Abstract: An agricultural machine for the combined application of seed and granulate on an agricultural area includes a separating device, a portioning device, and a control device. The separating device has a rotationally drivable separating element for separating seed grains and the portioning device has a rotationally drivable portioning element for producing granulate portions. The control device matches the rotational movements of the separating element and the portioning element to each other to implement a predetermined depositing relationship of the seed grains and the granulate portions on the agricultural area.

Abstract: Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Abstract: An agricultural application machine for the combined application of seed and granulate on an agricultural area includes a separating device a portioning device, and a control device. The separating device has a rotationally drivable separating element for separating seed grains and the portioning device has a rotationally drivable portioning element for producing granulating portions. The control device matches the rotational movements of the separating element and the portioning element to each other to implement a predetermined depositing relationship of the seed grains and the granulating portions on the agricultural area.

Abstract: A method is described for tracking happy moments of a user wearing a hearing device comprising at least one microphone and at least one classifier configured to detect specific states of the user or of the user's environment based on a sensor signal indicative of the user's mood.

Abstract: The invention relates to a method for regulating the throwing behavior of a centrifugal spreader for fertilizer and to a centrifugal spreader configured therefor. According thereto, a target throwing distance is determined for a target working width. Furthermore, one of several rotational speed levels is selected for at least one spreading disc to approximate the actual throwing distance to the target throwing distance. Finally, an adapted target throwing angle for regulating an actual throwing angle is determined from the actual throwing distance (WW1) and counteracts in a compensatory manner a deviation from the target working width caused be the difference between the actual throwing distance and the target throwing distance. Continuous regulation of the throwing distance then becomes unnecessary, resulting in more stable regulation of the overall throwing behavior.

Abstract: Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Abstract: A computer-implemented method for designing a digital PCR (dPCR) experiment is provided. The method includes receiving, from a user, a selection of optimization type. The optimization type may be maximizing the dynamic range, minimizing the number of substrates including reaction sites needed for the experiment, determining a dilution factor, or determining the lower limit of detection, for example. The method further includes receiving, from the user, a precision measure for an experiment, and a minimum concentration of a target in a reaction site for the experiment. The method also includes determining a set of dPCR experiment design factors for the experiment based on the optimization type. The set of dPCR experiment design factors is then displayed to the user.

Abstract: A method for determining false positives calls in a biological data plot is provided. The method includes identifying a first data cluster as non-amplification data points within the biological data plot and identifying a second data cluster as wild-type positives within the biological data plot. The method further includes estimating a position in the biological data plot of a center of the first and second data clusters. The method further includes determining, for each data point within the first data cluster, a probability of belonging to the first data cluster and determining, for each data point within the second data cluster, a probability of belonging to the second data cluster. The method includes applying a probability threshold for each data point within the first and second data cluster to identify false positives.

Abstract: A computer-implemented method for designing a digital PCR (dPCR) experiment is provided. The method includes receiving, from a user, a selection of optimization type. The optimization type may be maximizing the dynamic range, minimizing the number of substrates including reaction sites needed for the experiment, determining a dilution factor, or determining the lower limit of detection, for example. The method further includes receiving, from the user, a precision measure for an experiment, and a minimum concentration of a target in a reaction site for the experiment. The method also includes determining a set of dPCR experiment design factors for the experiment based on the optimization type. The set of dPCR experiment design factors is then displayed to the user.

Abstract: A system for analyzing biological data, comprising: a storage configured to store a plurality of data files containing biological data obtained from a plurality of devices; a server configured to: host a plurality of applications, each configured to be implemented on the server and to provide analysis, manipulation, comparison, visualization, or a combination thereof, of the biological data included in the data files, wherein the plurality of applications allow a user to analyze different data files related to the same sample and compare the results of the analysis.

Abstract: Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Abstract: A hearing device configured to be worn by a user includes a microphone, an accelerometer, and a processor. The microphone detects an audio signal. The accelerometer outputs accelerometer data associated with the hearing device. The processor is configured to 1) identify a music feature of the audio signal, the music feature indicating that the audio signal includes music content, 2) identify a movement feature of the accelerometer data, the movement feature representative of movement by the user while the microphone detects the audio signal, 3) determine a similarity measure between the music feature and the movement feature, and 4) perform, based on the similarity measure, an operation with respect to a sound processing program executable by the processor.

Abstract: A hearing device configured to be worn by a user includes a microphone, an accelerometer, and a processor. The microphone detects an audio signal. The accelerometer outputs accelerometer data associated with the hearing device. The processor is configured to 1) identify a music feature of the audio signal, the music feature indicating that the audio signal includes music content, 2) identify a movement feature of the accelerometer data, the movement feature representative of movement by the user while the microphone detects the audio signal, 3) determine a similarity measure between the music feature and the movement feature, and 4) perform, based on the similarity measure, an operation with respect to a sound processing program executable by the processor.

Abstract: In one exemplary embodiment, a method for validating an instrument is provided. The method includes receiving amplification data from a validation plate to generate a plurality of amplification curves. The validation plate includes a sample of a first quantity and a second quantity, and each amplification curve includes an exponential region. The method further includes determining a set of fluorescence thresholds based on the exponential regions of the plurality of amplification curves and determining, for each fluorescence threshold of the set, a first set of cycle threshold (Ct) values of amplification curves generated from the samples of the first quantity and a second set of Ct values of amplification curves generated from the samples of the second quantity. The method includes calculating if the first and second quantities are sufficiently distinguishable based on Ct values at each of the plurality of fluorescence thresholds.

Abstract: There is provided a method of operating a hearing device (10, 11) to be worn by a user, comprising: defining a plurality of hearing device services and assigning to each hearing device service a service access confirmation level selected from a plurality of hierarchically structured service access confirmation levels; providing an access software platform for enabling third party service access to the hearing device services; providing at least one application program adapted to provide a third party service to the hearing device, each application program adapted to utilize the access software platform and at least one of the hearing device services; providing a manufacturer access service for approving or denying access to the hearing device for each of the application programs depending on whether or not approval for the respective service access confirmation level(s) has been previously obtained.

Abstract: The invention relates to a method for regulating the throwing behavior of a centrifugal spreader for fertilizer and to a centrifugal spreader configured therefor. According thereto, a target throwing distance is determined for a target working width. Furthermore, one of several rotational speed levels is selected for at least one spreading disc to approximate the actual throwing distance to the target throwing distance. Finally, an adapted target throwing angle for regulating an actual throwing angle is determined from the actual throwing distance (WW1) and counteracts in a compensatory manner a deviation from the target working width caused be the difference between the actual throwing distance and the target throwing distance. Continuous regulation of the throwing distance then becomes unnecessary, resulting in more stable regulation of the overall throwing behavior.

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

Abstract: There is provided a method of operating a hearing device (10, 11) to be worn by a user, comprising: defining a plurality of hearing device services and assigning to each hearing device service a service access confirmation level selected from a plurality of hierarchically structured service access confirmation levels; providing an access software platform for enabling third party service access to the hearing device services; providing at least one application program adapted to provide a third party service to the hearing device, each application program adapted to utilize the access software platform and at least one of the hearing device services; providing a manufacturer access service for approving or denying access to the hearing device for each of the application programs depending on whether or not approval for the respective service access confirmation level(s) has been previously obtained.

Abstract: A method for calibrating a biological instrument is provided. The method comprises the steps of acquiring an image of at least one biological sample array, determining a first region of interest within the image, wherein the first region of interest comprises a first plurality of locations on the at least one biological array; and identifying within the first region of interest, a plurality of image elements associated with each of the first plurality of locations on the at least one biological array.

Abstract: A method for improving image quality is provided. The method includes receiving image data of a substrate, wherein the image data is generated by imaging the substrate, and an image is generated from the image data. The method further includes generating a background representation from a background noise portion of the image, wherein the background portion includes signal information undesired for further processing and generating a background subtracted image by subtracting the background representation from the image. In this way, a separate background image is not needed to subtract the background from the image including the regions-of-interest to improve image quality.