Abstract: Reagents which regulate human GPCR-like protein and reagents which bind to human GPCR-like protein gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, diabetes and hematological disorders.

Abstract: Reagents that regulate human MRP5-like protein and reagents which bind to human MRP5-like protein gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cardiovascular disorders, cancer, and CNS disorders.

Abstract: Reagents that regulate human cyclophilin-like protein and reagents which bind to human cyclophilin-like protein gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer.

Abstract: Reagents which regulate human L-asparaginase-like enzyme and reagents which bind to human L-asparaginase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and CNS disorders.

Abstract: Reagents which regulate human pyroglutamyl peptidase-like enzyme and reagents which bind to human pyroglutamyl peptidase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, brain and spinal cord trauma, stroke, and neurodegenerative disorders, such as amyotropic lateral sclerosis and spinocerebellar degeneration.

Abstract: Reagents which regulate human PGC-1-like protein and reagents which bind to human PGC-1-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, obesity, cardiovascular disorders, diabetes, and COPD.

Abstract: A streaming media presentation system is described. The system employs a fast method to detect a plurality of aspects about the operating environment, including bandwidth, and selects a media presentation optimized to afford the best user experience based on a plurality of streaming characteristics. The detection method is a staged method, which improves speed. In response to detected capabilities (e.g., bandwidth), the system selects an optimal stream with particular quality characteristics suited to the detected capabilities, including such features as frame rate, sharpness and frame size. The system is adaptable to existing systems that provide multiple versions of streaming presentations, whether currently automated or dependent upon user selection.

Abstract: A dehumidification system for dehumidifying a conditioned space. The system is comprised of a motionless desiccant block for dehumidifying air within the conditioned space. The system is configured to operate in one of two modes. In a first dehumidifying mode the system draws air from the conditioned space, dehumidifies the air, and returns the air to the conditioned space. In a second regeneration mode the system draws air from outside the conditioned space, heats the air, passes the heated air through the desiccant to dry the desiccant, and expels the air back outside the conditioned space. The system is configured with pivoting dampers to select air source and air destination for the two modes of the system. The system includes blowers in order to motivate the flow of air and a regenerative heater for use during regeneration mode. By utilizing a motionless desiccant block the system avoids the expense and maintenance of desiccant wheels and wheel motors.

Abstract: A ventilation and dehumidification system for ventilating fresh air to a conditioned space. The system is comprised of a unitary heat transfer desiccant wheel for dehumidifying incoming air by exchanging moisture from an inflow current of air with an outflow current of air. The unitary heat recovery wheel is able to transfer heat between the two air currents when the wheel is spun at a faster speed. The unitary heat transfer desiccant wheel is both regenerated and defrosted by a regenerative heater which is placed to heat the outflow current of air before the outflow current passes through the unitary heat transfer desiccant wheel. The unitary heat transfer desiccant wheel is spun at a slow speed to accomplish more dehumidification, and at a fast speed to accomplish more heat recovery. The system includes at least two blowers in order to motivate the inflow and outflow currents of air.

Abstract: A ventilation system for ventilating fresh air to a conditioned space, the system capable of supplying substantially more air to the space than is removed by the system in order to prevent depressurization inside the space. Passing through the unit housing is an inflow chamber, an outflow chamber, and a make-up air duct. Two blowers, an intake blower and an exhaust blower, are placed within the inflow chamber and the outflow chamber in order to motivate inflow and outflow currents of air. A damper acts to open and close the make-up air duct. When the damper is in an open position and the intake blower operates at a higher speed than the exhaust blower the system increases the air pressure within the conditioned space. A heat transfer wheel is disposed within both the inflow chamber and the outflow chamber to exchange heat between the two currents of air. A pre-heater is placed in the make-up air duct to be used in cold weather conditions to heat the air which bypasses the heat recovery wheel.

Abstract: A housing for electrical equipment has first and second halves. An electrical connecting plug between the housing halves is arranged to require halves of the plug to be separated before the housing halves can be separated.

Abstract: A control cable quick release device for use with cable-actuated brake arms that permits disengagement of the control cable from the brake arm without braking the seal between the quick release device and the deformable bellows thereby preventing premature corrosion of the control cable and permitting quick and easy removal of the bicycle wheel.

Abstract: A gage mechanism for a blood pressure measuring device or other similar apparatus includes a supported shaft member having one end in contact with an inflatable bellows. A pointer is attached at an opposite end of the shaft and a helically wound spring is attached to the shaft and a supporting structure. As the bellows inflates, the shaft is axially displaced and causes rotation due to the constraint of the helical ribbon spring, causing a corresponding angular deflection of the attached pointer relative to an indicating scale. The mechanism includes a first adjustment member for allowing the pointer to be preset to a zero or calibrated position, and a second adjustment mechanism that controls the amount of angular rotation of the shaft and pointer for a displacement of the bellows.

Abstract: A gage mechanism for a blood pressure measuring device or other similar apparatus includes a supported shaft member having one end in contact with an inflatable bellows. A pointer is attached at an opposite end of the shaft and a helically wound spring is attached to the shaft and a supporting structure. As the bellows inflates, the shaft is axially displaced and causes rotation due to the constraint of the helical ribbon spring, causing a corresponding angular deflection of the attached pointer relative to an indicating scale. The mechanism includes a first adjustment member for allowing the pointer to be preset to a zero or calibrated position, and a second adjustment mechanism that controls the amount of angular rotation of the shaft and pointer for a displacement of the bellows.

Abstract: A nozzle assembly for the water distribution tray of a humidifier has at least one arm which cooperates with a feature such as a slot on a tray wall, to hold the nozzle assembly in a desired position above a water distribution area of the tray. In a preferred embodiment, the nozzle assembly has two pairs of arms for mounting the nozzle assembly to the tray. Each pair of arms together form a wishbone shape. The arm ends of each pair can be deflected toward each other to permit the ends to enter a slot on the tray wall. When the arm ends are released within the slot, they latch with the slot to hold the nozzle assembly in the desired position.

Abstract: A gage mechanism for a blood pressure measuring device or other similar apparatus includes a supported shaft member having one end in contact with an inflatable bellows. A pointer is attached at an opposite end of the shaft and a helically wound spring is attached to the shaft and a supporting structure. As the bellows inflates, the shaft is axially displaced and causes rotation due to the constraint of the helical ribbon spring, causing a corresponding angular deflection of the attached pointer relative to an indicating scale. The mechanism includes a first adjustment member for allowing the pointer to be preset to a zero or calibrated position, and a second adjustment mechanism that controls the amount of angular rotation of the shaft and pointer for a displacement of the bellows.

Abstract: An in-duct humidifier has a permeable rectangular pad to be placed in a heated air stream. Water dripping onto the top of the pad is evaporated by the air stream which is passing through the pad to thereby increase its humidity. The pad is held in a frame and the frame is mounted in the humidifier's housing. The frame holds the pad by an arrangement of sloped surfaces and narrow projections to minimize the area of the frame in direct contact with the pad. By minimizing the contact area between the pad and the frame, the amount of water flowing onto the frame and evaporating from the frame is minimized, thereby reducing the rate and amount of minerals dissolved in the water which are deposited on the frame surfaces.

Abstract: A bicycle brake lever assembly attachable to a handlebar, comprising a lever pivotally attached to a brake housing, the housing having a substantially continuous hoop of material across the top and sides of the housing maximizing the flexural and torsional stiffness of the braking lever assembly. Impact loads from collisions With natural objects are transmitted from the brake lever through the housing to the handlebar, the housing being significantly more rigid to sustain transverse loading delivered by the lever. The housing providing a cable insertion slot on a shielded surface projecting substantially onto a plane substantially orthogonal to the bicycle handlebar.

Abstract: An in-duct humidifier has an evaporative pad onto the top of which water is dripped. Air passing through the pad evaporates the water to thereby increase the air's humidity. An improved tray for dripping the water onto the top of the pad has a sloped floor in which are a number of holes. A nozzle assembly which is mounted directly on the top of the tray and an improved arrangement of walls on the tray floor assists in delivering equal amounts of water to all of the holes, resulting in even distribution of water throughout the pad and more efficient operation of the humidifier.