Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. These assays may be performed for a variety of purposes, including but not limited to screening of drug candidate compounds, life sciences research, and clinical and molecular diagnostics. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.

Abstract: The invention provides N-pyrazinyl-thienylsulphonamides of formula (I) for use in the treatment of chemokine mediated diseases.

Abstract: Systems and methods for selectively changing the current threshold of current limiting circuitry are provided. The current limit threshold of current limiting circuitry may be selectively changed based on a detected power source using a resistive network. The current limiting threshold may be selected by changing a resistance value of a resistive network electrically coupled to an input on the current limiting circuitry (e.g., battery controller) for programming the current limiting threshold. The resistance value received by the currently limiting circuitry at this input may set the current threshold and thus the maximum magnitude of current that may be provided to charge a battery or other energy storage device located in the electronic device (e.g., a mobile phone).

Abstract: A single prong, multiple signal conducting plug and plug detection circuitry is provided. The plug may be electrically coupled to a stereo headset including a microphone. The plug may include four signal conducting regions arranged in a predetermined order along the length of the prong. Detection circuitry may be operative to determine whether a microphone type of plug (e.g., a four region plug including a microphone region and two audio regions, or a three region plug including microphone region and only one audio region) or a non-microphone type of plug (e.g., stereo plug) is inserted into the jack of an electronic device (e.g., mobile phone). Detection circuitry may also detect user activated functions performed in response to user activation of one or more switches included with the headset. For example, the headset may include a single switch for performing a function with respect to a microphone (e.g., end-call function).

Abstract: A content delivery network (CDN) service provider extends a content delivery network to gather information on atomically identifiable web clients (called “user agents”) as such computer-implemented entities interact with the CDN across different domains being managed by the CDN service provider. In one embodiment, a set of machines, processes, programs, and data comprise a data system. The data system tracks user agents, preferably via cookies, although one or more passive techniques may be used. A user agent may be a cookie-able device having a cookie store. As the user agent navigates across sites, a CDN-specific unique identifier used by the system to correlate user agents is generated. Preferably, the unique identifier is stored as an encrypted cookie. The unique identifier represents one user agent (and, thus, one cookie-able device's store).

Abstract: A content delivery network (CDN) service provider extends a content delivery network to gather information on atomically identifiable web clients (called “user agents”) as such computer-implemented entities interact with the CDN across different domains being managed by the CDN service provider. In one embodiment, a set of machines, processes, programs, and data comprise a data system. The data system tracks user agents, preferably via cookies, although one or more passive techniques may be used. A user agent may be a cookie-able device having a cookie store. As the user agent navigates across sites, a CDN-specific unique identifier used by the system to correlate user agents is generated. Preferably, the unique identifier is stored as an encrypted cookie. The unique identifier represents one user agent (and, thus, one cookie-able device's store).

Abstract: A content delivery network (CDN) service provider extends a content delivery network to gather information on atomically identifiable web clients (called “user agents”) as such computer-implemented entities interact with the CDN across different domains being managed by the CDN service provider. In one embodiment, a set of machines, processes, programs, and data comprise a data system. The data system tracks user agents, preferably via cookies, although one or more passive techniques may be used. A user agent may be a cookie-able device having a cookie store. As the user agent navigates across sites, a CDN-specific unique identifier used by the system to correlate user agents is generated. Preferably, the unique identifier is stored as an encrypted cookie. The unique identifier represents one user agent (and, thus, one cookie-able device's store).

Abstract: A content delivery network (CDN) service provider extends a content delivery network to gather information on atomically identifiable web clients (called “user agents”) as such computer-implemented entities interact with the CDN across different domains being managed by the CDN service provider. In one embodiment, a set of machines, processes, programs, and data comprise a data system. The data system tracks user agents, preferably via cookies, although one or more passive techniques may be used. A user agent may be a cookie-able device having a cookie store. As the user agent navigates across sites, a CDN-specific unique identifier used by the system to correlate user agents is generated. Preferably, the unique identifier is stored as an encrypted cookie. The unique identifier represents one user agent (and, thus, one cookie-able device's store).

Abstract: A turbine wheel on a horizontal axis is constructed on a network of cables radially and circumferentially connected and supported centrifugally by a ring with a friction-reduction method to permit turning within said ring. The ring structure is composed of buoyancy-controlled modules to allow construction of extremely large systems deployable in ocean depths. Electrical equipment can be variously attached for generation of power.

Abstract: A portable media playing device incorporating a menu structure. The device includes a display mechanism, a navigation database, including a navigation record with a navigation description, and an action database, including an action record with an action description. The action database is customizable. A display driver displays the navigation description. When the navigation description is selected, the display driver displays the action description. When the action description is selected, a digital synchronization system generates an extra action request (EAR) record that includes an action identifier and action data for storage in an EAR database. When the device is synchronized with a computer, a synchronization manager accesses the EAR database and updates the action database with any new action records.

Abstract: An apparatus for performing a biological or biochemical reaction that, in certain embodiments, has the ability to generate flow in a reaction site container by applying a force to a liquid medium that is outside of the reaction site container. In some embodiments, a flow generating component such as a gas bubble moves within a container and forces an agitating fluid to move through a reaction site container. In some embodiments, the movement of the agitating fluid applies shear stress to cells that are maintained within the reaction site container.

Abstract: Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical composition.

Abstract: A vest is configured to serve as a portable lockout station, whereby maintenance workers may conveniently carry safety lockout padlocks (and their keys) and safety lockout tags from one maintenance location to another to allow them to impose a safety lockout on machinery when working on the machinery. The vest is preferably brightly colored and provided with reflective stripes so that it is readily visible to others around the maintenance location, and it includes pockets which are specially configured to complementarily fit safety lockout padlocks and tags for easy storage and access. The pockets are also formed of material which is at least partially transparent, such as mesh, and are placed on a location on the vest which is readily visible to the wearer such that the wearer can readily note when a safety lockout padlock is absent (e.g., when one has been forgotten at a prior maintenance location).

Abstract: A mandrel assembly has a mandrel, a biasing member, and a outer member. The biasing member biasly maintains the outer member in a first position, which corresponds to a contoured portion of the mandrel, when the outer member is either on the access or the blind side of a workpiece. The biasing member is compressible to allow the outer member to move into a second position as the outer member is moved through an opening in the workpiece. In the first position, the outer member includes a maximum outer circumference that is larger than the opening of the structural workpiece. In the second position, the outer member includes a maximum outer circumference that fits within the opening of the structural workpiece.

Abstract: Methods for forming chemical and/or biological products in reactors, and/or analyzing chemical and/or biological interactions in reactors are provided. The methods relate, more specifically, to forming such products and/or carrying out such analyses in small volume reactors with control over overall fluid volume in the reactors. The methods can be used to mimic processes in large scale reactors and/or to obtain reaction or interaction information relevant to large scale reactors (e.g., to adjust/optimize large-scale reactor processes). Advantageously, the methods can allow parameters of small scale reactors to be correlated with those of large scale reactors, where desired.

Abstract: A portable media playing device incorporating a database-driven menu structure that comprises a display mechanism, navigation database, including a navigation record with a navigation description, an action database, including an action record with an action description, wherein the action database is customizable in accordance with a field of the navigation record. A display driver displays the navigation description. When the navigation description is selected, the display driver displays the action description. When the action description is selected, a digital synchronization system generates an extra action request (EAR) record that includes an action identifier and action data for storage in an EAR database. When the device is synchronized with a computer, a synchronization manager accesses the EAR database and updates the action database with any new action records.

Abstract: The present invention is a three dimensional insect trap, for capturing, numerating, determining population levels and controlling insects by physical trapping, mass trapping and mating disruption. The trap is comprised of a bottom piece, a top piece, a device for hanging pheromones, kairomones or other attractants and an area for either a replaceable component used for mating disruption via auto-dissemination, an adhesive-coated grid-marked floor or a capture reservoir for holding soapy water or oil. The trap can be hung within the insect environment by a device on the top piece or by attachment to a vertical stake or pole by use of support brackets.

Abstract: This disclosure relates to a pre-assembled fastener assembly having a retainer, a nut member, and a cold expansion mandrel that is forcibly removable after the assembly is installed into an opening of a structural workpiece. The mandrel is captured between a portion of a retainer and a portion of a nut member. The forced removal of the mandrel expands the retainer into the opening, securing the fastener assembly therein. The assembly may also include a cap coupled to the retainer to seal the opening in the structural workpiece. The nut member can be fixed or free-floating with respect to the retainer. In addition, the nut member can be threaded to receive a fastener. The mandrel is recyclable or disposable.

Abstract: A backpack is adapted to store an umbrella in a compact configuration within the backpack, and to enable to the user to selectively deploy and adjust the umbrella so as to shield the backpack wearer. The umbrella is compactly stored in a generally tubular storage compartment connected to the backpack and may be auto-deployed to a telescopically extended configuration in overhead shielding relation with the user. In an alternate embodiment, the umbrella is rotationally or positionally adjustable to provide cover from the elements, such as morning or afternoon sun, or wind driven rain.

Abstract: The present invention generally relates to chemical, biological, and/or biochemical reactor microreactors and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a reactor on a chip has a container in fluid communication with a channel, and the channel is in fluid communication with a port for connecting the container to a source of fluid to be introduced into the container. The container can be very small, for example, with a volume of less than about 2 milliliters, and the fluid channel can have a channel volume of less than 1.5 percent of the container volume. According to another aspect, the combined volume of the port volume and the channel volume can be less than about 10 percent of the container volume. Such a configuration may increase the percentage of added fluid that reaches the container.