Abstract: An account management system for charging for services provided in a telecommunications network, which has at least one first account class and a second account class for a service receiver (consumer), where the accounts in the first account class can be filled upon payment of a fixable rate of value added tax, and the accounts in the second account class can be filled without payment of a rate of value added tax. The inventive method for charging for services provided in a telecommunications network is carried out using an account management system having at least one first account class and a second account class for the service receiver (consumer), where a rate of value added tax is not paid when charging via an account in the first account class, and a fixable rate of value added tax is paid when charging via an account in the second account class.

Abstract: The invention relates to a method of establishing a telecommunications connection between a first subscriber (SA) and a second subscriber (SB) of a telecommunications network (TN), wherein at least the first subscriber (SA) has an Internet terminal (ITA), wherein the first subscriber (SA) sends an information from his Internet terminal (ITA) to a first service unit (WS) for carrying out services for Internet users with a request to the connected to the second subscriber (SB), the first service unit (WS) sends a message to a second service unit (SCP) for carrying out services in a telecommunications network (TN) which contains the call numbers of the above-mentioned subscribers (SA, SB) and the command to establish a (telecommunications) connection between the above-mentioned subscribers (SA, SB) and the second service unit (SCP) establishes a connection between the two above-mentioned subscribers (SA, SB) in the telecommunications network (TN),and further relates to a service unit (WS) for carrying out servic

Abstract: The present invention relates to novel process for the preparation of glycoproteins by mammalian cell culture wherein the sialic acid content of the glycoprotein produced is controlled over a broad range of values by manipulating the cell culture environment. The invention provides for processes in which the sialic acid content of the glycoprotein is modified by changes in cell culture parameters which affect cell specific productivity. Preferred embodiments of the invention include cell culture processes in the osmolality of the cell culture is controlled as well as the concentration of a transcription enhancer during the production phase of the cell culture. The invention further provides for novel preparations of soluble type 1 tumor necrosis factor immunoglobulin G1 and their uses in the treatment of inflammatory or immune related disorders.

Abstract: The present invention relates to novel process for the preparation of glycoproteins by mammalian cell culture wherein the sialic acid content of the glycoprotein produced is controlled over a broad range of values by manipulating the cell culture environment. The invention provides for processes in which the sialic acid content of the glycoprotein is modified by changes in cell culture parameters which affect cell specific productivity. Preferred embodiments of the invention include cell culture processes in the osmolality of the cell culture is controlled as well as the concentration of a transcription enhancer during the production phase of the cell culture. The invention further provides for novel preparations of soluble type 1 tumor necrosis factor immunoglobulin G1 and their uses in the treatment of inflammatory or immune related disorders.