Abstract: A system, method and implantable medical for providing switched power while providing transcutaneous telemetry communication with an implanted medical device having an internal power source. An electronics module is adapted to supply the therapeutic output to the patient. A telemetry module is configured for transcutaneous telemetry communication. The telemetry module obtains power from the telemetry signal during transcutaneous telemetry communication.

Abstract: A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques.

Abstract: An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor.

Abstract: An implantable medical device includes a hermetically sealed housing and a first light emitting diode (LED) enclosed within the housing configured to detect light corresponding to a selected light wavelength. A conductive element extends from the LED for carrying a current signal corresponding to the light detected by the LED, the intensity of the detected light being correlated to a change in a physiological condition in a body fluid volume or a tissue volume proximate the LED.

Abstract: A housing for an implantable medical device includes a first portion formed from a first material and a second portion formed from a second material. The first material and the second material comprise titanium and the first material has a higher resistivity than the second material.

Abstract: An implantable medical device includes a housing comprising a titanium alloy selected from the group consisting of Ti-4.5Al-3V-2Fe-2Mo-0.15O, Ti-4Al-2.5V-1.5Fe-0.25O, Ti-6Al-2Sn-4Zr-2Mo, Ti-3Al-2.

Abstract: Storable implantable medical device assembly and container for an implantable device having a charging sub-assembly. The implantable medical device has therapeutic componentry and a rechargeable power source operatively coupled to the therapeutic componentry. The charging sub-assembly having an electro-chemical power source, such as a battery, and a charging circuit operatively coupled to the electro-chemical power source. The implantable medical device and the charging sub-assembly are co-located within the container. The charging circuit of the charging sub-assembly is operatively coupled to the chargeable power source within the container to charge the rechargeable power source while the implantable medical device remains in the container. The charging sub-assembly may use inductive coupling to charge the implantable device mimicking implantable device charging following implantation.

Abstract: An apparatus for collecting biological aerosols from an air sample is provided comprising an air intake assembly adapted to draw the air sample into the apparatus, a separation section coupled to the intake assembly and adapted to separate aerosol particles from the air sample, a capture section coupled to the separation section and adapted to transport the aerosol particles in a stream of liquid, and a hydrophobic membrane disposed between the separation section and the capture section and adapted to establish a controllable air/fluid boundary therebetween.

Abstract: Three fundamental and three derived aspects of the present invention are disclosed. The three fundamental aspects each disclose a process sequence that may be integrated in a full process. The first aspect, designated as “latent masking”, defines a mask in a persistent material like silicon oxide that is held abeyant after definition while intervening processing operations are performed. The latent oxide pattern is then used to mask an etch. The second aspect, designated as “simultaneous multi-level etching (SMILE)”, provides a process sequence wherein a first pattern may be given an advanced start relative to a second pattern in etching into an underlying material, such that the first pattern may be etched deeper, shallower, or to the same depth as the second pattern. The third aspect, designated as “delayed LOCOS”, provides a means of defining a contact hole pattern at one stage of a process, then using the defined pattern at a later stage to open the contact holes.

Abstract: Three fundamental and three derived aspects of the present invention are disclosed. The three fundamental aspects each disclose a process sequence that may be integrated in a full process. The first aspect, designated as “latent masking”, defines a mask in a persistent material like silicon oxide that is held abeyant after definition while intervening processing operations are performed. The latent oxide pattern is then used to mask an etch. The second aspect, designated as “simultaneous multi-level etching (SMILE)”, provides a process sequence wherein a first pattern may be given an advanced start relative to a second pattern in etching into an underlying material, such that the first pattern may be etched deeper, shallower, or to the same depth as the second pattern. The third aspect, designated as “delayed LOCOS”, provides a means of defining a contact hole pattern at one stage of a process, then using the defined pattern at a later stage to open the contact holes.

Abstract: An electrospray nozzle system is disclosed. The electrospray portion of the device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray. The nozzle system may be utilized alone or as part of a liquid chromatography system.

Abstract: An electrospray device is disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray.

Abstract: Three fundamental and three derived aspects of the present invention are disclosed. The three fundamental aspects each disclose a process sequence that may be integrated in a full process. The first aspect, designated as “latent masking”, defines a mask in a persistent material like silicon oxide that is held abeyant after definition while intervening processing operations are performed. The latent oxide pattern is then used to mask an etch. The second aspect, designated as “simultaneous multi-level etching (SMILE)”, provides a process sequence wherein a first pattern may be given an advanced start relative to a second pattern in etching into an underlying material, such that the first pattern may be etched deeper, shallower, or to the same depth as the second pattern. The third aspect, designated as “delayed LOCOS”, provides a means of defining a contact hole pattern at one stage of a process, then using the defined pattern at a later stage to open the contact holes.

Abstract: An electrospray device, a liquid chromatography device and an electrosprayliquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray.

Abstract: An electrospray device, a liquid chromatography device and an electrosprayliquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray.

Abstract: An electrospray nozzle system is disclosed. The electrospray portion of the device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray. The nozzle system may be utilized alone or as part of a liquid chromatography system.

Abstract: An electrospray device, a liquid chromatography device and an electrospray-liquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray.

Abstract: An implanted medical device (IMD) conserves power by discriminating received radio frequency (RF) signals between noise and data based on frequency. Data is processed while noise is attenuated. The IMD operates in a first, relatively low, power mode while not receiving the RF signals, in a second, higher, power mode responsive to receiving RF signals, and operates in still higher power mode when the RF signals' average frequency over a selected period is within a predetermined range. A receiver circuit receives RF signals and discriminates a data signal from noise based on average frequency of the RF signals over selected time periods. The receiver circuit operates in a power-conserving mode unless it receives RF signals, or otherwise operates in a relatively higher-power mode. The receiver transfers signals to a telemetry circuit that operates in a power-conserving mode until it receives a valid data signal to operate in higher power mode.

Abstract: Three fundamental and three derived aspects of the present invention are disclosed. The three fundamental aspects each disclose a process sequence that may be integrated in a full process. The first aspect, designated as “latent masking”, defines a mask in a persistent material like silicon oxide that is held abeyant after definition while intervening processing operations are performed. The latent oxide pattern is then used to mask an etch. The second aspect, designated as “simultaneous multi-level etching (SMILE)”, provides a process sequence wherein a first pattern may be given an advanced start relative to a second pattern in etching into an underlying material, such that the first pattern may be etched deeper, shallower, or to the same depth as the second pattern. The third aspect, designated as “delayed LOCOS”, provides a means of defining a contact hole pattern at one stage of a process, then using the defined pattern at a later stage to open the contact holes.

Abstract: An electrospray device, a liquid chromatography device and an electrospray-liquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface, a nozzle defined by a portion recessed from the ejection surface surrounding the exit orifice, and an electrode for application of an electric potential to the substrate to optimize and generate an electrospray; and, optionally, additional electrode(s) to further modify the electrospray.