Abstract: An implantable medical lead may include an electrode at a distal portion of the lead that is configured to monitor or provide therapy to a target site. The lead may include a visible indicator that is visible to the naked eye of a clinician at a medial portion of the lead that is configured to indicate when the electrodes of the lead are longitudinally and radially aligned properly to monitor or treat the target site. A clinician may insert the lead into the patient using an introducer sheath inserted to a predetermined depth into the patient and subsequently aligning the distal portion of the lead by orienting the indicator at an entry port of the introducer sheath.

Abstract: Disclosed herein are compounds of formula I: or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are also disclosed.

Abstract: Provided herein are RET kinase inhibitors according to the formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods for their use in the treatment of diseases that can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders. A, R1, n, X1, X2, X3, X4, and R2 have the meanings given in the specification.

Abstract: An apparatus for forming a plasma may include one or more coupling ports to accept a radiofrequency (RF) current. The apparatus may additionally include one or more coupling structures which may include one or more conductive loops to permit the RF current to conduct from at least a first portion of the one or more coupling ports to at least a second port of the one or more coupling ports. The one or more conductive loops may each be configured to exhibit a first value of inductance in the absence of the plasma and to exhibit a second value of inductance in the presence of the plasma. The one or more coupling structures may each include a reactive element, in which each reactive element is coupled to a corresponding one of the one or more conductive loops so as to form a corresponding number of coupling structures. Each RF coupling structure may have a resonant frequency that increases in response to the presence of the plasma.

Abstract: There is described a building automation system comprising a control center and an adapter for providing integration of subsystems. The adapter facilitates communications between the control center and a subsystem of the building automation system. A subsystem library of the control center receives an object model associated with the subsystem from the user interface. An extraction tool of the control center generates output information based on the object model. The control center is mapped to the adapter, so that a thing description may be communicated there between. The thing description includes a description of instances hosted by the adapter and representing the object model. An auto discovery component of the control center creates instances of the object model based on the thing description and addresses properties of the object model. The building automation system utilizes the instances and the addresses to manage the subsystem associated with the object model.

Abstract: An RF antenna is configured, when powered, to inductively generate plasma in a process region of a chamber, including: an array of parallel conductive lines that are oriented along a plane, the array including a first conductive line, a second conductive line, a third conductive line, and a fourth conductive line; wherein the first and second conductive lines are adjacent, wherein the second and third conductive lines are adjacent, and wherein the third and fourth conductive lines are adjacent; wherein when the RF antenna is powered, current flow in the adjacent first and second conductive lines occurs in an opposite direction, current flow in the adjacent second and third conductive lines occurs in a same direction, current flow in the adjacent third and fourth conductive lines occurs in an opposite direction.

Abstract: An apparatus for generating plasma, including a quadrupole antenna having a center region and an outer region and configured to be disposed over a dielectric window of a plasma chamber. The quadrupole antenna including a first coil defining a first SDA and a second coil defining a second SDA, the first coil being in a nested arrangement within the second coil. The nested arrangement places a turn of the first coil to be adjacent to a corresponding turn of the second coil as the first and second coils spiral from the center region to the outer region of the quadrupole antenna. Adjacent turns of each of the first and second coils are horizontally separated from one another by a distance when disposed over the dielectric window.

Abstract: An apparatus for generating plasma, including a quadrupole antenna having a center region and an outer region and configured to be disposed over a dielectric window of a plasma chamber. The quadrupole antenna including a first coil defining a first SDA and a second coil defining a second SDA, the first coil being in a nested arrangement within the second coil. The nested arrangement places a turn of the first coil to be adjacent to a corresponding turn of the second coil as the first and second coils spiral from the center region to the outer region of the quadrupole antenna. Adjacent turns of each of the first and second coils are horizontally separated from one another by a distance when disposed over the dielectric window.

Abstract: There is described a building automation system comprising a control center and an adapter for providing integration of subsystems. The adapter facilitates communications between the control center and a subsystem of the building automation system. A subsystem library of the control center receives an object model associated with the subsystem from the user interface. An extraction tool of the control center generates output information based on the object model. The control center is mapped to the adapter, so that a thing description may be communicated there between. The thing description includes a description of instances hosted by the adapter and representing the object model. An auto discovery component of the control center creates instances of the object model based on the thing description and addresses properties of the object model. The building automation system utilizes the instances and the addresses to manage the subsystem associated with the object model.

Abstract: RF isolation for power circuitry includes one or more ferrite cages surrounding a pair of coils, one coil connected to power input, and the other coil connected to a load such as a heater. The ferrite cage provides universal isolation for the coils, avoiding the necessity of specially tuned filters or more complicated coil arrangements. A pair of dielectric discs support respective coils. In one aspect, the ferrite cage is constituted by ferrite pieces which fan out from a central portion of the dielectric discs and are connected at an outer periphery of the dielectric discs, and at the central portion of the dielectric discs. In one aspect, the fanned-out ferrite pieces comprises either manganese-zinc or magnesium-zinc ferrites, and the ferrite pieces connecting the fanned-out ferrite pieces comprise nickel-zinc ferrites.

Abstract: An apparatus for generating plasma, including a quadrupole antenna having a center region and an outer region and configured to be disposed over a dielectric window of a plasma chamber. The quadrupole antenna including a first coil defining a first SDA and a second coil defining a second SDA, the first coil being in a nested arrangement within the second coil. The nested arrangement places a turn of the first coil to be adjacent to a corresponding turn of the second coil as the first and second coils spiral from the center region to the outer region of the quadrupole antenna. Adjacent turns of each of the first and second coils are horizontally separated from one another by a distance when disposed over the dielectric window.

Abstract: RF isolation for power circuitry includes one or more ferrite cages surrounding a pair of coils, one coil connected to power input, and the other coil connected to a load such as a heater. The ferrite cage provides universal isolation for the coils, avoiding the necessity of specially tuned filters or more complicated coil arrangements. A pair of dielectric discs support respective coils. In one aspect, the ferrite cage is constituted by ferrite pieces which fan out from a central portion of the dielectric discs and are connected at an outer periphery of the dielectric discs, and at the central portion of the dielectric discs. In one aspect, the fanned-out ferrite pieces comprises either manganese-zinc or magnesium-zinc ferrites, and the ferrite pieces connecting the fanned-out ferrite pieces comprise nickel-zinc ferrites.

Abstract: Various methods are provided to address the need for improved load balancing. In a one method, a packet loss is determined (101) for traffic sent between a first network node and a second network node. The determined packet loss is then used to determine (103) whether to perform load balancing. In another method, a first network node receives a request from a neighboring network node for a current loading status of the first network node. The first network node sends to the neighboring network node an indication of a backhaul loading level of the first network node.

Abstract: Various methods are provided to address the need for improved load balancing. In a one method, a packet loss is determined (101) for traffic sent between a first network node and a second network node. The determined packet loss is then used to determine (103) whether to perform load balancing. In another method, a first network node receives a request from a neighboring network node for a current loading status of the first network node. The first network node sends to the neighboring network node an indication of a backhaul loading level of the first network node.

Abstract: A system and method of cleaning a substrate includes a megasonic chamber that includes a transducer and a substrate. The transducer is being oriented toward the substrate. A variable distance d separates the transducer and the substrate. The system also includes a dynamically adjustable RF generator that has an output coupled to the transducer.

Abstract: A method of supporting access to a selected Internet Protocol (IP) multimedia application via an IP Multimedia Subsystem (IMS) is provided for a roaming mobile node (MN)—i.e., user equipment (UE)served by a wireless telecommunications system. The method includes: includes establishing a first IP tunnel between the UE and a local access gateway of a visited network, the first tunnel being anchored at the local access gateway; establishing a second IP tunnel between the UE and a home gateway of a home network, the second tunnel being anchored at the home gateway; receiving data packets at the local access gateway for the UE; filtering the packets received at the local access gateway to suitably classify corresponding traffic into one of a plurality of data flows supported within the first tunnel at varying Quality of Service (QoS) levels; and filtering the received packets.

Abstract: A substrate preparation system includes a proximity head configured to be positioned near a surface of the substrate to deliver a solution to the surface of the substrate. The proximity head includes a plurality of inlets for delivering the solution and a plurality of outlets for removing a portion of the solution from the surface of the substrate. The surface of the substrate maintains a remaining portion of the solution as a coherent film after the proximity head is scanned over the surface of the substrate. The coherent film is configured to be cured. The remaining portion of the solution acts on the surface of the substrate and binds particulates present on the surface of the substrate as the coherent film cures.

Abstract: A method of supporting access to a selected Internet Protocol (IP) multimedia application via an IP Multimedia Subsystem (IMS) is provided for a roaming mobile node (MN)—i.e., user equipment (UE) (10)—served by a wireless telecommunications system. The method includes: establishing a first IP tunnel (20) between the UE (10) and a local access gateway (30) of a visited network in which the UE (10) is roaming, the first tunnel (20) being anchored at the local access gateway (30); establishing a second IP tunnel (22?) between the UE (10) and a home gateway (40?) of a home network to which the UE (10) belongs, the second tunnel (22?) being anchored at the home gateway (40?); receiving data packets at the local access gateway (30) for the UE (10); filtering the packets received at the local access gateway (30) to suitably classify corresponding traffic into one of a plurality of data flows (20a, 20b, . . .

Abstract: A method of dynamically adjusting a RF generator to an instantaneous resonant frequency of a transducer includes providing an RF input signal from an oscillator to the RF generator and measuring a supply voltage applied to the RF generator. A peak voltage in the RF generator is also measured. A frequency control signal is produced when the peak voltage is not equal to a selected ratio of the supply voltage. The frequency control signal is applied to a frequency control input of the oscillator.

Abstract: A system and method of generating RF includes an RF generator, a variable DC power supply, and a comparator. The RF generator has an RF output coupled to an input of the transducer. The variable DC power supply has a control input and a DC output coupled to the RF generator. The comparator includes a first input coupled to a set point control signal, a second input coupled to the RF generator RF output, and a control signal output coupled to a voltage control input on the variable DC power supply.