. The X-ray device is coupled with the controller and acquires projection images of the patient, and outputs the projection images to a perfusion evaluation computer for evaluating the perfusion of an region of interest represented in the projection images. The perfusion rate of the region of interest is then output to an output device, such as a display or printer.

Abstract: In a method and apparatus for optically-based acquisition of slice images from a vessel of a subject, and for combining the slice images to provide an intuitively recognizable visualization of a pathology in the vessel, slice images of the vessel are acquired during pullback of an optical probe of the optically-based slice imaging system, while simultaneously acquiring an ECG signal from the subject. The slice images and the ECG signal are registered, and slice images acquired at a selected cardiac phase are combined into a scene. The slice images in the scene are subjected to a first data transformation to shift the vessel midpoint in each slice image to the image center of each slice image. After the first data transformation, the slice images in the scene are subjected to a second data transformation to produce the visualization. The second transformation, for example, can be a curved planar reformation to allow the vessel to be shown in longitudinal section.

Abstract: A system and method provide an optimized workflow and a dedicated user interface for image visualizations that facilitate medical diagnosis. Image data may be acquired via an imaging procedure at a remote medical facility. A physician may review the images on a display and mark-up/modify the images via the interface to create user-defined data. The image and user-defined data may be transmitted to a service provider. At the service provider, a software technician may generate a medical simulation using the image and user-defined data. The medical simulation may simulate actual conditions within the patient. Subsequently, the simulation results may be transferred to, or otherwise remotely accessed via a network from, the remote medical facility. As a result, medical treatment provided by remote facilities, which may only have limited resources in terms of personnel and equipment, may be enhanced and inefficiencies associated with the generation of medical simulations may be alleviated.

Abstract: A method of guiding a catheter during a treatment procedure includes acquiring scan data of a patient volume in position for the treatment procedure, registering volume data of the patient volume to the scan data, acquiring fluoroscopic data for the patient volume during the treatment procedure, and generating a volume representation of the fluoroscopic data during the treatment procedure. Generating the volume representation includes superimposing the fluoroscopic data on the volume data based on the registering. The volume representation of the fluoroscopic data is displayed, the volume representation showing a position of a mitral valve clip carried by the catheter relative to the patient volume.

Abstract: A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets.

Abstract: The invention relates to an arrangement for assisting a percutaneous intervention, comprising an imaging system for tomographic imaging, a robot registered therewith and devices for capturing movements of the patient. A processing unit registers a 4D image dataset recorded before the intervention with a 2D or 3D image dataset of the patient which was recorded immediately before the intervention by the imaging system at a defined respiratory position. From this image data, the access path is transmitted to the robot as a function of the movements captured during recording the 4D image dataset and registration, said robot in turn, depending on the instantaneous movement data, holding the instrument on a predetermined target path and preventing the instrument from being advanced by the person if and as long as the instantaneous movement data does not match the previously recorded movement data. The arrangement reduces the risk of puncture errors.

Abstract: An X-ray imaging apparatus has at least one X-ray image system rotatable about an examination volume. The X-ray image system is controlled such that during a continuous rotation of the system, at least one 2D projection image is recorded. An image generation facility generates the 2D projection image from the measured data. The X-ray source includes an X-ray focus which can be changed in terms of position, which, during the recording of the 2D projection image, moves counter to the direction of rotation of the X-ray image system such that its spatial position in a fixed coordinate system does not change. The X-ray detector records several 2D partial images, from which the 2D projection image is calculated with the rotational movement of the X-ray detector being at least approximately compensated. The 2D projection images have significantly reduced image blur.

Abstract: A method (100) of aneurysm analysis (110) and virtual stent simulation (120) for endovascular treatment of sidewall intracranial aneurysms.

Abstract: A method for assisting a person performing a minimally invasive intervention with a catheter involving a puncture of a septum, in particular of a heart, is proposed. A three-dimensional image data record is recorded showing an anatomical structure in the region of the septum. An item of septum information showing the position of the septum is determined in the image data record and additional information is derived from the position of the anatomical structure influencing or showing the selection of a puncture site. During the intervention, the fluoroscopic images of the region are continuously recorded and a current fluoroscopic image is displayed and superimposed with the septum information and/or the additional information based on a registration of the image data record with the fluoroscopic images.

Abstract: A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).

Abstract: The invention relates to a method for reconstructing a 3D presentation of a hollow organ based on two-dimensional catheter images, comprising: detecting at least two fluoroscopy images at two different angles of the hollow organ; determining a start position of the catheter from the fluoroscopy images in a three-dimensional model of the hollow organ or a catheter guide; determining a probable withdrawal path of the catheter based on the three-dimensional model; withdrawing the catheter while recording the catheter images and assigning a withdrawal length to each catheter image; determining the deviation of the position of the catheter from a central path running through the middle of the hollow organ and the orientation of the catheter for each catheter image based on the withdrawal path and the withdrawal length; and reconstructing the 3D presentation from the two-dimensional catheter images as well as the deviation of the position of the catheter.

Abstract: Method for creating image recordings of blood vessel system of a patient, comprising: after administering contrast agent an image recording is created in a first image recording region of a first position of a detector, the diffusion of the contrast agent is observed to determine a current diffusion position; the position of the detector is changed to a second position as a function of the current diffusion position; an image recording of a second image recording region of the second position of the detector is created; and a part of an image recording in the first position extending in the region between the current diffusion position and the end of the first image recording region and recorded without contrast agent is used as a mask to evaluate a locationally correlated part, recorded with contrast agent, of the image recording in the second position for digital subtraction angiography.

Abstract: A method for predicting aneurysm growth based on CFD simulations derived from at least two angiography recordings is proposed. A first 3-D recording of the aneurysm is recorded at a first time and a first vascular geometry is determined for simulating a first CFD simulation. A second 3-D recording is recorded at a second time and a second vascular geometry is determined for simulating a second CFD simulation. The two 3-D recordings are registered and a local growth rate is determined from the two 3-D recordings. The local growth rate is correlated between the two vascular geometries with hemodynamically derived parameters from the first CFD simulation. A future vascular geometry and/or a future local growth rate is predicted based on the correlation parameters, the hemodynamic parameters from the second CFD simulation and the second vascular geometry.

Abstract: A system and method of treatment of mitral valve insufficiency using an implantable medical device is described. The system uses a C-arm X-ray device configured to produce computed-tomographic (CT)-like images, and to superimpose the CT-like images on a fluoroscopic image taken with the same X-ray device as a part of the treatment procedure. The fluoroscopic images are used to guide a catheter in the patient so as to place the medical device in a proper position. The efficacy of the procedure may be assessed using a non-invasive or minimally invasive acoustic imaging technique.

Abstract: A method for simulating a blood flow in a vascular segment of a patient is proposed. A 3D image dataset of an examination region is recorded by a radiographic diagnostic device for generating a 3D vascular model. Contrast agent propagation in the examination region is captured by a dynamic 2D angiography method for generating a real 2D angiography recording. A CFD simulation of the blood flow is performed in the 3D vascular model based on a blood flow parameter for generating a virtual 2D angiography recording. A degree of correspondence between the real and the virtual 2D angiography recordings is determined from identical angulation and adjusted recording geometry of the patient and compared with predefinable tolerance values. The CFD simulation is iteratively optimized while changing the blood flow parameter as a function of the comparison. The degree of correspondence is outputted when the optimum CFD simulation is achieved.

Abstract: There is described an analysis method for at least one image data record of an examination object, wherein each image data record features a multiplicity of image data elements. A position in a multidimensional space is assigned to each image data element. Each image data element features an image data value. The image data values of positionally corresponding image data elements of the image data records are specified by means of at least essentially positionally identical regions of the examination object. A computer automatically divides the image data records into empty regions and signal regions, applying an overall assignment rule which is based on the image data values of the image data elements of a plurality of image data records, such that each image data element of each image data record is assigned to either its empty region or its signal region.