Patents by Inventor Tian Lu

Tian Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130214143
    Abstract: A method and system for detecting ratios and amounts of isotopes of noble gases. The method and system is constructed to be able to measure noble gas isotopes in water and ice, which helps reveal the geological age of the samples and understand their movements. The method and system uses a combination of a cooled discharge source, a beam collimator, a beam slower and magneto-optic trap with a laser to apply resonance frequency energy to the noble gas to be quenched and detected.
    Type: Application
    Filed: February 16, 2012
    Publication date: August 22, 2013
    Inventors: Zheng-Tian LU, Shiu-Ming Hu, Wei Jiang, Peter Mueller
  • Publication number: 20130217133
    Abstract: The present invention provides an auto-developing and regularly-weighted protein molecular weight marker kit, comprising: (a) a plurality of recombinant proteins having formula (I), (B)m-A-(C)n??(I), wherein A is a polypeptide of SEQ ID NO: 1, B and C are independently any mutually identical or different polypeptides with the value of molecular weight being a multiple of 5, and m and n is independently 0 or any integer larger than 0; and (b) one or more solvents for stabilizing the recombinant proteins. The present invention also provides a method for preparing the auto-developing and regularly-weighted protein molecular weight marker kit.
    Type: Application
    Filed: February 22, 2012
    Publication date: August 22, 2013
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Tian-Lu Cheng, Chiu-Min Cheng
  • Patent number: 8507207
    Abstract: The invention provides a recombinant nucleotide sequence, including the sequence of SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 or SEQ ID No. 4, wherein the recombinant nucleotide sequence encodes an anti-polyethylene glycol recombinant single chain membrane antibody.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: August 13, 2013
    Assignee: Kaohsiung Medical University
    Inventors: Tian-Lu Cheng, Steve R. Roffler, Kuo-Hsiang Chuang
  • Publication number: 20120015380
    Abstract: In this invention, anti-PEG antibodies or anti-methoxyl-PEG (anti-CH3O-PEG) antibodies were expressed on cell surface which can collocate with a biotinylated anti-PEG antibody (AGP4-Biotin) or biotinylated PEG (PEG-Biotin) to develop a cell-based sandwich ELISA or a cell-based competition ELISA, respectively. Both of these two methods could sensitively quantify free PEG and PEG-modified macromolecules (proteins, nanoparticles and liposomes) as sensitive as nano-gram level.
    Type: Application
    Filed: February 22, 2011
    Publication date: January 19, 2012
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Tian-Lu Cheng, Steven R. Roffler, Kuo-Hsiang Chuang, Ssu-Jung Lu
  • Publication number: 20110064651
    Abstract: The invention provides a recombinant nucleotide sequence, including the sequence of SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 or SEQ ID No. 4, wherein the recombinant nucleotide sequence encodes an anti-polyethylene glycol recombinant single chain membrane antibody.
    Type: Application
    Filed: April 26, 2010
    Publication date: March 17, 2011
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Tian-Lu Cheng, Steve R. Roffler, Kuo-Hsiang Chuang
  • Publication number: 20100173629
    Abstract: A method for facilitating inter-PLMN (Public Land Mobile Network) roaming comprises a plurality of operations. A home PLMN of a caller's wireless communication device performs an operation for determining that the caller's wireless communication device is not located in the home PLMN and, in response to determining that the caller's wireless communication device is not located in the home PLMN, an operation for facilitating a call routing service in a Service Control Point (SCP) of the home PLMN. The call routing service causes a call originated by the caller's wireless communication device while roaming in a visited PLMN to be routed back to a Gateway Mobile Switching Center (GMSC) of the home PLMN thereby allowing the home PLMN to have control over the roaming caller originated call and to have limited dependency on the visited PLMN.
    Type: Application
    Filed: August 21, 2007
    Publication date: July 8, 2010
    Inventors: Tian Lu, Zhao Bruce, Sha Ping, Lin Eddy
  • Publication number: 20080176225
    Abstract: A recombinant DNA construct is provided and includes a first DNA fragment encoding a ?-glucuronidase and a second DNA fragment encoding a membrane anchoring domain. The ?-glucuronidase may be a human ?-glucuronidase or a mouse ?-glucuronidase. In one embodiment, an expression vector for delivering a gene of interest or portion thereof into a host cell includes a DNA sequence for the gene of interest, a first DNA fragment encoding a ?-glucuronidase, and a second DNA fragment encoding a membrane anchoring domain. In another embodiment, a method of introducing a gene of interest or portion thereof into a host cell is provided, including introducing into the host cell a recombinant DNA construct.
    Type: Application
    Filed: January 18, 2007
    Publication date: July 24, 2008
    Inventors: Steve ROFFLER, Tian-Lu Cheng, Yu-Cheng Su
  • Patent number: 7398280
    Abstract: Disclosed are a method and system for manufacturing integrated circuits meeting special customer requirements with multiple subcontractors in remote locations. The disclosed manufacturing automation execution system detects customer special requirements and keeps track of such special requirements throughout the manufacturing process. The system accesses various databases to retrieve relevant data for determining and issuing electronic die release orders to subcontractors in remote locations. The disclosed method and system enable a broader range of services in manufacturing integrated circuits.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: July 8, 2008
    Assignee: Altera Corporation
    Inventors: Mun Tutt Chin, Weng Hong Kwan, Gary John Rangel, Siew Tian Lu
  • Publication number: 20080050729
    Abstract: A method for detecting cancer cells. A chemical luminescence reaction is used to obtain a result image. The result image is analyzed through a weighting process to a value of each gene. By doing do, a cancer can be precisely diagnosed.
    Type: Application
    Filed: October 25, 2006
    Publication date: February 28, 2008
    Applicant: Kaohsiung Medical University
    Inventors: Shiu-Ru Lin, Tian-Lu Cheng
  • Patent number: 7320791
    Abstract: A novel anti-polyethylene glycol monoclonal antibody and its preparation are disclosed. Such an antibody can be used for determining polyethylene glycol concentration in vitro or accelerating the clearance of a polyethylene glycol containing compound from the blood circulation in the human body thereby reducing the toxicity associated with the polyethylene glycol containing conjugate. The antibody is particularly useful in cancer therapy where the therapeutic agent is selectively delivered to the tumor by increasing the tumor/blood ratio of the polyethylene glycol containing compound.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: January 22, 2008
    Assignee: Academia Sinica
    Inventors: Steve Roffler, Tian-Lu Cheng, Pin-Yi Wu
  • Publication number: 20060068396
    Abstract: The present invention is a method for a biochip detecting limited cells. The present invention comprises steps of: obtaining a nylon membrane chip having required nucleotide fragments arranged in a dot matrix way by using a manual spotter; naturally drying by heat and fixing the nucleotide fragments on the nylon membrane chip by a rapid nucleic acid cross-linker when preparing a chip; collecting some normal whole blood to be linearly amplified; synthesizing required amount of cDNA by a reverse transcription to obtain a marker as a probe; processing labeling, hybridization and post-hybridization to the chip and the marker; processing chemical color reaction; and automatically analyzing the result image after the chemical color reaction. Accordingly, a gene biochip operation technology platform with low cost, easy operation and high efficiency is obtained.
    Type: Application
    Filed: September 24, 2004
    Publication date: March 30, 2006
    Inventors: Shiu-Ru Lin, Tian-Lu Cheng, Yi-Fang Chen, Chan-Han Wu
  • Publication number: 20060039912
    Abstract: A non-therapeutic method of producing antibodies that bind adipose tissues in a target animal in need of the antibodies for modulating the content of adipose tissues in the target animal, the method comprising the steps of (a) preparing an antigen from the adipose tissues of a source animal, (b) administering the antigen to an egg-laying animal to cause production of the antibodies, and (c) obtaining the antibodies from eggs of the egg-laying animal wherein the source animal and the egg-laying animal belong to different species.
    Type: Application
    Filed: June 5, 2003
    Publication date: February 23, 2006
    Applicant: Walcom Animal Science (1.P.4) Limited
    Inventors: Francis Chi, Tian Lu
  • Publication number: 20050089549
    Abstract: A fish feeding composition for improving the growth and/or health of fish comprises cysteamine or salts thereof and from 1 to 80 wt % of a carrier. The fish feeding composition is preferably added to a basal feed and then fed to the fish. Use of such a feed increases body weight and reduces death due to disease and adverse living conditions.
    Type: Application
    Filed: February 20, 2003
    Publication date: April 28, 2005
    Inventors: Francis Chi, Qin Wen, Tian Lu
  • Publication number: 20050051103
    Abstract: The present invention relates generally to the use of cysteamine or a cysteamine-containing composition for (I) increasing the yield and/or quality of eggs produced by fowls, (ii) preferentially promoting growth rate of female fowls over male fowls and/or (iii) preferentially promoting development of breast muscles of fowls over development of muscles other than the breast muscles. The invention also relates to a method and cysteamine-containing feed of raising fowls, and a method of preparing such feed.
    Type: Application
    Filed: July 12, 2002
    Publication date: March 10, 2005
    Inventors: Francis Chi, Qin Wen, Tian Lu
  • Publication number: 20050027015
    Abstract: The use of cysteamine, a salt thereof or a composition containing cysteamine or a salt thereof for improving lactation of lactating animals.
    Type: Application
    Filed: September 18, 2002
    Publication date: February 3, 2005
    Inventors: Francis Chi, Qin Wen, Tian Lu
  • Publication number: 20050004075
    Abstract: A method of preparing a composition for regulating animal growth comprising the steps of preparing cysteamine or its salt, and mixing the cysteamine or its salt with cyclodextrin or its derivative in a reactor.
    Type: Application
    Filed: July 6, 2004
    Publication date: January 6, 2005
    Applicant: WALCOM ANIMAL SCIENCE (I.P.2) LIMITED
    Inventors: Francis Chi, Qin Wen, Tian Lu
  • Publication number: 20040014156
    Abstract: A novel anti-polyethylene glycol monoclonal antibody and its preparation are disclosed. Such an antibody can be used for determining polyethylene glycol concentration in vitro or accelerating the clearance of a polyethylene glycol containing compound from the blood circulation in the human body thereby reducing the toxicity associated with the polyethylene glycol containing conjugate. The antibody is particularly useful in cancer therapy where the therapeutic agent is selectively delivered to the tumor by increasing the tumor/blood ratio of the polyethylene glycol containing compound.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 22, 2004
    Applicant: Academia Sinica
    Inventors: Steve Roffler, Tian-Lu Cheng, Pin-Yi Wu
  • Patent number: 6617118
    Abstract: A novel anti-polyethylene glycol monoclonal antibody and its preparation are disclosed. Such an antibody can be used for determining polyethylene glycol concentration in vitro or accelerating the clearance of a polyethylene glycol containing compound from the blood circulation in the human body thereby reducing the toxicity associated with the polyethylene glycol containing conjugate. The antibody is particularly useful in cancer therapy where the therapeutic agent is selectively delivered to the tumor by increasing the tumor/blood ratio of the polyethylene glycol containing compound.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: September 9, 2003
    Assignee: Academia Sinica
    Inventors: Steve Roffler, Tian-Lu Cheng, Pin-Yi Wu
  • Patent number: 6596849
    Abstract: A novel anti-polyethylene glycol monoclonal antibody and its preparation are disclosed. Such an antibody can be used for determining polyethylene glycol concentration in vitro or accelerating the clearance of a polyethylene glycol containing compound from the blood circulation in the human body thereby reducing the toxicity associated with the polyethylene glycol containing conjugate. The antibody is particularly useful in cancer therapy where the therapeutic agent is selectively delivered to the tumor by increasing the tumor/blood ratio of the polyethylene glycol containing compound.
    Type: Grant
    Filed: March 7, 2000
    Date of Patent: July 22, 2003
    Assignee: Academia Sinica
    Inventors: Steve Roffler, Tian-Lu Cheng, Pin-Yi Wu
  • Publication number: 20010028881
    Abstract: A novel anti-polyethylene glycol monoclonal antibody and its preparation are disclosed. Such an antibody can be used for determining polyethylene glycol concentration in vitro or accelerating the clearance of a polyethylene glycol containing compound from the blood circulation in the human body thereby reducing the toxicity associated with the polyethylene glycol containing conjugate. The antibody is particularly useful in cancer therapy where the therapeutic agent is selectively delivered to the tumor by increasing the tumor/blood ratio of the polyethylene glycol containing compound.
    Type: Application
    Filed: March 16, 2001
    Publication date: October 11, 2001
    Applicant: Academia Sinica
    Inventors: Steve Roffler, Tian-Lu Cheng, Pin Yi Wu