Patents by Inventor Thomas Zierke

Thomas Zierke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6114358
    Abstract: Compounds of the formula ##STR1## where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: September 5, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Dorit Baucke, Udo Lange, Helmut Mack, Werner Seitz, Thomas Zierke, Hans Wolfgang Hoffken, Wilfried Hornberger
  • Patent number: 6030972
    Abstract: Compounds of the formula ##STR1## where A, B, D, R.sup.1 and R.sup.2 have the meanings stated in the description, are described. The compounds are suitable for controlling diseases.The novel compounds are prepared via compounds of the formulaH.sub.2 N--CH.sub.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: February 29, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Joachim Bohm, Hans Wolfgang Hoffken, Wilfried Hornberger, Stefan Koser, Helmut Mack, Thomas Pfeiffer, Werner Seitz, Thomas Zierke
  • Patent number: 5965700
    Abstract: A process for preparing pentapeptides of the formula I ##STR1## where A and R.sup.1 -R.sup.3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II ##STR2## where R.sup.1 and R.sup.2 have the abovementioned meanings, and eliminating the group --NR.sup.1 R.sup.2 by hydrolysis where appropriate the peptide obtained in this way.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: October 12, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Amberg, Harald Bernard, Ernst Buschmann, Andreas Haupt, Bernd Janssen, Ulrich Karl, Andreas Kling, Stefan Muller, Kurt Ritter, Thomas Zierke
  • Patent number: 5945543
    Abstract: A process for preparing .alpha.-(N,N-dialkylamino) carboxamides of the formula I ##STR1## where the substituents have the stated meanings, comprises reacting the corresponding free acids with primary or secondary amines in the presence of anhydrides of an alkanephosphonic acid.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: August 31, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Ernst Buschmann, Thomas Zierke
  • Patent number: 5932567
    Abstract: Thrombin inhibitors of the formula ##STR1## where R.sup.1, A, B and D have the meaning indicated in the description, and intermediates for the preparation thereof are described.The compounds I are suitable for controlling diseases.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: August 3, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Werner Seitz, Helmut Mack, Thomas Zierke, Hans-Joachim Bohm, Hans Wolfgang Hoffken, Stefan Koser, Thomas Pfeiffer, Wilfried Hornberger
  • Patent number: 5886147
    Abstract: Compounds of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
    Type: Grant
    Filed: November 6, 1996
    Date of Patent: March 23, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Amberg, Harald Bernard, Ernst Buschmann, Andreas Haupt, Lothar Janitschke, Bernd Janssen, Ulrich Karl, Andreas Kling, Stefan Muller, Bernd de Potzolli, Kurt Ritter, Marco Thyes, Thomas Zierke
  • Patent number: 5864012
    Abstract: The compound Me.sub.2 Val--Val--MeVal--Pro--Pro--NHBzl.multidot.HCl is described. It is prepared from Z--Val--Val--MeVal--Pro--OR.sup.1 where Z and R.sup.1 have the meanings stated in the description. The compound shows antineoplastic activity.
    Type: Grant
    Filed: November 4, 1996
    Date of Patent: January 26, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Amberg, Harald Bernard, Ernst Buschmann, Andreas Haupt, Lothar Janitschke, Bernd Janssen, Ulrich Karl, Andreas Kling, Stefan Muller, Bernd de Potzolli, Kurt Ritter, Marco Thyes, Thomas Zierke
  • Patent number: 5852051
    Abstract: Compounds of the formula I ##STR1## in which R.sup.1, A and B have the meanings stated in the description, and the preparation thereof are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: June 5, 1997
    Date of Patent: December 22, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Joachim Bohm, Stefan Koser, Helmut Mack, Thomas Pfeiffer, Werner Seitz, Hans Wolfgang Hoffken, Wilfried Hornberger, Thomas Zierke
  • Patent number: 5807984
    Abstract: Novel peptides of the formulaA--B--D--E--F--L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: September 15, 1998
    Assignee: BASF Aktienegesellschaft
    Inventors: Andreas Kling, Bernd Janssen, Wilhelm Amberg, Andreas Haupt, Kurt Ritter, Ernst Buschmann, Harald Bernard, Stefan Muller, Thomas Zierke, Teresa Barlozzari, Monika de Arruda, Simon Robinson
  • Patent number: 5523462
    Abstract: Cyclohexenone derivatives I ##STR1## The cyclohexenone derivatives I are suitable as herbicides and for regulating plant growth.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: June 4, 1996
    Assignee: BASF Aktiengesellschaft
    Inventors: Juergen Kast, Thomas Zierke, Matthias Bratz, Ulf Misslitz, Norbert Meyer, Andreas Landes, Wilhelm Rademacher, Karl-Otto Westphalen, Helmut Walter
  • Patent number: 5364834
    Abstract: Oxime ether derivatives of the general formula IR.sup.1 R.sup.2 C.dbd.NO--CH.sub.2 --COOR.sup.3 Iwhere R.sup.1 and R.sup.2 independently of one another are each hydrogen or C.sub.1 -C.sub.6 -alkyl or, together with the carbon atom to which they are bonded, are C.sub.5 - or C.sub.6 -cycloalkyl and R.sup.3 is hydrogen or C.sub.1 -C.sub.6 -alkyl, are used for bioregulation in plants.
    Type: Grant
    Filed: February 24, 1992
    Date of Patent: November 15, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Juergen Kirchner, Oskar Schmidt, Klaus Grossmann, Wilhelm Rademacher, Michael Hepp, Thomas Zierke
  • Patent number: 5268517
    Abstract: The preparation of Z-1,2-diarylallyl chlorides of the general formula I ##STR1## in which R.sup.1 and R.sup.2, independently of one another, are hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy or a substituted aromatic radical, and n and m are 1, 2 or 3, by dehydrating chlorohydrins of the formula II ##STR2## in which the radicals are as defined above, at up to 50.degree. C. in an inert ether or carboxylic acid ester as solvent and in the presence of a carboxylic anhydride and an organic or inorganic acid, the conversion thereof into azolylmethyloxiranes, and novel intermediates are described.
    Type: Grant
    Filed: December 7, 1992
    Date of Patent: December 7, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Reiner Kober, Rainer Seele, Heinz Isak, Eckhard Hichmann, Norbert Goetz, Thomas Zierke
  • Patent number: 5196433
    Abstract: Compounds of the Formula ##STR1## where R is alkyl or cycloalkyl,X,Y,Z are hydrogen, halogen, alkyl, alkoxy, alkoximino, haloalkyl, cyano, niro or substituted or unsubstituted phenyl or phenoxy,W is a single bond or one of the groups --CH.sub.2 --, --CH(CH.sub.3)-- or --CH.sub.2 CH.sub.2 -- andn is 0 or 1, andplant-tolerated acid addition salts thereof, and fungicides containing these compounds.
    Type: Grant
    Filed: June 4, 1992
    Date of Patent: March 23, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Zierke, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5194441
    Abstract: R.sup.2 is additionally H when X+Y=--O--CH(W.sup.3 R.sup.3)--O--, --O--CH(O--W.sup.4 R.sup.4)--O-- or --O--C(W.sup.3 R.sup.3)(O--W.sup.4 R.sup.4)--O-- and W.sup.2 =direct bond,except cis-1-(2,4-dichlorophenyl)-2-(pryid-3-yl)-1,2-epoxypropane, trans-1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)-1,2-epoxypropane, 1-(2,4- dichlorophenyl)-2-(pryid-3-yl)-1,2-epoxybutane and 2,4-dichloro- .alpha.[1-hydroxy-1-(pyrid-3-yl)-ethyl]-benzyl methanesulfonate,and the N-oxides and the plant-tolerated mineral acid salts and metal complexes of I.The compounds I are suitable as fungicides.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: March 16, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Zierke, Bernhard Zipperer, Hubert Sauter, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5174997
    Abstract: Compounds of the formula 1 ##STR1## where R is unsubstituted or substituted cycloalkyl or cycloalkenyl,X, Y and Z are hydrogen, halogen, alkyl, alkoxy, alkoximino, haloalkyl, cyano, nitro or unsubstituted or substituted phenyl or phenoxy,W is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- andn is 0 or 1, and the plant-tolerated acid-addition salts thereof, and fungicides containing these compounds are described.
    Type: Grant
    Filed: January 24, 1991
    Date of Patent: December 29, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Zierke, Thomas Kuekenhoehner, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5175167
    Abstract: Hetarylalkenes of the general formula I ##STR1## where Ar is hetaryl,A is C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.3 -C.sub.8 -cycloalkyl-C.sub.1 -C.sub.3 -alkyl or unsubstituted or monosubstituted, disubstituted or trisubstituted aryl or aralkyl, ##STR2## Z is whereR is hydrogen, C.sub.2 -C.sub.4 -acyl, unsubstituted or substituted benzoyl, C.sub.1 -C.sub.4 -alkylsulfonyl, unsubstituted or C.sub.1 -C.sub.4 -alkyl-substituted phenylsulfonyl or a radical R.sup.1,R.sup.1 is C.sub.1 -C.sub.4 -alkyl or unsubstituted or substituted phenyl or benzyland Hal is fluorine, chlorine, bromine or iodine,and B is unsubstituted or substituted mononuclear or dinuclear aryl, aralkyl or hetaryl,and their N-oxides and addition salts, the preparation of these substances, intermediates for this purpose and the preparation thereof, fungicides containing hetarylalkenes and a corresponding method for controlling harmful fungi.
    Type: Grant
    Filed: February 8, 1991
    Date of Patent: December 29, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Zipperer, Manfred Lauer, Norbert Goetz, Thomas Zierke, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5159117
    Abstract: A process for preparing .alpha.,.alpha.-dialkoxy ketones of the formula I ##STR1## where R.sup.1 and R.sup.2 are each, independently of one another, hydrogen, C.sub.1 -C.sub.20 -alkyl, C.sub.3 -C.sub.20 -cycloalkyl, C.sub.4 -C.sub.30 -cycloalkylakyl, C.sub.9 -C.sub.30 -alkylcycloalkyl, unsubstituted or C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 -alkoxy-, halogen-, C.sub.1 -C.sub.4 -haloalkyl-, C.sub.1 -C.sub.4 -haloalkoxy-, phenyl-, phenoxy-, halophenyl-, halophenoxy- and/or cyano-substituted aryl, C.sub.7 -C.sub.20 -aralkyl or heterocyclyl,R.sup.2 is also ##STR2## R.sup.3 and R.sup.4 are each, independently of one another, C.sub.1 -C.sub.20 -alkyl, C.sub.3 -C.sub.20 -cycloalkyl, aryl, C.sub.7 -C.sub.20 -arylalkyl, or together are an unsubstituted or C.sub.1-C.sub.4 -alkyl- substituted C.sub.2 -C.sub.7 -alkylene chain andR.sup.5 is R.sup.1 or together with R.sup.1 is an unsubstituted or C.sub.1 -C.sub.4 -alkyl-substituted C.sub.2 -C.sub.
    Type: Grant
    Filed: August 20, 1991
    Date of Patent: October 27, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Guenter Wegner, Stefan Karbach, Hubert Smuda, Eckhard Hickmann, Reiner Kober, Rainer Seele, Thomas Zierke
  • Patent number: 5156669
    Abstract: 5-(1,2,4-Triazol-1-yl-methyl)-isoxazolines I ##STR1## where R.sup.1 and R.sup.2 are each H, alkoxyalkyl, haloalkyl, alkyl, cycloalkylalkyl, phenylalkyl, naphthylalkyl, cycloalkyl, phenyl, naphthyl or hetaryl, where the aryl and hetaryl moieties of the stated substituents may furthermore carry an unsubstituted or halogen-substituted phenyl or phenoxy radical or up to 3 of the following radicals: halogen, CN, NO.sub.2, alkyl, haloalkyl or alkoxy, and the salts and metal complexes of I are suitable as fungicides and for regulating plant growth.
    Type: Grant
    Filed: April 9, 1991
    Date of Patent: October 20, 1992
    Inventors: Thomas Zierke, Thomas Kuekenhoehner, Juergen Frank, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5093046
    Abstract: Ethereal solutions of arylmethylmagnesium halidesAr--CH.sub.2 --Mg--Hal I(where Ar is unsubstituted or substituted aryl and Hal is Cl or Br) are prepared by the Grignard method from an arylmethyl halide IIAr--CH.sub.2 --Hal IIand magnesium in an ether IIItert-butyl--O--R III(where R is C.sub.1 -C.sub.3 -alkyl) as solvent.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: March 3, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Reiner Kober, Rainer Seele, Thomas Zierke, Heinz Isak, Stefan Karbach, Guenter Wegner
  • Patent number: 5081142
    Abstract: Compounds of the formula I ##STR1## where Ar is unsubstituted or substituted phenyl, pyridyl, thienyl or napthyl,R.sup.1 is hydrogen or CN,R.sup.2 is unsubstituted or substituted aryl, hetaryl, alkyl or cycloalkyl, or is unsubstituted or substituted alkenyl or alkynyl,x is CH.sub.2, O or S andn is 0 or 1,their plant-tolerated acid addition salts and metal complexes, and fungicides and growth regulators containing these compounds.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: January 14, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Hubert Sauter, Thomas Zierke, Wolfgang Reuther, Ulf Baus, Gisela Lorenz, Eberhard Ammermann