Abstract: Binding members for sodium channel Nav1.7 and their use in medicine including for treatment of pain or epilepsy. Binding members comprise a fusion protein containing a Nav1.7-binding peptide, e.g., venom toxin peptide or knottin (“donor diversity scaffold domain”) inserted within an antibody variable domain (“recipient diversity scaffold domain”), and a partner domain (e.g., antibody variable domain), optionally wherein the partner domain enhances specificity of binding to Nav1.7 over other sodium channels.

Abstract: In certain aspects of the present disclosure, a computer-implemented includes generating a unique code for display on a managed device, and authorizing a manager device to selectively initiate at least one workflow on the managed device. The method includes, responsive to the manager device scanning the unique code, verifying the manager device is authorized. The method includes displaying on the manager device, based on verification that the manager device is authorized, an option corresponding to the at least one workflow. The method includes receiving, from the manager device, a selected workflow. The method includes, responsive to receiving the selected workflow, transmitting a message to a push notification server initiating the managed device to communicate with an MDM server. The method includes transmitting a command to the managed device causing performance of the selected workflow on the managed device. Systems and machine-readable media are also provided.

Abstract: A smoking article and a method for making a smoking article are provided.

Abstract: A smoking article and a method for making a smoking article are provided.

Abstract: In response to a query to a database, the identity of a slave machine which stores the requested data is resolved, and the query is parsed to identify one or more shards at the slave machine. Each shard corresponds to a partition of the requested data stored at the slave, and rows inside of the shard are respectively assigned a fixed-size local ID. Tasks corresponding to each shard are placed into a thread pool, and the threads are processed using the respective local IDs to obtain the requested data.

Abstract: A robotic vehicle can include a plurality of motors coupled to a plurality of gearboxes, each gearbox of the plurality of gearboxes configured to be rotated, a plurality of nested driveshafts coupled to the plurality of gearboxes and including at least a first driveshaft and a second driveshaft, and a plurality of appendages operably coupled to the plurality of gearboxes. A particular appendage of the plurality of appendages can be configured to be rotated in response to a rotational motion of the first driveshaft. The robotic vehicle can include a plurality of wheels coupled to the plurality of appendages and configured to rotate about a plurality of wheel axles. Each wheel of the plurality of wheels can be configured to cause the robotic vehicle to be transported across a contacting surface in response to the rotational motion of the second driveshaft.

Abstract: Embodiments of a data encryption and/or decryption technique are disclosed. In accordance with one example embodiment, a method may include enciphering a message, based at least in part, on a hierarchical symbol assignment system, and modifying an enciphering key signal value to modify a level of security of enciphering.

Abstract: A smoking article and a method for making a smoking article are provided.

Abstract: Smoking articles and a method for making a smoking article are provided.

Abstract: In response to a query to a database, the identity of a slave machine which stores the requested data is resolved, and the query is parsed to identify one or more shards at the slave machine. Each shard corresponds to a partition of the requested data stored at the slave, and rows inside of the shard are respectively assigned a fixed-size local ID. Tasks corresponding to each shard are placed into a thread pool, and the threads are processed using the respective local IDs to obtain the requested data.

Abstract: A robotic vehicle can include a plurality of motors coupled to a plurality of gearboxes, each gearbox of the plurality of gearboxes configured to be rotated, a plurality of nested driveshafts coupled to the plurality of gearboxes and including at least a first driveshaft and a second driveshaft, and a plurality of appendages operably coupled to the plurality of gearboxes. A particular appendage of the plurality of appendages can be configured to be rotated in response to a rotational motion of the first driveshaft. The robotic vehicle can include a plurality of wheels coupled to the plurality of appendages and configured to rotate about a plurality of wheel axles. Each wheel of the plurality of wheels can be configured to cause the robotic vehicle to be transported across a contacting surface in response to the rotational motion of the second driveshaft.

Abstract: Devices, systems, and methods for articulating elongate flexible structures such as catheters optionally include an array of fluid-expandable bodies such as balloons. The array can be formed using separate strings of balloons formed along single-lumen balloon tube material. The balloon strings can be twisted together to form a multi-channel bundle, or the balloon strings may be circumferentially separated, each extending axially. Regardless, the balloons along a common lumen may be aligned so as to bend the catheter in a desired lateral direction. The fluid-expandable bodies may include an elastomeric bladder with a fiber braid so that inflation of the bladder shortens the assembly and applies axial tension to articulate the catheter. The elongate flexible structures may be pre-biased so as to form a bend when in a relaxed configuration, with the structures being articulatable from the bend.

Abstract: A smoking article and a method for making a smoking article are provided.

Abstract: Devices, systems, and methods for articulating elongate flexible structures such as catheters optionally include an array of fluid-expandable bodies such as balloons. A user may alter a bend characteristic of the flexible structure by manually moving a handle of a pump. The pump may induce a flow of inflation fluid into a subset of the expandable bodies, and the resulting expansion can change a bend characteristic of the flexible structure. The pump may comprise a threaded syringe pump, one or more balloon that is manually compressed by movement of the handle (so that the balloon acts as a displacement pump), a multi-axis displacement pump (optionally with laterally offset piston-cylinder assemblies coupled to the handle to induce laterally offset bending of the flexible structure), or the like, providing easily-modulated articulation with a low-cost, light-weight, and/or at least partially disposable user interface.

Abstract: Smoking articles and a method for making a smoking article are provided.

Abstract: Graph-based detection systems and techniques are provided to identify potential malicious lateral movement paths. System and security events may be used to generate a network connection graph and detect remote file executions and/or other detections, for use in tracking malicious lateral movement across a computer network, such as a compromised computer network. Lateral movement determination across a computer network may be divided into two subproblems: forensic analysis and general detection. With forensic analysis, given a malicious node, possible lateral movement leading into or out of the node is identified. General detection identifies previously unknown malicious lateral movement on a network using a remote file execution detector, and/or other detectors, and a rare path anomaly detection algorithm.

Abstract: This invention relates to processes for obtaining a plurality of biomass measurements from one or more biological medium and to biomass sensing probes (1) for use in such methods.

Abstract: A smoking article and a method for making a smoking article are provided.

Abstract: Graph-based detection systems and techniques are provided to identify potential malicious lateral movement paths. System and security events may be used to generate a network connection graph and detect remote file executions and/or other detections, for use in tracking malicious lateral movement across a computer network, such as a compromised computer network. Lateral movement determination across a computer network may be divided into two subproblems: forensic analysis and general detection. With forensic analysis, given a malicious node, possible lateral movement leading into or out of the node is identified. General detection identifies previously unknown malicious lateral movement on a network using a remote file execution detector, and/or other detectors, and a rare path anomaly detection algorithm.

Abstract: A hybrid vehicle battery cell rebalancer for hybrid vehicles used to restore cell balance and improve performance while cooling and protecting the hybrid battery against damage from the rebalancing process. This may be accomplished by charging and/or discharging the battery cells in the hybrid battery pack at the same time while powering and controlling the vehicle's hybrid battery cooling fan.