Patents by Inventor Timothy J. Krieger

Timothy J. Krieger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMICROBIAL AND ANTI-INFLAMMATORY PEPTIDES
    Publication number: 20180289768
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Application
    Filed: December 7, 2017
    Publication date: October 11, 2018
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • Antimicrobial and anti-inflammatory peptides
    Patent number: 9872885
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 23, 2018
    Assignee: CARRUS CAPITAL CORPORATION
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • Antimicrobial cationic peptides and formulations thereof
    Patent number: 9227999
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: January 5, 2016
    Assignee: Carrus Capital Corporation
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • ANTIMICROBIAL AND ANTI-INFLAMMATORY PEPTIDES
    Publication number: 20150343015
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Application
    Filed: December 17, 2014
    Publication date: December 3, 2015
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • ANTIMICROBIAL CATIONIC PEPTIDES AND FORMULATIONS THEREOF
    Publication number: 20150087580
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Application
    Filed: November 26, 2014
    Publication date: March 26, 2015
    Applicant: Carrus Capital Corporation
    Inventors: Timothy J. KRIEGER, Patricia J. McNicol
  • Antimicrobial and anti-inflammatory peptides
    Patent number: 8933029
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: January 13, 2015
    Assignee: Carrus Capital Corporation
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • Antimicrobial cationic peptides and formulations thereof
    Patent number: 8927487
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: January 6, 2015
    Assignee: Carrus Capital Corporation
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • ANTIMICROBIAL CATIONIC PEPTIDES AND FORMULATIONS THEREOF
    Publication number: 20130296227
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Application
    Filed: June 7, 2013
    Publication date: November 7, 2013
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • Antimicrobial cationic peptides and formulations thereof
    Patent number: 8466102
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: June 18, 2013
    Assignee: Carrus Capital Corporation
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • ANTIMICROBIAL CATIONIC PEPTIDES AND FORMULATIONS THEREOF
    Publication number: 20120202735
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Application
    Filed: March 15, 2012
    Publication date: August 9, 2012
    Applicant: Carrus Capital Corporation
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • Antimicrobial cationic peptides and formulations thereof
    Patent number: 8138144
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: March 20, 2012
    Assignee: Carrus Capital Corporation
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • COMPOSITIONS AND METHODS FOR TREATING INFECTIONS USING CATIONIC PEPTIDES ALONE OR IN COMBINATION WITH ANTIBIOTICS
    Publication number: 20110150780
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Application
    Filed: November 15, 2007
    Publication date: June 23, 2011
    Applicant: Migenix Inc.
    Inventors: Timothy J. Krieger, Robert Taylor, Douglas Erfle, Janet R. Fraser, Michael H.P. West, Patricia J. McNichol
  • COMPOSITIONS AND METHODS FOR TREATING INFECTIONS USING ANALOGUES OF INDOLICIDIN
    Publication number: 20080242614
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 2, 2008
    Applicant: Migenix Inc.
    Inventors: Janet R. Fraser, Michael H. P. West, Timothy J. Krieger, Robert Taylor, Douglas Erfle
  • Compositions and methods for treating infections using analogues of indolicidin
    Patent number: 7390787
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: June 24, 2008
    Assignee: Migenix Inc.
    Inventors: Janet R. Fraser, Michael H. P. West, Timothy J. Krieger, Robert Taylor, Douglas Erfle
  • Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
    Patent number: 7309759
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: December 18, 2007
    Assignee: Migenix Inc.
    Inventors: Timothy J Krieger, Robert Taylor, Douglas Erfle, Janet R Fraser, Michael H P West, Patricia J McNicol
  • Antimicrobial cationic peptides and formulations thereof
    Patent number: 6835536
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: December 28, 2004
    Assignee: Micrologix Biotech Inc.
    Inventors: Timothy J. Krieger, Patricia J. McNicol
  • Compositions and methods for treating infections using analogues of indolicidin
    Publication number: 20040009910
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Application
    Filed: January 24, 2003
    Publication date: January 15, 2004
    Applicant: MICROLOGIX BIOTECH INC.
    Inventors: Janet R. Fraser, Michael H. P. West, Timothy J. Krieger, Robert Taylor, Douglas Erfle
  • Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
    Publication number: 20030232750
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Application
    Filed: October 18, 2002
    Publication date: December 18, 2003
    Applicant: Micrologix Biotech Inc.
    Inventors: Timothy J. Krieger, Robert Taylor, Douglas Erfle, Janet R. Fraser, Michael H.P. West, Patricia J. MicNicol
  • Antimicrobial cationic peptides and formulations thereof
    Publication number: 20030171281
    Abstract: Compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides are provided. The antimicrobial cationic peptide formulations may be used, for example, in the treatment of microorganism-caused infections, which infections may be systemic, such as a septicemia, or may be localized, such as in acne or an implanted or indwelling medical device.
    Type: Application
    Filed: August 20, 2002
    Publication date: September 11, 2003
    Applicant: MICROLOGIX BIOTECH INC.
    Inventors: Timothy J. Krieger, Patricia J. McNicol, Janet R. Fraser
  • Compositions and methods for treating infections using analogues of indolicidin
    Patent number: 6538106
    Abstract: Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: March 25, 2003
    Assignee: Micrologix Biotech, Inc.
    Inventors: Janet R. Fraser, Michael H. P. West, Timothy J. Krieger, Robert Taylor, Douglas Erfle