Patents by Inventor Thomas Seewoester

Thomas Seewoester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL CULTURE IMPROVEMENTS
    Publication number: 20190225934
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: August 30, 2018
    Publication date: July 25, 2019
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
  • Modified serum-free cell culture medium
    Patent number: 10119118
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: November 6, 2018
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
  • Cell Culture Improvements
    Publication number: 20170130191
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: June 20, 2016
    Publication date: May 11, 2017
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20160186130
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: March 14, 2016
    Publication date: June 30, 2016
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang D. Chang, Thomas Seewoester
  • Methods of producing adalimumab
    Patent number: 9284371
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: March 15, 2016
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang D. Chang, Thomas Seewoester
  • Cell Culture Improvements
    Publication number: 20160039927
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: October 22, 2015
    Publication date: February 11, 2016
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang D. Chang, Thomas Seewoester
  • Fed-batch methods for producing adalimumab
    Patent number: 9234032
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: January 12, 2016
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
  • Fed-batch method of making anti-TNF-alpha antibody
    Patent number: 9090867
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: July 28, 2015
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang D. Chang, Thomas Seewoester
  • Fed batch method of making anti-TNF-alpha antibodies
    Patent number: 9073988
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: July 7, 2015
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20150125905
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 7, 2015
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nicole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • Cell Culture Improvements
    Publication number: 20150093784
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 2, 2015
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang D. Chang, Thomas Seewoester
  • Cell Culture Improvements
    Publication number: 20150087024
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: December 8, 2014
    Publication date: March 26, 2015
    Inventors: ITZCOATL A. PLA, JOSEPH G. MATUCK, JOHN C. FANN, CHRISTOF SCHULZ, NICHOLE A. ROY, DAVID F. BRUTON, JAMES MCLNTIRE, YU-HSIANG D. CHANG, THOMAS SEEWOESTER
  • Fed-batch method of making human anti-TNF-alpha antibody
    Patent number: 8911964
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: December 16, 2014
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • Fed-batch method of making human anti-TNF-alpha antibody
    Patent number: 8906646
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: December 9, 2014
    Assignee: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20140234905
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: March 26, 2014
    Publication date: August 21, 2014
    Applicant: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20140206038
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: March 26, 2014
    Publication date: July 24, 2014
    Applicant: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20140134675
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: AbbVie Inc.
    Inventors: Itzcoatl A. Pla, Thomas Seewoester, Yu-Hsiang David Chang, James McIntire, David F. Bruton, Nichole A. Roy, Christof Schulz, John C. Fann, Joseph C. Matuck
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20140134674
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: ABBVIE INC.
    Inventors: Joseph C. Matuck, Thomas Seewoester, Yu-Hsiang David Chang, James McIntire, Nicole A. Roy, John C. Fann, Christof Schulz, David F. Bruton, Itzcoatl A. Pla
  • Methods of producing anti-TNF-alpha antibodies in mammalian cell culture
    Patent number: 8663945
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: March 4, 2014
    Assignee: AbbVie Inc
    Inventors: Itzcoatl A. Pla, Joseph C. Matuck, John C. Fann, Christof Schulz, Nicole A. Roy, David F. Bruton, James McIntire, David Chang Yu-Hsiang, Thomas Seewoester
  • CELL CULTURE IMPROVEMENTS
    Publication number: 20120077213
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 29, 2012
    Applicant: Abbott Laboratories
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester