Patents by Inventor Thomas W. Myers

Thomas W. Myers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20140295500
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: May 20, 2014
    Publication date: October 2, 2014
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140295499
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: March 31, 2014
    Publication date: October 2, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140234909
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140227743
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: April 16, 2014
    Publication date: August 14, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers, Nancy J. Schoenbrunner, Joseph San Filippo
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140220639
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: March 28, 2014
    Publication date: August 7, 2014
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: FRED REICHERT, KEITH BAUER, THOMAS W. MYERS
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140212883
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20140212929
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8765436
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: July 1, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8765435
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: July 1, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA polymerases with improved activity
    Patent number: 8759063
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: June 24, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8741617
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: June 3, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-match discrimination
    Patent number: 8735121
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: May 27, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8735120
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: May 27, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers, Nancy J. Schoenbrunner, Joseph San Filippo
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8722379
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: May 13, 2014
    Assignee: Roche Medical Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 8722380
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: May 13, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3'-mismatch discrimination
    Patent number: 8715991
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: May 6, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20140051126
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: December 5, 2012
    Publication date: February 20, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • HEV Assay
    Publication number: 20130280697
    Abstract: A method of simultaneously amplifying genotypes 1, 2, 3 and/or 4 of HEV is disclosed comprising amplifying the genotypes 1, 2, 3 and/or 4 of HEV with one single none-degenerate forward primer partially overlapping the 5?UTR region of HEV and at least one reverse primer. Also disclosed are related methods comprising a probe, and kits for the detection of genotypes 1, 2, 3 and/or 4 of HEV.
    Type: Application
    Filed: April 17, 2013
    Publication date: October 24, 2013
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Hermann Leying, Thomas W. Myers, Nicolas Newton, Eberhard Russmann, Joseph San Filippo, Nancy Schoenbrunner, Heike Wilts, Xiaoning Wu, Karen K. Y. Young, Dirk Zimmermann
  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20130196382
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: July 26, 2012
    Publication date: August 1, 2013
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Fred Reichert, Shawn Suko
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20120208240
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: July 11, 2011
    Publication date: August 16, 2012
    Applicant: Roche Molecurlar Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers