Patents by Inventor Thomas Rudel

Thomas Rudel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALMONELLA VACCINE FOR THE TREATMENT OF CORONAVIRUS
    Publication number: 20220047697
    Abstract: The present invention provides live-attenuated bacterium of the genus Salmonella comprising a recombinant plasmid encoding a fusion protein, wherein the fusion protein comprises a coronavirus antigen and an adjuvant peptide.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 17, 2022
    Inventors: Thomas Rudel, Birgit Bergmann
  • Benzodiazepine derivatives for use in the treatment of Chlamydiales infections
    Patent number: 11136299
    Abstract: The invention relates to a method for treating a Chlamidyales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein R1, R2, R3 and Ar are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: October 5, 2021
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Hajer Abdelkafi, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Adamantane or pinene derivatives for use in the treatment of chlamydiales infections
    Patent number: 10039727
    Abstract: The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: W-L1-NH-L2-Ar?? (I) Wherein W, L1, L2 and Ar are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: August 7, 2018
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Valérie Pons, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Quinazolinone derivatives for use in the treatment of chlamydiales infections
    Patent number: 9598406
    Abstract: The present invention relates to a method for treating a Chlamydiae infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein, R1, R2, R3, R4 and p are as defined in claim 1.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: March 21, 2017
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Karen Hinsinger, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160310448
    Abstract: The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: W—L1—NH—L2—Ar??(I) Wherein W, L1, L2 and Ar are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Valérie Pons, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Benzodiazepine Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160311783
    Abstract: The invention relates to a method for treating a Chlamidyales infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein R1, R2, R3 and Ar are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Hajer Abdelkafi, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • Quinazolinone Derivatives for Use in the Treatment of Chlamydiales Infections
    Publication number: 20160311815
    Abstract: The present invention relates to a method for treating a Chlamydiae infection comprising the administration of a therapeutically effective amount of a compound of formula (I) to a subject in need thereof: Wherein, R1, R2, R3, R4 and p are as defined in claim 1.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 27, 2016
    Inventors: Daniel Gillet, Julien Barbier, Jean-Christophe Cintrat, Karen Hinsinger, Thomas Rudel, Jo-Ana Herweg, Annette Fischer
  • L-amino acid oxidase with cytotoxic activity from
    Patent number: 8784813
    Abstract: The present invention relates to a cytotoxic polypeptide which is an L-amino acid oxidase isolated from the ink of the sea hare Aplysia punctata.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: July 22, 2014
    Inventors: Daniel Butzke, Sigrid Goedert, Michael Dittrich, Thomas Rudel, Thomas Meyer
  • Prohibitin as target for cancer therapy
    Patent number: 8658615
    Abstract: The present invention relates to pharmaceutical compositions comprising inhibitors of Prohibitin (PHB) for the prevention or/and treatment of hyperproliferative disorders.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: February 25, 2014
    Assignee: AEterna Zentaris GmbH
    Inventors: Krishnaraj Rajalingam, Thomas Rudel
  • PROHIBITIN AS TARGET FOR CANCER THERAPY
    Publication number: 20120121575
    Abstract: The present invention relates to pharmaceutical compositions comprising inhibitors of Prohibitin (PHB) for the prevention or/and treatment of hyperproliferative disorders.
    Type: Application
    Filed: October 18, 2011
    Publication date: May 17, 2012
    Applicant: Dr. Thomas RUDEL
    Inventors: Krishnaraj RAJALINGAM, Thomas RUDEL
  • Nucleic acid molecules encoding proteins which impart the adhesion of cells to human cells
    Patent number: 8114971
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: February 14, 2012
    Assignee: Max-Planck Gesellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Thomas F. Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • INFLUENZA TARGETS
    Publication number: 20110150897
    Abstract: The present invention relates to pharmaceutical compositions comprising modulators of kinases, kinase binding polypeptides or/and an inhibitor for influenza virus replication for the prevention or/and treatment of influenza.
    Type: Application
    Filed: October 11, 2007
    Publication date: June 23, 2011
    Inventors: Thomas F. Meyer, Alexander Karlas, Nikolaus Machuy, Jan David Manntz, Elke Muller, Thomas Rudel
  • L-AMINO ACID OXIDASE WITH CYTOTOXIC ACTIVITY FROM APLYSIA FUNCTATA
    Publication number: 20090028864
    Abstract: The present invention relates to a cytotoxic polypeptide which is an L-amino acid oxidase isolated from the ink of the sea hare Aplysia punctata.
    Type: Application
    Filed: June 27, 2008
    Publication date: January 29, 2009
    Inventors: Daniel BUTZKE, Sigrid Goedert, Michael Dittrich, Thomas Rudel, Thomas Meyer
  • Prohibitin as Target for Cancer Therapy
    Publication number: 20080241144
    Abstract: The present invention relates to pharmaceutical compositions comprising inhibitors of Prohibitin (PHB) for the prevention or/and treatment of hyperproliferative disorders.
    Type: Application
    Filed: September 23, 2005
    Publication date: October 2, 2008
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften, e. V.
    Inventors: Krishnaraj Rajalingam, Thomas Rudel
  • Nucleic acid molecules encoding proteins which impart the adhesion of Neisseria cells to human cells
    Publication number: 20080200665
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Application
    Filed: May 3, 2007
    Publication date: August 21, 2008
    Inventors: Thomas F. Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • L-amino acid oxidase with cytotoxic activity from
    Patent number: 7407784
    Abstract: The present invention relates to a cytotoxic polypeptide which is an L-amino acid oxidase isolated from the ink of the sea hare Aplysia punctata.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: August 5, 2008
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
    Inventors: Daniel Butzke, Sigrid Goedert, Michael Dittrich, Thomas Rudel, Thomas Meyer
  • Identification of a new cytotoxic activity from the ink of
    Patent number: 7074889
    Abstract: The present invention relates to novel proteins having cytotoxic activity derived from the sea hare Aplysia.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: July 11, 2006
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften. E.V.
    Inventors: Daniel Butzke, Nikolaus Machuy, Thomas Rudel, Thomas F. Meyer
  • Nucleic acid molecules encoding proteins which impart the adhesion of Neisseria cells to human cells
    Publication number: 20050124037
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Application
    Filed: July 14, 2003
    Publication date: June 9, 2005
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN e.V.
    Inventors: Thomas Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • Methods for dna mutagenesis and dna cloning
    Publication number: 20040248131
    Abstract: The invention relates to methods and reagent kits for DNA manipulation, in particular for site-specific mutagenesis or for cloning.
    Type: Application
    Filed: April 2, 2004
    Publication date: December 9, 2004
    Inventors: Thomas Rudel, Nikolaus Machuy
  • Identification of a new cytotoxic activity from the ink of aplysia punctata
    Publication number: 20040101940
    Abstract: The present invention relates to novel proteins having cytotoxic activity derived from the sea hare Aplysia.
    Type: Application
    Filed: September 23, 2003
    Publication date: May 27, 2004
    Inventors: Daniel Butzke, Nikolaus Machuy, Thomas Rudel, Thomas F Meyer