Abstract: The present disclosure relates to an automated peritoneal dialysis (APD) system using gravity to deliver fluid from one or more source dialysate bags to the patient as the destination. The present disclosure further relates to a drain container arrangement for receiving and storing spent dialysis effluent from a patient, wherein the drain containers include self-opening valves activated when the containers are arranged together, and the valves are self-sealing when the containers are disconnected from one another.

Abstract: Implementations described and claimed herein provide an underwater vehicle includes a vehicle body having a frame enclosed by a fairing. The vehicle body extends between a proximal end and a distal end and defining an interior. A nose is disposed at the proximal end of the vehicle body. The nose has a tow system configured to move between a tow position and a stow position. A propulsion system is disposed at the distal end of the vehicle body. The propulsion system includes a plurality of control fins and a thruster. A power distribution system is housed in the interior of the vehicle body. The power distribution system includes a first power system housed in a first pressure vessel and a second power system housed in a second pressure vessel. The first pressure vessel is isolated from the second pressure vessel.

Abstract: Surgical assemblies which reduce stress on a patient lower extremity while facilitating surgical procedures are disclosed. A surgical table extension is disclosed for positioning lower extremities. The table extension comprises a limb manipulator, a base, a platform support, and a perineal post. In another aspect, a surgical table extension comprises a brace assembly which contacts a patient foot, ankle, lower leg, and thigh. The brace assembly is connected to a limb manipulator, enabling the lower extremity to be rotated and manipulated. Rotation forces are applied to both the foot and the thigh, reducing stress on the patient knee.

Abstract: A method for selecting spectator viewpoints in volumetric video presentations of live events includes receiving a plurality of video streams depicting an event occurring in a venue, wherein the plurality of video streams are provided to a processor by a plurality of cameras which are geographically distributed within the venue, identifying an initial position of a target that is present in the venue, based on an analysis of the plurality of video streams, compositing the plurality of video streams to produce a first volumetric video traversal of the live event that follows the target through the venue, predicting a future position of the target in the venue at a future point in time, based in part on a current position of the target, and sending an alert to a display device that is streaming a volumetric video presentation of the event, wherein the alert indicates the future position of the target.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, CY, Cz, R1, R2, R3, R4, R2a, Ry, Rz, and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, Cy, Cz, R1, R2, R3, R4, R2a, Ry, Rz, and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: The invention includes remote-participation of a medical device manufacturing company representative in a medical procedure, whereby the device representative uses a variety of components to track and monitor devices in an operating room in “real-time,” while checking on device status and advising a surgeon through Wearable Video Technology rather than being physically present in the operating room. A system allows for a remote surgeon to advise surgeons, prepares for surgeries, chooses and tracks implant devices, evaluates and reports on device implantation, calibration and performance, evaluates surgeries and staff, prepares for and concludes procedures, trains medical staff members, performs billing functions, performs legal compliance functions, performs inventory restocking functions, and various other functions.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, Cy, Cz, R1, R2, R3, R4, R2a, Ry, Rz and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: A method for selecting spectator viewpoints in volumetric video presentations of live events includes receiving a plurality of video streams depicting an event occurring in a venue, wherein the plurality of video streams are provided to a processor by a plurality of cameras which are geographically distributed within the venue, identifying an initial position of a target that is present in the venue, based on an analysis of the plurality of video streams, compositing the plurality of video streams to produce a first volumetric video traversal of the live event that follows the target through the venue, predicting a future position of the target in the venue at a future point in time, based in part on a current position of the target, and sending an alert to a display device that is streaming a volumetric video presentation of the event, wherein the alert indicates the future position of the target.

Abstract: A method for selecting spectator viewpoints in volumetric video presentations of live events includes receiving a plurality of video streams depicting an event occurring in a venue, wherein the plurality of video streams are provided to a processor by a plurality of cameras which are geographically distributed within the venue, identifying an initial position of a target that is present in the venue, based on an analysis of the plurality of video streams, compositing the plurality of video streams to produce a first volumetric video traversal of the live event that follows the target through the venue, predicting a future position of the target in the venue at a future point in time, based in part on a current position of the target, and sending an alert to a display device that is streaming a volumetric video presentation of the event, wherein the alert indicates the future position of the target.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, Cy, Cz, R1, R2, R3, R4, R2a, Ry, Rz and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: A fuel control valve assembly that includes a ball bearing assembly and retainer assembly for a mixture control valve assembly and idle control valve assembly in use with general aviation fuel injector servos is disclosed. The assembly desirably reduces friction and wear on the components of the fuel control valve assembly.

Abstract: Aspects of the subject disclosure may include, for example, a device that includes a processing system and a memory that stores executable instructions that causes the device to perform operations including acquiring audiovisual data from a plurality of cameras focused on an event; recognizing an object in the audiovisual data; identifying key points on the object; determining a type of analytical information concerning movement of the key points; and providing a point-of-view (PoV) rendering from the audiovisual data to a viewer at a display interface, wherein the PoV rendering includes the analytical information. Other embodiments are disclosed.

Abstract: A method for selecting spectator viewpoints in volumetric video presentations of live events includes receiving a plurality of video streams depicting an event occurring in a venue, wherein the plurality of video streams are provided to a processor by a plurality of cameras which are geographically distributed within the venue, identifying an initial position of a target that is present in the venue, based on an analysis of the plurality of video streams, compositing the plurality of video streams to produce a first volumetric video traversal of the live event that follows the target through the venue, predicting a future position of the target in the venue at a future point in time, based in part on a current position of the target, and sending an alert to a display device that is streaming a volumetric video presentation of the event, wherein the alert indicates the future position of the target.

Abstract: A fuel control valve assembly that includes a ball bearing assembly and retainer assembly for a mixture control valve assembly and idle control valve assembly in use with general aviation fuel injector servos is disclosed. The assembly desirably reduces friction and wear on the components of the fuel control valve assembly.

Abstract: A conical scanning method and system is provided for orienting a spacecraft with respect to a source. The system includes a spacecraft and an incidence angle sensor secured to the spacecraft to sense a signal from a source. The incidence angle sensor has a boresight that is canted with respect to the principal axis. A processor communicates with actuators on the spacecraft to adjust an attitude of the spacecraft based on information received from the incidence angle sensor and to thereby align a principal axis of the spacecraft with a direction from the spacecraft to the source. The method and system can also rely on information received from source presence sensors. The source may be the Sun, or a non-solar signal source.

Abstract: A fuel control valve assembly that includes a ball bearing assembly and retainer assembly for a mixture control valve assembly and idle control valve assembly in use with general aviation fuel injector servos is disclosed. The assembly desirably reduces friction and wear on the components of the fuel control valve assembly.

Abstract: The present invention facilitates the remote-participation of a medical device manufacturing company representative in a medical procedure, whereby the device representative coordinates the surgery through audio-visual technology and electronic identifier devices. In the proposed system, the device manufacturing company representative serves as a Surgical Engineer™. The Surgical Engineer uses a variety of audio visual devices and electronic identifiers, as well as an Internet application and at least one server and at least one database, to track and monitor devices in a medical facility in “real-time,” while checking on device status and advising medical staff through Wearable Video Technology rather than being physically present in the operating room.

Abstract: A conical scanning method and system is provided for orienting a spacecraft with respect to a source. The system includes a spacecraft and an incidence angle sensor secured to the spacecraft to sense a signal from a source. The incidence angle sensor has a boresight that is canted with respect to the principal axis. A processor communicates with actuators on the spacecraft to adjust an attitude of the spacecraft based on information received from the incidence angle sensor and to thereby align a principal axis of the spacecraft with a direction from the spacecraft to the source. The method and system can also rely on information received from source presence sensors. The source may be the Sun, or a non-solar signal source.