Abstract: The present disclosure provides compositions and methods based on peptide-detectable agent conjugates that are useful for imaging beta cell mass.

Abstract: This invention is in the field of labeled peptide construction for medical treatment and analysis. The invention relates to synthetic labeled peptide compositions, methods of synthesis, and methods of use for the synthetic labeled peptide compositions for medical treatment, imaging, and research purposes.

Abstract: Described herein is a non-invasive quantitative positron emission tomography (PET) nanoreporter technology that allows personalized therapeutic outcome prediction. In a breast cancer mouse model, it was demonstrated that co-injecting Doxil and a Zirconium-89 nanoreporter (89Zr-NRep) enabled highly precise doxorubicin (DOX) quantification. Imaging 89Zr-NRep via PET revealed remarkable Doxil accumulation heterogeneity independent of tumor size.

Abstract: The holding frame is equipped for holding at least one optical element, the holding frame consisting of an opaque material.

Abstract: A lighting device may include: a laser light source arrangement; at least two pivotable mirrors; and at least one light wavelength conversion element. The lighting device is embodied in such a way that light generated by the laser light source arrangement is directed onto at least one light wavelength conversion element by the pivotable mirrors. The at least two pivotable mirrors are embodied in such a way that light reflected at a first pivotable mirror is directable onto a first surface section of at least one light wavelength conversion element in order to form a first illuminatable region of the at least one light wavelength conversion element, and light reflected at a second pivotable mirror is directable onto a second surface section of the at least one light wavelength conversion element in order to form a second illuminatable region of the at least one light wavelength conversion element. The first and second illuminatable regions partly overlap.

Abstract: A headlight module comprising separate phosphors which can be excited by electromagnetic radiation to emit light, and at least one radiation source for exciting the phosphors. Each phosphor is associated with an optical device, so that light emitted by the optical devices is merged into an overall image. Beam splitter devices and beam directing devices are disposed such that electromagnetic radiation emitted by the at least one radiation source is directed on the phosphors. A control device is provided for controlling operation of the at least one radiation source and the beam directing devices.

Abstract: A motor vehicle headlight element is specified which has at least one light-emitting diode and at least one control apparatus. The control apparatus is suitable for processing a signal which is dependent on a measurement variable and for applying a current, corresponding to the signal, to the light-emitting diode. The control apparatus and the light-emitting diode are arranged on a common mount.

Abstract: A cargo restraint system is provided. The system includes a fixed-hook assembly including a frame and a hook extending from the frame. The system also includes a fabric strap including a first end and a second end and a tensioner assembly configured to receive and maintain the second end of the fabric strap therein when in a locked configuration, wherein the tensioner assembly is configured to reduce in length when placed in the locked configuration. At least a portion of the fabric strap is received within the fixed-hook assembly.

Abstract: The present disclosure provides compositions and methods based on peptide-detectable agent conjugates that are useful for imaging beta cell mass.

Abstract: A vehicle lighting device having at least two semiconductor light-emitting elements may include at least a first light-emitting element group and a second light-emitting element group, each having at least one semiconductor light-emitting element, the light-emitting element groups being selectively drivable and the first light-emitting element group having at least a foglight function, the first light-emitting element group and the second light-emitting element group having a daytime running light function.

Abstract: A lighting apparatus may include an electrically conductive housing, in whose interior at least one light source and at least one electromagnetic radiation-emitting circuit component configured to operate the at least one light source are arranged; and an electrically conductive cover configured to cover the at least one circuit component; wherein the cover and the housing are electrically connected to one another.

Abstract: This document relates to compounds useful for targeting PARP1. Also provided herein are methods for using such compounds to detect and image cancer cells.

Abstract: A cargo restraint system is provided. The system includes a fixed-hook assembly including a frame and a hook extending from the frame. The system also includes a fabric strap including a first end and a second end and a tensioner assembly configured to receive and maintain the second end of the fabric strap therein when in a locked configuration, wherein the tensioner assembly is configured to reduce in length when placed in the locked configuration. At least a portion of the fabric strap is received within the fixed-hook assembly.

Abstract: A retaining frame (2) having at least one optical element (3) secured thereto by injection molding, with the at least one optical element (3) being embodied for beam shaping at least by means of total internal reflection and/or diffraction.

Abstract: A cargo restraint system is provided. The system includes a fixed-hook assembly including a frame and a hook extending from the frame. The system also includes a fabric strap including a first end and a second end and a tensioner assembly configured to receive and maintain the second end of the fabric strap therein when in a locked configuration, wherein the tensioner assembly is configured to reduce in length when placed in the locked configuration. At least a portion of the fabric strap is received within the fixed-hook assembly.

Abstract: A headlight module comprising at least one phosphor which can be excited to emit light by means of electromagnetic radiation; at least one radiation source for exciting the at least one phosphor; at least one carrier device for the at least one phosphor; and at least one beam directing device which is disposed such that it directs electromagnetic radiation emitted by the at least one radiation source onto the at least one phosphor.

Abstract: A motor vehicle headlight element is specified which has at least one light-emitting diode and at least one control apparatus. The control apparatus is suitable for processing a signal which is dependent on a measurement variable and for applying a current, corresponding to the signal, to the light-emitting diode. The control apparatus and the light-emitting diode are arranged on a common mount.

Abstract: A motor vehicle headlight element is specified which has at least one light-emitting diode and at least one control apparatus. The control apparatus is suitable for processing a signal which is dependent on a measurement variable and for applying a current corresponding to the signal, to the light-emitting diode. The control apparatus and the light-emitting diode are arranged on a common mount.

Abstract: A solid-state light source (10) comprising a plurality of LED units (12) arrayed to emit light generally about an axis (14). Each of the LED units (12) can comprise a number of LEDs, for example, up to five. They may all emit in a single color or multiple colors can be combined for a specific effect. A light transmissive light guide (16) is associated with the LED units (12) and has a plurality of input widows (18). Each LED unit (12) faces a respective input window (18) and each window (18) transversely intercepts the axis (14) and receives light from the LED units (12). The input windows (18) lead to a common output window (20) that is axially aligned with the input windows (18). The light guide (16) has smooth sidewalls (22) that extend between the input windows (18) and the output window (20).

Abstract: A motor vehicle headlight module having at least two lighting units (1) is specified. Here, each lighting unit (1) comprises at least one light-emitting diode chip (2). Different lighting units (1) are provided here for different lighting functions. Furthermore, the motor vehicle headlight module has a common heat sink (6) for the lighting units, to which heat sink the lighting units are thermally connected, and a common current-stabilizing electronic system (8) for supplying voltage to the lighting units.