Patents by Inventor Timothy Harrison

Timothy Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Design structure for final via designs for chip stress reduction
    Patent number: 7439170
    Abstract: A design structure to provide a package for a semiconductor chip that minimizes the stresses and strains that arise from differential thermal expansion in chip to substrate or chip to card interconnections. An improved set of design structure vias above the final copper metallization level that mitigate shocks during semiconductor assembly and testing. Other embodiments include design structures having varying micro-mechanical support structures that further minimize stress and strain in the semiconductor package.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: October 21, 2008
    Assignee: International Business Machines Corporation
    Inventors: Timothy Harrison Daubenspeck, Wolfgang Sauter, Jeffrey P. Gambino, David L. Questad
  • Gamma-secretase inhibitors
    Patent number: 7435748
    Abstract: Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: October 14, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Jose Luis Castro Pineiro, Ian James Collins, Timothy Harrison
  • Cyclic sulfamides for inhibition of gamma-secretase
    Patent number: 7427621
    Abstract: Compounds of formula I: inhibit the processing of AP by gamma-secretase, and hence are useful for treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: September 23, 2008
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Ian James Collins, Joanne Clare Hannam, Timothy Harrison, Andrew Madin, Mark Peter Ridgill
  • Cyclohexyl sulphones as gamma-secretase inhibitors
    Patent number: 7410964
    Abstract: Compounds of formula I: inhibit gamma-secretase and hence find use in treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: August 12, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Kevin Dinnell, Karl Richard Gibson, Timothy Harrison, Richard Alexander Jelley, Alan John Nadin, Paul Joseph Oakley, Andrew Pate Owens, Duncan Edward Shaw, Brian John Williams
  • Sulphones which modulate the action of gamma secretase
    Patent number: 7411004
    Abstract: Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: August 12, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Timothy Harrison, Paul Joseph Oakley, Martin Richard Teall
  • Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase
    Patent number: 7371771
    Abstract: Compounds of formula (I) are disclosed: wherein R4 is an alkenyl group of defined structure. The compounds inhibit gamma-secretase, and hence are useful for treatment of Alzheimer's disease.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: May 13, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Jose Luis Castro Pineiro, Joanne Claire Hannam, Timothy Harrison, Andrew Madin, Mark Peter Ridgill
  • Sulphonamido-substituted bridged bicycloalkyl derivatives
    Patent number: 7365196
    Abstract: A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: April 29, 2008
    Assignees: Merck Sharp & Dohme Ltd., Merck Frosst Canada & Co.
    Inventors: Patrice Charles Belanger, Ian James Collins, Joanne Claire Hannam, Timothy Harrison, Stephen John Lewis, Andrew Madin, Edward Giles McIver, Alan John Nadin, Joseph George Neduvelil, Mark Steven Shearman, Adrian Leonard Smith, Timothy Jason Sparey, Graeme Irvine Stevenson, Martin Richard Teall
  • Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase
    Publication number: 20080070895
    Abstract: Compounds of formula I are disclosed: in which X is a 5-membered heteroaryl ring and R is as defined herein. The compounds are inhibitors of the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: September 7, 2007
    Publication date: March 20, 2008
    Inventors: Ian Collins, Laura Cooper, Timothy Harrison, Linda Keown, Andrew Madin, Mark Ridgill
  • Cyclic sulfonamides for inhibition of gamma-secretase
    Patent number: 7342009
    Abstract: Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: March 11, 2008
    Assignee: Merck & Co., Inc.
    Inventors: Kevin Dinnell, Timothy Harrison, Alan John Nadin, Andrew Pate Owens, Duncan Edward Shaw, Brian John Williams
  • Cyclic sulfonamides for inhibition of gamma-secretase
    Publication number: 20080045515
    Abstract: Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: August 1, 2007
    Publication date: February 21, 2008
    Inventors: Kevin Dinnell, Timothy Harrison, Alan Nadin, Andrew Owens, Duncan Shaw, Brian Williams
  • Novel cyclohexyl sulphones
    Publication number: 20080045533
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 21, 2008
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan Nadin, Paul Oakley, Duncan Shaw, Martin Teall, Susannah Williams, Brian Williams
  • Cyclohexyl sulphones
    Patent number: 7304094
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: December 4, 2007
    Assignee: Merck Sharp + Dohme
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams, Brian John Williams
  • DUAL-SIDED CHIP ATTACHED MODULES
    Publication number: 20070267746
    Abstract: An electronic device and method of packaging an electronic device. The device including: a first substrate, a second substrate and an integrated circuit chip having a first side and an opposite second side, a first set of chip pads on the first side and a second set of chip pads on the second side of the integrated circuit chip, chip pads of the first set of chip pads physically and electrically connected to corresponding substrate pads on the first substrate and chip pads of the second set of chip pads physically and electrically connected to substrate pads of the substrate.
    Type: Application
    Filed: May 16, 2006
    Publication date: November 22, 2007
    Inventors: Kerry Bernstein, Timothy Dalton, Timothy Harrison Daubenspeck, Jeffrey Peter Gambino, Mark David Jaffe, Christopher David Muzzy, Wolfgang Sauter, Edmund Sprogis, Anthony Kendall Stamper
  • Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase
    Patent number: 7282513
    Abstract: Compounds of formula I are disclosed: in which X is a 5-membered heteroaryl ring and R is as defined herein. The compounds are inhibitors of the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 16, 2007
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Ian James Collins, Laura Catherine Cooper, Timothy Harrison, Linda Elizabeth Keown, Andrew Madin, Mark Peter Ridgill
  • (4, 5, 6, 7-Tetrahydro-1-H-Indol-7-Yl) Acetic Acid Derivatives for Treatment of Alzheimer's Disease
    Publication number: 20070232678
    Abstract: Compounds of formula I: are disclosed. The compounds are useful in treating or preventing diseases associated with deposition of A? in the brain.
    Type: Application
    Filed: May 6, 2005
    Publication date: October 4, 2007
    Inventors: Michela Bettati, Ian Churcher, Victoria Doughty, Timothy Harrison, Emanuela Nizi, Adam Smith
  • Sulphones which modulate the action of gammasecretase
    Publication number: 20070213329
    Abstract: Novel sulphones of Formula I are disclosed: wherein A completes a 4-7 membered ring optionally comprising up to two heteroatoms. The compounds modulate the action of ?-secretase and are therefore useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: April 23, 2007
    Publication date: September 13, 2007
    Inventors: Jose Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan Nadin, Paul Oakley, Andrew Owens, Duncan Shaw, Martin Teall, Susannah Williams, Brian Williams
  • Chip underfill in flip-chip technologies
    Patent number: 7256503
    Abstract: A semiconductor structure and method for forming the same. The semiconductor structure includes (a) a substrate and (b) a chip which includes N chip solder balls, N is a positive integer, and the N chip solder balls are in electrical contact with the substrate. The semiconductor structure further includes (c) first, second, third, and fourth corner underfill regions which are respectively at first, second, third, and fourth corners of the chip, and sandwiched between the chip and the substrate. The semiconductor structure further includes (d) a main underfill region sandwiched between the chip and the substrate. The first, second, third, and fourth corner underfill regions, and the main underfill region occupy essentially an entire space between the chip and the substrate. A corner underfill material of the first, second, third, and fourth corner underfill regions is different from a main underfill material of the main underfill region.
    Type: Grant
    Filed: February 27, 2006
    Date of Patent: August 14, 2007
    Assignee: International Business Machines Corporation
    Inventors: Timothy Harrison Daubenspeck, Jeffrey Peter Gambino, Christopher David Muzzy, Wolfgang Sauter, David L. Questad
  • Gamma-secretase inhibitors
    Publication number: 20070088063
    Abstract: Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease.
    Type: Application
    Filed: December 14, 2006
    Publication date: April 19, 2007
    Inventors: Jose Castro Pineiro, Ian Collins, Timothy Harrison
  • Sulphonamides for control of beta-amyloid production
    Patent number: 7205434
    Abstract: There is disclosed a novel class of sulphonamido-substituted bridged bicycloalkyl derivatives comprising a substitute on the bridgehead position. The compounds modulate the production of the ?-amyloid precursor protein, and hence are useful in the treatment of Alzheimer's Disease.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: April 17, 2007
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Joanne Clare Hannam, Timothy Harrison, Andrew Madin, Timothy Jason Sparey
  • Gamma-secretase inhibitors
    Patent number: 7183303
    Abstract: Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: February 27, 2007
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Jose Luis Castro Pineiro, Ian James Collins, Timothy Harrison