Patents by Inventor Tieno Germann

Tieno Germann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Sulfonamide Compounds
    Publication number: 20100324009
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 23, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted Sulfonamide Compounds
    Publication number: 20100317644
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Method of measuring the activity of G(alpha)i- or G(alpha)o-coupled receptors using Ca influx in cells
    Patent number: 7829300
    Abstract: A method of measuring the activation or deactivation of G(alpha)i- or G(alpha)o-coupled receptors, and methods of identifying agonists or antagonists of such receptors.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: November 9, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Erik James Wade, Elke Janocha, Tieno Germann
  • Substituted Spiro-amide Compounds
    Publication number: 20100249095
    Abstract: Substituted spiro-amide compounds corresponding to formula I in which R5 through R8, D, X, Y and Z have defined meanings, processes for preparing such spiro-amide compounds, pharmaceutical compositions containing such compounds, and methods of using such spiro-amide compounds for treating and/or inhibiting disorders or disease states mediated at least in part by the bradykinin 1 receptor.
    Type: Application
    Filed: March 24, 2010
    Publication date: September 30, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Stefan Oberboersch, Michael Engels, Tieno Germann, Ruth Jostock, Christa Kneip
  • Substituted Spiroamide Compounds
    Publication number: 20100234340
    Abstract: Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: February 5, 2010
    Publication date: September 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Sulfonylated Tetrahydroazolopyrazines and their Use as Pharmaceuticals
    Publication number: 20100234387
    Abstract: Sulfonylated tetrahydroazolopyrazine compounds corresponding to the formula I wherein R1, R2a, R2b, R3a, R3b, R4, R8, R9a, R9b, R10, R11, A, B, W1, W2 and W3 have the meanings defined herein, pharmaceutical compositions containing such compounds, a method for the preparation of such compounds, and the use of such compounds for treating or inhibiting various types of pain and/or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: March 4, 2010
    Publication date: September 16, 2010
    Applicant: Gruenethal GmbH
    Inventors: Beatrix MERLA, Stefan Oberboersch, Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Michael Engels, Tieno Germann, Edward Bijsterveld
  • Substituted Indole Compounds
    Publication number: 20100222324
    Abstract: Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).
    Type: Application
    Filed: February 3, 2010
    Publication date: September 2, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Pyrimidine and Triazine Compounds
    Publication number: 20100173889
    Abstract: Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.
    Type: Application
    Filed: October 23, 2009
    Publication date: July 8, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Stefan Schunk, Melanie Reich, Kamila Hennig, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Disulfonamide Compounds
    Publication number: 20100152158
    Abstract: Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
    Type: Application
    Filed: November 6, 2009
    Publication date: June 17, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie REICH, Stefan Schunk, Ruth Jostock, Sabine Hees, Tieno Germann, Michael Franz-Martin Engels
  • Substituted Sulfonamide Compounds
    Publication number: 20090298812
    Abstract: Substituted sulfonamide compounds corresponding to the formula I processes for the preparation thereof, pharmaceutical compositions containing these compounds and the use of substituted sulfonamide compounds for the preparation of pharmaceutical compositions for treating pain and other conditions at least partly mediated via the bradykinin 1 receptor.
    Type: Application
    Filed: March 4, 2009
    Publication date: December 3, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Ruth Jostock, Klaus Schiene, Jean De Vry, Tieno Germann, Sabine Hees, Stefan Schunk, Melanie Reich
  • SUBSTITUTED SULFONAMIDE COMPOUNDS
    Publication number: 20090275558
    Abstract: Substituted sulfonamide compounds corresponding to formula I processes for the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds for treating and/or inhibiting pain or other conditions at least partly mediated by the bradykinin 1 receptor.
    Type: Application
    Filed: April 9, 2009
    Publication date: November 5, 2009
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie Reich, Ellen Klegraf, Stefan Oberboersch, Stefan Schunk, Ruth Jostock, Sabine Hees, Tieno Germann, Michael Engels
  • Substituted Sulfonamide Compounds
    Publication number: 20090264400
    Abstract: Substituted sulfonamide compounds corresponding to formula I: processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment and/or inhibition of pain and other conditions at least partly mediated by the bradykinin 1 receptor.
    Type: Application
    Filed: April 8, 2009
    Publication date: October 22, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Stefan Schunk, Michael Franz-Martin Engels, Ruth Jostock, Tieno Germann, Jean De Vry, Klaus Schiene, Sabine Hees
  • Substituted Sulfonamide Compounds
    Publication number: 20090264407
    Abstract: Substituted sulfonamide compounds corresponding to formula I: a process for their preparation, pharmaceutical compositions comprising such compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment of pain or other disorders or diseases that are mediated at least in part by B1R receptors.
    Type: Application
    Filed: April 8, 2009
    Publication date: October 22, 2009
    Applicant: GRUENENTHAL GmbH
    Inventors: Stefan OBERBOERSCH, Melanie REICH, Stefan SCHUNK, Michael ENGELS, Ruth JOSTOCK, Tieno GERMANN, Sabine HEES
  • Method of Measuring the Activity of G(alpha)i-or G(alpha)o-Coupled Receptors Using Ca2+ Influx in Cells
    Publication number: 20090136989
    Abstract: A method of measuring the activation or deactivation of G(alpha)i- or G(alpha)o-coupled receptors, and methods of identifying agonists or antagonists of such receptors.
    Type: Application
    Filed: December 16, 2008
    Publication date: May 28, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Erik James Wade, Elke Janocha, Tieno Germann
  • Substituted Sulfonamide Compounds
    Publication number: 20080249128
    Abstract: Substituted sulfonamide compounds with bradykinin receptor (B1R) modulating activity; processes for the preparation thereof, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or inhibit pain and/or other disorders and/or disease states.
    Type: Application
    Filed: October 16, 2007
    Publication date: October 9, 2008
    Applicant: GRUENENTHAL GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • SUBSTITUTED SULFONAMIDE COMPOUNDS
    Publication number: 20080153843
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: September 28, 2007
    Publication date: June 26, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie REICH, Stefan SCHUNK, Sabine HEES, Ruth JOSTOCK, Michael Franz-Martin ENGELS, Achim KLESS, Thomas CHRISTOPH, Klaus SCHIENE, Tieno GERMANN, Edward BIJSTERVELD
  • Piperidine-2,6-diones heterocyclically substituted in the 3-position
    Patent number: 7183274
    Abstract: Piperidine-2,6-diones heterocyclically substituted in the 3-position corresponding to formula I Also the production and use of such compounds in pharmaceutical formulations and related methods of treatment.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: February 27, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Heinrich Buschmann, Stefanie Frosch, Tieno Germann, Oswald Karl Zimmer, Fritz Theil
  • Method of measuring the activity of G(alpha)i- or G(alpha)o-coupled receptors using Ca2+ influx in cells
    Publication number: 20050277110
    Abstract: A method of measuring the activation or deactivation of G(alpha)i- or G(alpha)o-coupled receptors, and methods of identifying agonists or antagonists of such receptors.
    Type: Application
    Filed: June 3, 2005
    Publication date: December 15, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Erik Wade, Elke Janocha, Tieno Germann
  • Piperidine-2,6-diones heterocyclically substituted in the 3-position
    Publication number: 20050020581
    Abstract: Piperidine-2,6-diones heterocyclically substituted in the 3-position corresponding to formula I Also the production and use of such compounds in pharmaceutical formulations and related methods of treatment.
    Type: Application
    Filed: June 21, 2004
    Publication date: January 27, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Stefanie Frosch, Tieno Germann, Oswald Zimmer, Fritz Theil
  • Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives and related treatment methods
    Publication number: 20040192916
    Abstract: Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene compounds and processes for their production, the use thereof for producing pharmaceutical compositions, pharmaceutical compositions containing these compounds and methods of treatment using these compounds.
    Type: Application
    Filed: December 24, 2003
    Publication date: September 30, 2004
    Applicant: Gruenenthal GmbH
    Inventors: Heinrich Helmut Buschmann, Guenter Werner Englberger, Tieno Germann, Hagen-Heinrich Hennies, Corinna Maul, Bernd Sundermann, Joerg Holenz