Abstract: Biocompatible matrices or implants on which one or more specific cell-interactive molecules (“biomolecules”) can be immobilized have been developed. The matrices allow for the independent control of ligand concentration and matrix strength. In one embodiment, the matrix or implant is modified with one or more moieties capable of complexing bioconjugates prepared from one or more biomolecules. Suitable moieties include phenyl boronic acid complexing agents, such as salicylhydroxamic acid, which can complex to one or more biomolecules containing one or more phenyl boronic acid moieties. The biomolecules may be anchored to the matrix via a spacer molecule, which may allow for greater mobility of the biomolecules in aqueous solution. In one embodiment, the matrix is a hydrogel material which has been doubly-derivatized, wherein ligand concentration and matrix strength can be independently controlled.

Abstract: There is provided an apparatus that includes a film that undergoes a chemical reaction when exposed to a species. The chemical reaction causes an alteration of a physical property of the film as an indicator of the species.

Abstract: A universal joint yoke includes a yoke base and two yoke arms, each respectively having a through extending bearing bore, a circular arc groove having a center that is arranged on a bore axis or is off-set from the bore axis toward the yoke base, and at least one securing recess on the outer face. A separate securing element for each yoke arm has an engagement portion with an outer circumference that is adapted to the circular arc groove and engaging the same and at least one securing portion that projects from the securing element in the direction away from the center and that engages the at least one securing recess and that secures the securing element against rotation around the center. A securing device retains the securing elements on the universal joint yoke.

Abstract: A cover for the open top of a soda can or beer can is substantially round and has a pair of parallel sides together with an annular bevel or chamfer to accommodate either a soda can or a beer can. The beer can has a larger diameter at its annular rim than that of the soda can, so that (in use) the cover is reversed. The cover may contain a trademark, logo, company name or message for promotional purposes. An alternate cover is substantially half-round, and a further embodiment is substantially arcuate.

Abstract: A vacuum cleaner for removing dirt and debris from different surfaces and a method of operating a vacuum cleaner. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Abstract: Provided is a high frequency application apparatus comprising a high frequency generator 1, a probe arrangement 3 which is connected to the high frequency generator 1 and which includes at least two electrodes 8, 9, and at least two lines 11 which connect the electrodes 8, 9 to the high frequency generator 1, which is distinguished in that the lines 11 are combined together in a common cable (5). In that respect the term probes is used to denote not only probes which are suitable for introduction into the body such as for example catheters or electrode needles but also those which are to be fitted externally to the body.

Abstract: A connection arrangement between a vacuum cleaner and a suction tool includes a pivot element pivotably connected to the suction tool and a rotation element rotatably coupled to the pivot element. A suction wand, hose, handle or other vacuum port of the vacuum cleaner is removably connected to a connection end of the rotation element. Coupling ends of the pivot and rotation elements are inserted one in the other, and respectively have circumferential grooves that form a circumferential channel therebetween. Plural partial ring segment elements are received in the circumferential channel to form a connection ring that rotatably secures the pivot and rotation elements. The ring segment elements are inserted into or removed from the channel through a selectively coverable opening in the rotation element or the pivot element. A catch cooperates with a detent to hold a vertically pivoted, rotationally centered rest position of the components.

Abstract: A brush roll is rotatably supported by bearings in a housing of a cleaning brush tool. One of the bearings is incorporated in a removable bearing arrangement that can be rotationally fastened and removed as needed on a cylindrical end of the housing. Preferably collar elements protruding cylindrically from the removable bearing arrangement form bayonet-type catch hooks that selectively engage with bayonet-type catch elements protruding radially outwardly from the cylindrical end sleeve of the housing. A detent on the housing engages a securing element on the removable bearing arrangement to secure the engaged bayonet-type fastening arrangement against rotational release thereof.

Abstract: A filter bag arrangement for a vacuum cleaner includes a bag body of filter material, and a stiffening element in the form of a filter mounting plate with an inlet opening of the bag therein. The vacuum cleaner includes a housing defining a chamber into which the bag may be inserted, a lid to cover the chamber, and a filling pipe stub that is insertable into the inlet opening. Plural individual mounting elements are provided at the outer edge of the stiffening element and are inserted into corresponding individual receivers of the housing so as to spatially position and fix the inlet opening of the filter bag arrangement relative to the housing of the vacuum cleaner.

Abstract: A vehicle framing system for framing an automotive vehicle body from a plurality of separate body components wherein the body components each include a reference surface. The system includes an assembly station having spaced-apart frame members positioned so that, when a vehicle carrier supporting the vehicle body components is positioned at the assembly station, the frame members end along opposite sides of the vehicle carrier. At least two docking stations are secured to each frame member at predetermined locations. A robot mounts its associated tool arm with a docking station. At least one set of reference block and framing clamp is secured to each tool arm and these framing clamps maintain the reference surfaces of the vehicle body components against the reference blocks to hold the vehicle components at a predetermined position relative to each other.

Abstract: The application apparatus according to the invention for applying a high frequency current for thermal sclerosis of body tissue, includes an electrode array (7) with at least three active electrodes (1-6) which are electrically conductingly connected to the body tissue, a high frequency generator (17) which can be individually electrically connected to the active electrodes (1-6) for producing a high frequency voltage, and a measuring device (13) for measuring the impedance of the tissue between the active electrodes (1-6). In addition the application apparatus includes a selector device (15) for selecting a sub-array (19) including at least two active electrodes (5, 6) from the electrode array (7), the selection being effected on the basis of the measured impedance.

Abstract: A medical device assembly for cutting body tissue by means of electrotomy, includes a generator for a high frequency alternating current which can be delivered by way of a pole and an opposite pole, wherein each pole is connected to at least one respective output terminal of the generator; a gripping instrument with two gripping arms which each have at least one respective gripping surface and which are connected together in such a way that the gripping surfaces are movable towards each other, wherein the gripping surface is at least partially electrically conductive and each is individually electrically connected to a respective terminal or they are electrically connected to a common terminal for an electrical supply line; and a cutting instrument which has a handle and a cutting electrode, wherein in operation the cutting electrode is connected to a pole of the generator and both gripping surfaces are connected to the opposite pole of the generator.

Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.

Abstract: The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.

Abstract: An electrode arrangement is provided having at least one electrode for insertion into a human or animal body for electrothermal treatment of the body. The electrode is situated on an electrode support and is connected to an alternating current source via a supply lead and to a temperature stabilizer device for influencing the effective temperature profile in a treatment area. The electrode support and the electrode, or electrodes, are constructed for direct insertion into body tissue, said insertion being channel forming. The temperature stabilizer device has a timed heating device.

Abstract: The disclosure provides a probe arrangement having a distal probe tip and a proximal hand portion for the electrothermal coagulation of tissue. The probe arrangement has at least a first and a second electrode in the region of the distal probe tip. An inner conductor of the probe arrangement extends from the distal probe tip to the proximal hand portion and contacts the first electrode in the distal probe tip. An outer conductor of the probe arrangement extends from the distal probe tip to the proximal hand portion and serves to electrically contact the second electrode in the distal probe tip. The inner and outer conductors of the probe arrangement are electrically insulated from each other. Furthermore the inner conductor is selected in such a way that the flexural stiffness of the probe arrangement is increased between the probe tip and the hand portion.

Abstract: An exhaust filter unit is arranged outwardly surrounding at least a major portion of a housing of a vacuum cleaner. The dirt-laden incoming airflow is filtered through a primary filter, then blown by a suction motor unit into an annular exhaust air space between the vacuum cleaner housing and the exhaust filter unit. Thereby, the filtered air is exhausted in a diffused manner through the large surface area of the exhaust filter unit. Preferably, the exhaust filter unit has a cylindrical tubular configuration that completely externally surrounds a cylindrical portion of the vacuum cleaner housing.

Abstract: A brush roller accessory for a vacuum cleaner includes a main support roller and a power-driven brush roller rotatably arranged in a housing, and a spring-biased adjusting roller that adjustably protrudes from the housing to bear some of the total contact force of the accessory against a floor, to reduce or relieve the contact force exerted by the brush roller against the floor. The adjusting roller is rotatably mounted on a pivot lever, having a first end pivotally connected to the housing and a second end connected to a spring that biases the lever to pivot the adjusting roller outwardly from the housing. A rotary knob with several stop surfaces selects an upper limit on the pivot range of the lever and the adjustment height of the adjusting roller. A coupling link pivots the adjusting roller to a maximally protruding position to lift the brush roller into a parking position.

Abstract: A device for electrothermal treatment of the human or animal body, in particular for tissue coagulation or electrotomy, has an elongate applicator with at least two electrodes for insertion into the body to be treated. To produce an electrical or electromagnetic field for heating the body tissue in the treatment region, the two electrodes are arranged on the applicator in electrically mutually insulated and mutually spaced relationship and are each connected by way of a respective feed line to an extracorporally arranged high-frequency generator, in order to be able better to control the treatment process there is provided a signal source which emits a signal that provides the user with information about the condition of the body tissue between the two electrodes during a treatment process.

Abstract: An electrode arrangement is provided having at least one electrode for insertion into a human or animal body for electrothermal treatment of the body. The electrode is situated on an electrode support and is connected to an alternating current source via a supply lead and to a temperature stabilizer device for influencing the effective temperature profile in a treatment area. The electrode support and the electrode, or electrodes, are constructed for direct insertion into body tissue, said insertion being channel forming. The temperature stabilizer device has a timed heating device.