Abstract: Systems and methods are provided for sharing maps in a collaborative environment using classification-based access control. The generation of and dissemination of maps and/or data within such maps can be governed by classification-based access control, where a user's classification level can determine whether or not maps and/or data within those maps can be seen. In scenarios whether a plurality of users wishes to collaborate on the same map, the systems and methods provided herein generate multiple versions or views of the same map in accordance with different classification levels. In this way, users with different classification levels can nevertheless see the same map and engage in collaborations regarding the same map, while maintaining control of sensitive data.

Abstract: The disclosure is directed to support devices and methods of making and using the same. A support device of the disclosure may be provided to hold one or more items, such as an electronic device. The support device can include (a) a base assembly; (b) a stand assembly pivotally attached to the base by a hinge, and the stand assembly including a first rotation assembly; and (c) an engagement assembly that includes a second rotation assembly, and the second rotation assembly engaged with the first rotation assembly such that the engagement assembly is rotatably attached to and supported on the stand assembly; and (d) a removable platform assembly that is slidably and removably supported on the engagement assembly, and the removable platform assembly including an attachment element that is configured to attach to a user device.

Abstract: Systems and methods are provided for sharing maps in a collaborative environment using classification-based access control. The generation of and dissemination of maps and/or data within such maps can be governed by classification-based access control, where a user's classification level can determine whether or not maps and/or data within those maps can be seen. In scenarios whether a plurality of users wishes to collaborate on the same map, the systems and methods provided herein generate multiple versions or views of the same map in accordance with different classification levels. In this way, users with different classification levels can nevertheless see the same map and engage in collaborations regarding the same map, while maintaining control of sensitive data.

Abstract: Systems, methods, and non-transitory computer readable media are provided for using linked documents. A system may receive, from a computing device, a request for a document. Content of the document may be defined based on state information and stateless information. A system may determine a local replica of the document in a local database. The local replica of the document may be linked to a primary replica of the document. The local replica of the document may include a snapshot of the primary replica of the document. The primary replica of the document may be stored in a remote database which may be accessible through a remote server. The system may subscribe to the primary replica of the document through the remote server, and may provide access to the document to the computing device based at least in part on the subscription to the primary replica of the document.

Abstract: The present disclosure provides methods and systems for nucleic acid sequencing. Such systems and methods may use a single flow cell to perform unbiased and/or biased sequencing to generate libraries of nucleic acid molecules. An aspect of the present disclosure provides a method for increasing complexity of a sample for sequencing, the method comprising: providing a first nucleic acid sample having a first degree of complexity that differs from a desired degree of complexity; providing a second nucleic acid sample having a second degree of complexity that differs from the first degree of complexity and that differs from the desired degree of complexity; pooling at least a portion of the first nucleic acid sample and at least a portion of the second nucleic acid sample, thereby generating a pooled nucleic acid sample having the desired degree of complexity; and sequencing at least a portion of the pooled nucleic acid sample.

Abstract: Presented are methods and compositions for spatial detection and analysis of nucleic acids in a tissue sample. The methods can enable the characterization of transcriptomes and/or genomic variations in tissues while preserving spatial information about the tissue.

Abstract: Systems and methods are provided for master-to-master OT-based artifact peering. A “master-to-master” architecture for artifacts is implemented in a network comprising a plurality of nodes and clients, where no node is designated a “master” or “primary” for a given artifact. A first node receives a subset of remote proposed operations from a second node and determines if a conflict exists between the received subset of remote proposed operations and at least one of a plurality of locally-proposed operations. The first node resolves the conflict based on a total-ordering agreed upon between the first node and the second node. The first node transforms at least one operation, either received or locally-proposed, based on the resolved conflict. The first node than updates a local log to include the transformed operation.

Abstract: Systems and methods are provided for adaptive data replication. A first data object is stored. One or more first network characteristics of a communication network are detected. A first replication mode is triggered (e.g., a single-master replication mode) based on the one or more first network characteristics of the communication network. The single-master replication may be configured to facilitate real-time synchronizations (e.g., for critical updates). One or more second network characteristics of the communication network are detected. A second replication mode (e.g., a multi-master replication mode) is triggered based on the one or more second network characteristics. The second replication may be configured to facilitate a delayed synchronization (e.g., for non-critical updates) of the first data object and the second data object using the second update file.

Abstract: Systems, methods, and non-transitory computer readable media are provided for using linked documents. A system may receive, from a computing device, a request for a document. Content of the document may be defined based on state information and stateless information. A system may determine a local replica of the document in a local database. The local replica of the document may be linked to a primary replica of the document. The local replica of the document may include a snapshot of the primary replica of the document. The primary replica of the document may be stored in a remote database which may be accessible through a remote server. The system may subscribe to the primary replica of the document through the remote server, and may provide access to the document to the computing device based at least in part on the subscription to the primary replica of the document.

Abstract: Systems and methods are provided for adaptive data replication. A first data object is stored. One or more first network characteristics of a communication network are detected. A first replication mode is triggered (e.g., a single-master replication mode) based on the one or more first network characteristics of the communication network. The single-master replication may be configured to facilitate real-time synchronizations (e.g., for critical updates). One or more second network characteristics of the communication network are detected. A second replication mode (e.g., a multi-master replication mode) is triggered based on the one or more second network characteristics. The second replication may be configured to facilitate a delayed synchronization (e.g., for non-critical updates) of the first data object and the second data object using the second update file.

Abstract: Presented are methods and compositions for spatial detection and analysis of nucleic acids in a tissue sample. The methods can enable the characterization of transcriptomes and/or genomic variations in tissues while preserving spatial information about the tissue.

Abstract: A system may determine one or more data sources which the system is configured to access. The system may provide a set of application programming interfaces (APIs) for interacting with data stored in one or more data sources. The APIs may be accessible to one or more web applications which the system is configured to serve. The system may determine that a web application has requested an operation for interacting with the data through one or more APIs in the set of APIs. The system may determine one or more responses based at least in part on the operation requested by the web application. The system may provide the response(s) to the web application.

Abstract: A jarring device includes a housing, a mandrel received within the housing, and a pressure chamber defined between the housing and the mandrel and filled with a hydraulic fluid. A hydraulic lock piston is arranged about the mandrel and radially interposes the housing and the mandrel. The hydraulic lock piston includes a pressure piston having a first end exposed to the pressure chamber, a second end, and first and second fluid flowpaths defined in the pressure piston and extending axially between the first and second ends. When the mandrel moves in a first direction relative to the housing, the hydraulic fluid is metered through the first fluid flowpath and the second fluid flowpath is occluded. When the mandrel moves in a second direction relative to the housing and opposite the first direction, the hydraulic fluid is metered through the second fluid flowpath and the first fluid flowpath is occluded.

Abstract: A system may determine one or more data sources which the system is configured to access. The system may provide a set of application programming interfaces (APIs) for interacting with data stored in one or more data sources. The APIs may be accessible to one or more web applications which the system is configured to serve. The system may determine that a web application has requested an operation for interacting with the data through one or more APIs in the set of APIs. The system may determine one or more responses based at least in part on the operation requested by the web application. The system may provide the response(s) to the web application.

Abstract: Systems and methods are provided for sharing maps in a collaborative environment using classification-based access control. The generation of and dissemination of maps and/or data within such maps can be governed by classification-based access control, where a user's classification level can determine whether or not maps and/or data within those maps can be seen. In scenarios whether a plurality of users wishes to collaborate on the same map, the systems and methods provided herein generate multiple versions or views of the same map in accordance with different classification levels. In this way, users with different classification levels can nevertheless see the same map and engage in collaborations regarding the same map, while maintaining control of sensitive data.

Abstract: Example embodiments relate to a notification system. The notification system accesses a set of components of a first data object, a user having registered to monitor the first data object for modifications. The notification system compares the set of components of the first data object to a previous set of components of the first data object and determines, based on the comparison, that the set of components of the first data object includes at least one modification from the previous set of components of the first data object. In response to determining that the set of components of the first data object includes at least one modification from the previous set of components of the first data object, the notification system notifies the user of the at least one modification to the first data object.

Abstract: Systems and methods are provided for sharing maps in a collaborative environment using classification-based access control. The generation of and dissemination of maps and/or data within such maps can be governed by classification-based access control, where a user's classification level can determine whether or not maps and/or data within those maps can be seen. In scenarios whether a plurality of users wishes to collaborate on the same map, the systems and methods provided herein generate multiple versions or views of the same map in accordance with different classification levels. In this way, users with different classification levels can nevertheless see the same map and engage in collaborations regarding the same map, while maintaining control of sensitive data.

Abstract: Systems, methods, and non-transitory computer readable media are provided for using linked documents. A system may receive, from a computing device, a request for a document. Content of the document may be defined based on state information and stateless information. A system may determine a local replica of the document in a local database. The local replica of the document may be linked to a primary replica of the document. The local replica of the document may include a snapshot of the primary replica of the document. The primary replica of the document may be stored in a remote database which may be accessible through a remote server. The system may subscribe to the primary replica of the document through the remote server, and may provide access to the document to the computing device based at least in part on the subscription to the primary replica of the document.

Abstract: A jarring device includes a housing, a mandrel received within the housing, and a pressure chamber defined between the housing and the mandrel and filled with a hydraulic fluid. A hydraulic lock piston is arranged about the mandrel and radially interposes the housing and the mandrel. The hydraulic lock piston includes a pressure piston having a first end exposed to the pressure chamber, a second end, and first and second fluid flowpaths defined in the pressure piston and extending axially between the first and second ends. When the mandrel moves in a first direction relative to the housing, the hydraulic fluid is metered through the first fluid flowpath and the second fluid flowpath is occluded. When the mandrel moves in a second direction relative to the housing and opposite the first direction, the hydraulic fluid is metered through the second fluid flowpath and the first fluid flowpath is occluded.