Patents by Inventor Tina LI

Tina LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240151713
    Abstract: Provided are methods and articles of manufacture for use with cell therapy for the treatment of diseases or conditions, e.g., cancer, including for predicting and treating a toxicity. In some embodiments, the toxicity is a neurotoxicity or cytokine release syndrome (CRS), such as a severe neurotoxicity or a severe CRS. The methods generally involve detecting a marker by assaying a biological sample from a subject that is a candidate for treatment, optionally with a cell therapy, to determine if the subject is at risk for developing the toxicity, such as neurotoxicity or CRS or severe neurotoxicity or severe CRS. In some embodiments, the methods and articles of manufacture further includes a regent for assaying the biological sample and instructions for determining the percentage or number of cells positive for the marker in the biological sample.
    Type: Application
    Filed: July 5, 2023
    Publication date: May 9, 2024
    Applicant: Juno Therapeutics, Inc.
    Inventors: Nathan YEE, Chris Glen RAMSBORG, Tina ALBERTSON, Ryan LARSON, He LI
  • Publication number: 20240115612
    Abstract: Provided are adoptive cell therapy methods involving the administration of doses of cells for treating disease and conditions, including certain B cell malignancies. The cells generally express recombinant receptors such as chimeric antigen receptors (CARs). In some embodiments, the methods are for treating subjects with non-Hodgkin lymphoma (NHL). In some embodiments, the methods are for treating subjects with relapsed or refractory NHL. Also provided are articles of manufacture and prophylactic treatments in connection with adoptive therapy methods.
    Type: Application
    Filed: November 15, 2023
    Publication date: April 11, 2024
    Applicant: Juno Therapeutics, Inc.
    Inventors: Tina ALBERTSON, Brian CHRISTIN, Jacob Randolph GARCIA, Christopher Glen RAMSBORG, Claire L. SUTHERLAND, Clinton WEBER, Rachel K. YOST, Mark J. GILBERT, He LI
  • Patent number: 11944647
    Abstract: Provided are adoptive cell therapy methods involving the administration of doses of cells for treating disease and conditions, including certain B cell malignancies. The cells generally express recombinant receptors such as chimeric antigen receptors (CARs). In some embodiments, the methods are for treating subjects with non-Hodgkin lymphoma (NHL). In some embodiments, the methods are for treating subjects with relapsed or refractory NHL. Also provided are articles of manufacture and prophylactic treatments in connection with adoptive therapy methods.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: April 2, 2024
    Assignee: Juno Therapeutics, Inc.
    Inventors: Tina Albertson, Brian Christin, Jacob Randolph Garcia, Christopher Glen Ramsborg, Claire L. Sutherland, Clinton Weber, Rachel K. Yost, Mark J. Gilbert, He Li
  • Patent number: 10486619
    Abstract: A connection assembly in a vehicle comprises a bracket including a sliding groove; and a connector including a base plate configured to be received in the sliding groove of the bracket. The base plate or an inner wall of the sliding groove has a raised portion and a through hole on the raised portion. At a locked position, the base plate is at least partially received in the sliding groove and contacts the inner wall of the sliding groove under a pressure via the raised portion.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: November 26, 2019
    Assignee: Ford Global Technologies LLC
    Inventors: Tina Li, Yong Gao, Hallie Ge
  • Patent number: 10344186
    Abstract: The invention provides a chemical-mechanical polishing composition comprising (a) wet-process ceria abrasive, (b) a surfactant comprising an amine-containing anchor group and ethylene oxide-propylene oxide stabilizing group, wherein the surfactant has a molecular weight of from about 1000 Daltons to about 5000 Daltons, (c) an aromatic carboxylic acid or heteroaromatic carboxylic acid, and (d) water, wherein the polishing composition has a pH of about 3 to about 6. The invention further provides a method of chemically mechanically polishing a substrate with the inventive chemical-mechanical polishing composition. Typically, the substrates contain silicon oxide.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: July 9, 2019
    Assignee: Cabot Microelectronics Corporation
    Inventors: Alexander W. Hains, Tina Li
  • Patent number: 10308195
    Abstract: A fastener assembly for an interior trim part in a vehicle is provided. The fastener assembly includes a fixed element and a movable element. The fixed element includes a base panel with a through hole and a plurality of engaging parts extending from a surface of the base panel, and the engaging parts are flexible and deformable towards or away from a central axis of the through hole. The movable element includes a flange and an engaging shaft extending from a surface of the flange, and the engaging shaft passes through the through hole of the fixed element to be engaged with the engaging parts at a fixed position.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: June 4, 2019
    Assignee: Ford Global Technologies LLC
    Inventors: Tina Li, Yong Gao, Lillian Long, Yalin Zhang
  • Patent number: 10301508
    Abstract: The invention provides a chemical-mechanical polishing composition comprising (a) wet-process ceria, (b) a water-soluble cationic polymer or copolymer, (c) an aromatic carboxylic acid or heteroaromatic carboxylic acid, and (d) water, wherein the polishing composition has a pH of about 3 to about 6. The invention further provides a method of chemically-mechanically polishing a substrate with the inventive chemical-mechanical polishing composition. Typically, the substrate contains silicon oxide.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: May 28, 2019
    Assignee: Cabot Microelectronics Corporation
    Inventors: Viet Lam, Tina Li
  • Patent number: 10173636
    Abstract: The seatbelt buckle assembly comprises a buckle; a buckle supporting member connected to the buckle and including thereupon a first aperture and an opposing second aperture spaced apart along a width direction together to receive a fastener for assembling the buckle supporting member to the structural frame; and a spring to contact the buckle supporting member and the structural frame.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: January 8, 2019
    Assignee: Ford Global Technologies, LLC
    Inventors: Tony Wang, Angel Ding, Fiona Yang, Tina Li
  • Publication number: 20180370456
    Abstract: A connection assembly in a vehicle comprises a bracket including a sliding groove; and a connector including a base plate configured to be received in the sliding groove of the bracket. The base plate or an inner wall of the sliding groove has a raised portion and a through hole on the raised portion. At a locked position, the base plate is at least partially received in the sliding groove and contacts the inner wall of the sliding groove under a pressure via the raised portion.
    Type: Application
    Filed: June 26, 2017
    Publication date: December 27, 2018
    Inventors: Tina Li, Yong Gao, Hallie Ge, Tony Wang
  • Patent number: 10121616
    Abstract: A window switch assembly of a vehicle comprises a base; a rail on the base; and a control member partially received in the rail and slidable in the rail. The rail includes a first rail body extending at a traverse direction, a first end portion and a second end portion communicated with the first rail body. The first end portion includes a first switch and a second switch opposite each other in a longitudinal direction, and the second end portion includes a third switch and a fourth switch opposite each other in the longitudinal direction. The control member selectively contacts the first switch and the second switch to control a first window, and selectively contacts the third switch and the fourth switch to control a second window.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: November 6, 2018
    Assignee: Ford Global Technologies, LLC
    Inventors: Jason Zhou, Layla Mi, Tina Li, Fiona Yang
  • Publication number: 20180099624
    Abstract: A fastener assembly for an interior trim part in a vehicle is provided. The fastener assembly comprises a fixed element and a movable element. The fixed element includes a base panel with a through hole and a plurality of engaging parts extending from a surface of the base panel, and the engaging parts are flexible and deformable towards or away from a central axis of the through hole. The movable element includes a flange and an engaging shaft extending from a surface of the flange, and the engaging shaft passes through the through hole of the fixed element to be engaged with the engaging parts at a fixed position.
    Type: Application
    Filed: September 7, 2017
    Publication date: April 12, 2018
    Inventors: Tina Li, Yong Gao, Lillian Long, Yalin Zhang
  • Publication number: 20180082811
    Abstract: A window switch assembly of a vehicle comprises a base; a rail on the base; and a control member partially received in the rail and slidable in the rail. The rail includes a first rail body extending at a traverse direction, a first end portion and a second end portion communicated with the first rail body. The first end portion includes a first switch and a second switch opposite each other in a longitudinal direction, and the second end portion includes a third switch and a fourth switch opposite each other in the longitudinal direction. The control member selectively contacts the first switch and the second switch to control a first window, and selectively contacts the third switch and the fourth switch to control a second window.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 22, 2018
    Inventors: Jason Zhou, Layla Mi, Tina Li, Fiona Yang
  • Publication number: 20170369742
    Abstract: The invention provides a chemical-mechanical polishing composition comprising (a) wet-process ceria abrasive, (b) a surfactant comprising an amine-containing anchor group and ethylene oxide-propylene oxide stabilizing group, wherein the surfactant has a molecular weight of from about 1000 Daltons to about 5000 Daltons, (c) an aromatic carboxylic acid or heteroaromatic carboxylic acid, and (d) water, wherein the polishing composition has a pH of about 3 to about 6. The invention further provides a method of chemically mechanically polishing a substrate with the inventive chemical-mechanical polishing composition. Typically, the substrates contain silicon oxide.
    Type: Application
    Filed: June 21, 2017
    Publication date: December 28, 2017
    Inventors: Alexander W. HAINS, Tina LI
  • Patent number: 9796882
    Abstract: Described are compositions useful in methods for chemical-mechanical processing a surface of a substrate, especially a substrate that contains dielectric material, wherein the composition contains cyclodextrin and an alkylamine.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: October 24, 2017
    Assignee: Cabot Microelectronics Corporation
    Inventors: Alexander W. Hains, Tina Li
  • Patent number: 9771496
    Abstract: Described are chemical-mechanical polishing compositions (e.g., slurries) and methods of using the slurries for chemical-mechanical polishing (or planarizing) a surface of a substrate that contains tungsten, the compositions containing cationic surfactant and cyclodextrin.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: September 26, 2017
    Assignee: Cabot Microelectronics Corporation
    Inventors: Kevin Dockery, Helin Huang, Lin Fu, Tina Li
  • Publication number: 20170210946
    Abstract: The invention provides a chemical-mechanical polishing composition comprising (a) wet-process ceria, (b) a water-soluble cationic polymer or copolymer, (c) an aromatic carboxylic acid or heteroaromatic carboxylic acid, and (d) water, wherein the polishing composition has a pH of about 3 to about 6. The invention further provides a method of chemically-mechanically polishing a substrate with the inventive chemical-mechanical polishing composition. Typically, the substrate contains silicon oxide.
    Type: Application
    Filed: January 25, 2017
    Publication date: July 27, 2017
    Inventors: Viet LAM, Tina LI
  • Publication number: 20170183540
    Abstract: Described are compositions useful in methods for chemical-mechanical processing a surface of a substrate, especially a substrate that contains dielectric material, wherein the composition contains cyclodextrin and an alkylamine.
    Type: Application
    Filed: December 29, 2016
    Publication date: June 29, 2017
    Inventors: Alexander W. HAINS, Tina LI
  • Publication number: 20170174177
    Abstract: The seatbelt buckle assembly comprises a buckle; a buckle supporting member connected to the buckle and including thereupon a first aperture and an opposing second aperture spaced apart along a width direction together to receive a fastener for assembling the buckle supporting member to the structural frame; and a spring to contact the buckle supporting member and the structural frame.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 22, 2017
    Inventors: Tony Wang, Angel Ding, Fiona Yang, Tina Li
  • Publication number: 20170121560
    Abstract: Described are chemical-mechanical polishing compositions (e.g., slurries) and methods of using the slurries for chemical-mechanical polishing (or planarizing) a surface of a substrate that contains tungsten, the compositions containing cationic surfactant and cyclodextrin.
    Type: Application
    Filed: October 28, 2015
    Publication date: May 4, 2017
    Inventors: Kevin DOCKERY, Helin HUANG, Lin FU, Tina LI
  • Patent number: 9567491
    Abstract: A chemical-mechanical polishing composition includes colloidal silica abrasive particles having a chemical compound incorporated therein. The chemical compound may include a nitrogen-containing compound such as an aminosilane or a phosphorus-containing compound. Methods for employing such compositions include applying the composition to a semiconductor substrate to remove at least a portion of a layer.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: February 14, 2017
    Assignee: Cabot Microelectronics Corporation
    Inventors: Lin Fu, Steven Grumbine, Jeffrey Dysard, Tina Li