Patents by Inventor Thomas Seewoester

Thomas Seewoester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fed-batch cell culture methods using non-animal-based hydrolysates
    Patent number: 8093045
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: January 10, 2012
    Assignee: Abbott Laboratories
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, David Chang Yu-Hsiang, Thomas Seewoester
  • Cell culture improvements
    Publication number: 20080227136
    Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
    Type: Application
    Filed: September 13, 2007
    Publication date: September 18, 2008
    Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-Hsiang David Chang, Thomas Seewoester
  • Method and media for single cell serum-free culture of CHO cells
    Publication number: 20060115901
    Abstract: The present invention relates to methods and media for single cell serum free culture of CHO cells. Generally, the invention relates to a method of culturing CHO cells at a cell density of less than 100 cells/ml in a serum-free cell culture medium. The medium is sufficient to support the growth of a single CHO cell and comprises a basal medium sufficient to support the growth of CHO cells and a supplemental medium, wherein the combined basal medium and supplemental medium comprise an antioxidant, L-glutamine, iron, ethanolamine, and albumin; and insulin, wherein the insulin may be present in either the basal medium or the supplemental medium, or both. Optionally, the medium may contain EGF or IGF.
    Type: Application
    Filed: October 21, 2005
    Publication date: June 1, 2006
    Inventors: Bahram Valamehr, Thomas Seewoester