Patents by Inventor Tina K. Van Dyk

Tina K. Van Dyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular arrays for the identification of altered gene expression
    Patent number: 6716582
    Abstract: The present invention relates to the generation and use of a cellular array or a cellular array in combination with other genome-registered arrays (an array of arrays) for the determination of gene function and/or perturbation mode of action. Each cellular array consists of a number of microbial strains. Each strain comprises one reporter gene fusion made up of a gene or gene fragment operably linked to a reporter gene. Each gene or gene fragment has been “registered” or mapped to a specific location in the genome of the organism. The genome-registered collection of the invention may be used to determine alterations in gene expression under a variety of conditions. Such collections are amenable to rapid assay and may be used to confirm, correct or augment data generated from DNA micro array technology.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: April 6, 2004
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Gregory E. Gonye, Michael K. Hanafey, Robert A. LaRossa, J. Antoni Rafalski, Tina K. Van Dyk
  • Cellular arrays for the identification of altered gene expression
    Publication number: 20040009485
    Abstract: The present invention relates to the generation and use of a cellular array or a cellular array in combination with other genome-registered arrays (an array of arrays) for the determination of gene function and/or perturbation mode of action. Each cellular array consists of a number of microbial strains. Each strain comprises one reporter gene fusion made up of a gene or gene fragment operably linked to a reporter gene. Each gene or gene fragment has been “registered” or mapped to a specific location in the genome of the organism. The genome-registered collection of the invention may be used to determine alterations in gene expression under a variety of conditions. Such collections are amenable to rapid assay and may be used to confirm, correct or augment data generated from DNA micro array technology.
    Type: Application
    Filed: August 29, 2002
    Publication date: January 15, 2004
    Inventors: Gregory E. Gonye, Robert A. Larossa, Tina K. Van Dyk, Antoni J. Rafalski, Michael K. Hanafey
  • Cellular arrays for the identification of altered gene expression
    Publication number: 20030219736
    Abstract: The present invention relates to the generation and use of a cellular array or a cellular array in combination with other genome-registered arrays (an array of arrays) for the determination of gene function and/or perturbation mode of action. Each cellular array consists of a number of microbial strains. Each strain comprises one reporter gene fusion made up of a gene or gene fragment operably linked to a reporter gene. Each gene or gene fragment has been “registered” or mapped to a specific location in the genome of the organism. The genome-registered collection of the invention may be used to determine alterations in gene expression under a variety of conditions.
    Type: Application
    Filed: April 11, 2001
    Publication date: November 27, 2003
    Inventors: Gregory E. Gonye, Michael K. Hanafey, Robert A. Larossa, J. Antoni Rafalski, Tina K. Van Dyk