Patents by Inventor Tibor Szabo

Tibor Szabo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Patent number: 7713992
    Abstract: The present invention relates to adenosine A3 receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and their salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Pyrazole derivatives and use thereof as orexin receptor antagonists
    Patent number: 7659298
    Abstract: The present invention relates to the orexin receptor antagonists compounds of the general formula (I) as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic application thereof.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: February 9, 2010
    Assignee: sanofi-aventis
    Inventors: Michel Aletru, Peter Aranyi, Maria Balogh, Sandor Batori, Judit Bence, Philippe Bovy, Zoltan Kapui, Endre Mikus, Claudie Namane, Christophe Philippo, Tibor Szabo, Zsuzsanna Tomoskozi, Katalin Urban-Szabo
  • Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
    Patent number: 7655663
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: February 2, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Compounds useful for DPP-IV enzyme inhibition
    Patent number: 7652021
    Abstract: The present invention relates to the novel compounds of the general formula (I) possessing dipeptidyl peptidase IV enzyme inhibitory activity, pharmaceutical compositions thereof, methods of using said compounds, processes for their preparation and intermediates of the general formulae (II), (IV), (V), (VII), (VIII) and (IX).
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: January 26, 2010
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Zoltan Kapui, Edit Susan, Tibor Szabo, Katalin Urban-Szabo, Marton Varga
  • New amino-alkyl-amide derivatives as CCR3 receptor ligands
    Publication number: 20080293745
    Abstract: The invention relates to a compound of the general formula (I), as defined herein which is useful for the treatment of a pathology in a patient wherein a CCR3 receptor plays a role in the development of the pathology, and pharmaceutical preparations containing such compound. The invention is also directed to a process for preparing the compound of the general formula (I), and intermediate useful in the preparation.
    Type: Application
    Filed: March 18, 2008
    Publication date: November 27, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Agnes PAPPNE BEHR, Zoltan KAPUI, Peter ARANYI, Sandor BATORI, Veronika BARTANE BODOR, Lajos T. NAGY, Mihalyne Santa, Marton VARGA, Gyorgy FERENCZY, Endre MIKUS, Katalin URBAN-SZABO, Judit VARGANE SZEREDI, Tibor SZABO, Erzsebet WALCZ
  • New amino-alkyl-amide derivatives as CCR3 receptor ligands
    Publication number: 20080280961
    Abstract: The invention relates to a compound of the general formula (I), as defined herein which is useful for the treatment of a pathology in a patient wherein a CCR3 receptor plays a role in the development of the pathology, and pharmaceutical preparations containing such compound. The invention is also directed to a process for preparing the compound of the general formula (I), and intermediate useful in the preparation.
    Type: Application
    Filed: March 19, 2008
    Publication date: November 13, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Agnes PAPPNE BEHR, Zoltan KAPUI, Peter ARANYI, Sandor BATORI, Veronika BARTANE BODOR, Lajos T. NAGY, Mihalyne Santa, Marton VARGA, Endre MIKUS, Katalin URBAN-SZABO, Judit VARGANE SZEREDI, Tibor SZABO, Edit SUSAN, Marianna KOVACS
  • New amino-alkyl-amide derivatives as CCR3 receptor ligands
    Publication number: 20080280963
    Abstract: The invention relates to a compound of the general formula (I), as defined herein which is useful for the treatment of a pathology in a patient wherein a CCR3 receptor plays a role in the development of the pathology, and pharmaceutical preparations containing such compound. The invention is also directed to a process for preparing the compound of the general formula (I), and intermediate useful in the preparation.
    Type: Application
    Filed: March 19, 2008
    Publication date: November 13, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Agnes PAPPNE BEHR, Zoltan KAPUI, Peter ARANYI, Sandor BATORI, Veronika BARTANE BODOR, Lajos T. NAGY, Mihalyne Santa, Marton VARGA, Endre MIKUS, Katalin URBAN-SZABO, Judit VARGANE SZEREDI, Tibor SZABO, Edit SUSAN, Marianna KOVACS
  • FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY
    Publication number: 20080161310
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: March 5, 2008
    Publication date: July 3, 2008
    Applicant: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Triazolo-Quinolin Derivatives Useful as Adenosine Receptor Ligands
    Publication number: 20080146604
    Abstract: The present invention relates to adenosine A3 receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and their salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 19, 2008
    Applicant: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Patent number: 7365089
    Abstract: The present invention relates to adenosine A3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and theirs salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: April 29, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Compounds
    Patent number: 7348327
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: March 25, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20070043037
    Abstract: The present invention relates to the orexin receptor antagonists of the general formula (I), which are selective to orexin I receptors.
    Type: Application
    Filed: August 10, 2006
    Publication date: February 22, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Peter ARANYI, Maria BALOGH, Sandor BATORI, Judit BENCE, Michel FINET, Zoltan KAPUI, Christophe PHILIPPO, Tibor SZABO, Zoltan SZLAVIK, Zsuzsanna TOMOSKOZI, Katalin URBAN-SZABO, Olivier VENIER
  • PYRAZOLE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20070021459
    Abstract: The present invention relates to the orexin receptor antagonists compounds of the general formula (I) as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic application thereof.
    Type: Application
    Filed: June 21, 2006
    Publication date: January 25, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Michel ALETRU, Peter ARANYI, Maria BALOGH, Sandor BATORI, Judit BENCE, Philippe BOVY, Zoltan KAPUI, Endre MIKUS, Claudie NAMANE, Christophe PHILIPPO, Tibor SZABO, Zsuzsanna TOMOSKOZI, Katalin URBAN-SZABO
  • New compounds useful for DPP-IV enzyme inhibition
    Publication number: 20060276487
    Abstract: The present invention relates to the novel compounds of the general formula (I) possessing dipeptidyl peptidase IV enzyme inhibitory activity, pharmaceutical compositions thereof, methods of using said compounds, processes for their preparation and intermediates of the general formulae (II), (IV), (V), (VII), (VIII) and (IX).
    Type: Application
    Filed: February 28, 2006
    Publication date: December 7, 2006
    Applicant: Sanofi-aventis
    Inventors: Peter Aranyi, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Zoltan Kapui, Edit Susan, Tibor Szabo, Katalin Urban-Szabo, Marton Varga
  • Process for the production of beraprost and its salts
    Patent number: 7005527
    Abstract: The present invention relates to a new process for the preparation of beraprost of formula (I) using new intermediates.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: February 28, 2006
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Tibor Szabo, Jozsef Bodi, Gyuia Dalmadi, Zsusanna Baloghnekardos, Zoltan Szevfrenyi
  • Compounds
    Publication number: 20050153973
    Abstract: Heterocyclic amides useful as inhibitors of dipeptylpeptidase-IV (DPP-IV) enzyme, process for the preparation thereof and intermediates therefore.
    Type: Application
    Filed: June 11, 2003
    Publication date: July 14, 2005
    Inventors: Peter Aranyl, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos Nagy, Katalin Urban-Szabo, Marton Varga
  • Compounds
    Publication number: 20050130981
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: March 4, 2003
    Publication date: June 16, 2005
    Inventors: Peter Aranyl, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos Nagy, Katalin Urban-Szabo, Marton Varga
  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Publication number: 20050124648
    Abstract: The present invention relates to adenosine A-3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and theirs salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Application
    Filed: December 17, 2002
    Publication date: June 9, 2005
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hadju, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Process for the production of beraprost and its salts
    Publication number: 20040209945
    Abstract: The present invention relates to a new process for the preparation of beraprost of formula (I) using new intermediates.
    Type: Application
    Filed: April 1, 2004
    Publication date: October 21, 2004
    Inventors: Tibor Szabo, Jozsef Bodi, Gyuia Dalmadi, Zsusanna Baloghnekardos, Zoltan Szevfrenyi
  • HIGH PURITY (1R,2S,4R)-(?)-2-[(2?-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7 -TRI-[METHYL]-BICYCLO [2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF AND A PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE
    Patent number: 6624201
    Abstract: The invention relates to high purity (1R,2S,4R)-(−)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2′-{N,N-dimethylamino}-ethyl)]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: September 23, 2003
    Assignee: Orion Corporation
    Inventors: Gyula Lukács, Gyula Simig, Tibor Mezei, Zoltán Budai, Márta Porcs-Makkay, György Krasznai, Kálmán Nagy, Györgyi Donáth Vereczkey, Tibor Szabó, Norbert Németh, János Szulágyi