Patents by Inventor Ting Guo

Ting Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10323237
    Abstract: A lysozyme having improved enzymatic activity is disclosed. The amino acid sequence of the lysozyme is a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of histidine at position 166 or a corresponding position with lysine.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: June 18, 2019
    Assignee: CHENGDU BEACON BIO-TECHNOLOGY CO., LTD.
    Inventors: Chun-Chi Chen, Tao Wang, Jian-Wen Huang, Rey-Ting Guo
  • Patent number: 10316303
    Abstract: A lactone hydrolase having improved activity towards ?-zearalenol is disclosed. The lactone hydrolase has a modified amino acid sequence of SEQ ID NO: 5, wherein the modification is a substitution of valine at position 167 with histidine. A method of degrading ?-zearalenol using such lactone hydrolase is also disclosed.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: June 11, 2019
    Assignee: TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Rey-Ting Guo, Yingying Zheng, Zhongxia Xu, Chun-Chi Chen, Wei Peng, Weidong Liu, Je-Ruei Liu, Yanhe Ma
  • Publication number: 20190127716
    Abstract: A lysozyme having improved enzymatic activity is disclosed. The amino acid sequence of the lysozyme is a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of histidine at position 166 or a corresponding position with lysine.
    Type: Application
    Filed: August 21, 2018
    Publication date: May 2, 2019
    Inventors: Chun-Chi Chen, Tao Wang, Jian-Wen Huang, Rey-Ting Guo
  • Publication number: 20190119687
    Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.
    Type: Application
    Filed: October 11, 2018
    Publication date: April 25, 2019
    Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Patent number: 10233430
    Abstract: A glucose oxidase having improved thermostability is disclosed. The amino acid sequence of the glucose oxidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of glutamate at position 129 with proline, and/or a substitution of glutamine at position 243 with valine.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: March 19, 2019
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO.,LTD.
    Inventors: Ya-Shan Cheng, Tzu-Hui Wu, Cheng-Yen Lin, Hui-Lin Lai, Cheng-Bin Zheng, Ting-Yung Huang, I-Hsuan Lin, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Publication number: 20180328921
    Abstract: Provided herein are methods and materials that allow targeting and imaging of interactions between probes and targets. In some embodiments, the probes include nanoscale materials with embedded solutions that can be used to measure physical enhancement by materials under X-ray irradiation. In some embodiments, the methods of the present invention include delivering a probe material to a target that can have a delivered donor material. In some embodiments, methods of the present invention include irradiating the target and determining an optical change in the probe characteristic of a physical enhancement.
    Type: Application
    Filed: July 20, 2018
    Publication date: November 15, 2018
    Applicant: The Regents of the University of California
    Inventor: Ting Guo
  • Patent number: 10011822
    Abstract: A phytase having improved thermostability is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is one of mutations A to D. The mutation A is to substitute amino acids at positions 143 and 262 with cysteine, the mutation B is to substitute amino acids at positions 259 and 312 with cysteine, the mutation C is to substitute amino acids at positions 205 and 257 with cysteine, and the mutation D is to substitute amino acids at positions 264 and 309 with cysteine.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: July 3, 2018
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Tzu-Hui Wu, Ya-Shan Cheng, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo
  • Patent number: 9993553
    Abstract: The present disclosure relates generally to the field of nanoscale materials, and more specifically to the field of nanoscale materials for activating delivered molecules at a target location.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 12, 2018
    Assignee: The Regents of the University of California
    Inventors: Ting Guo, Zane B. Starkewolfe
  • Patent number: 9944915
    Abstract: A cellulase having improved thermostability is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is adding a cysteine in N terminal and adding a glycine and a cysteine or adding a proline and a cysteine in C terminal.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 17, 2018
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Publication number: 20180085731
    Abstract: The present disclosure relates to methods of combining chemical enhancement and physical enhancement to produce a combined synergistic total enhancement, and more specifically to methods of irradiating samples containing nanomaterials capable of producing chemical or physical enhancement to produce combined synergistic total enhancement.
    Type: Application
    Filed: November 30, 2017
    Publication date: March 29, 2018
    Applicant: The Regents of the University of California
    Inventor: Ting Guo
  • Patent number: 9835924
    Abstract: A silicon based terahertz full wave liquid crystal phase shifter is provided. The liquid crystal phase shifter has a first silicon conductive substrate, a second silicon conductive substrate, a plurality of pads, and a liquid crystal. The first and second silicon conductive substrates, instead of the quartz glass and transparent electrode, such as ITO, are used as substrates and to provide electrodes of the liquid crystal phase shifter. Thus, the effect of the liquid crystal phase modulation of the liquid crystal phase shifter in the THz range can be improved.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: December 5, 2017
    Assignee: National Sun Yat-Sen University
    Inventors: Chao-Kuei Lee, Han-Wei Zhang, Tsung-Hsien Lin, Chun-Ta Wang, Jun-Ting Guo
  • Publication number: 20170341946
    Abstract: Described are composite photonic materials that incorporate magnetic nanoparticles inside hollow or solvent-filled nano-scale or micro-scale shells and methods of making and using such composite photonic materials. When these photonic materials are present in a magnetic field, they exhibit a change in reflected, scattered, and/or transmitted light as compared to when the materials are not in the presence of the magnetic field. This results in the materials appearing to have a different color, such as when observed by the human eye or a light detecting device, such as a camera.
    Type: Application
    Filed: June 13, 2017
    Publication date: November 30, 2017
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Ting Guo
  • Patent number: 9809807
    Abstract: A cellulase having improved enzymatic activity is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 161 with Histidine.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: November 7, 2017
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Chun-Chi Chen, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9764305
    Abstract: A principle is established to show that nanoscale energy deposition in water by X-rays can be greatly enhanced via the geometry of nanostructures. The calculated results show that enhancement over background water can reach over 60 times for a single nanoshell made of gold. Other geometries and nanostructures are investigated, and it is found that a shell of gold nanoparticles can generate similar enhancement. The concepts of composition, matrix, and satellite effects are established and studied, all of which can further increase the enhancement of the effect of X-rays.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 19, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Ting Guo
  • Publication number: 20170240872
    Abstract: A phytase having improved thermostability is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is one of mutations A to D. The mutation A is to substitute amino acids at positions 143 and 262 with cysteine, the mutation B is to substitute amino acids at positions 259 and 312 with cysteine, the mutation C is to substitute amino acids at positions 205 and 257 with cysteine, and the mutation D is to substitute amino acids at positions 264 and 309 with cysteine.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Rey-Ting Guo, Chun-Chi Chen, Ya-Shan Cheng, Tzu-Hui Wu, Jian-Wen Huang, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9718922
    Abstract: The methods disclosed herein are directed to methods of enhancing formation of a polymer from a monomer on a metal-based nanoparticle under X-ray irradiation and compositions produced by such methods. The method comprises irradiating a monomer solution with X-rays to form the polymer; wherein the monomer solution comprises the monomer, the metal-based nanoparticle, and a solvent capable of generating a hydroxyl radical; and wherein the metal-based nanoparticle is a particle having a greatest dimension between 5 and 100 nanometers. The methods also include the dissolution metal ions from these same metal-based nanoparticles wherein the solution comprises the metal-based nanoparticle and a solvent capable of generating a hydroxyl radical; and wherein the metal-based nanoparticle is a particle having a greatest dimension between 5 and 100 nanometers.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: August 1, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ting Guo, R. Andrew Davidson
  • Publication number: 20170191046
    Abstract: A lactone hydrolase having improved activity towards ?-zearalenol is disclosed. The lactone hydrolase has a modified amino acid sequence of SEQ ID NO: 5, wherein the modification is a substitution of valine at position 167 with histidine. A method of degrading ?-zearalenol using such lactone hydrolase is also disclosed.
    Type: Application
    Filed: December 1, 2016
    Publication date: July 6, 2017
    Inventors: Rey-Ting Guo, Yingying Zheng, Zhongxia Xu, Chun-Chi Chen, Wei Peng, Weidong Liu, Je-Ruei Liu, Yanhe Ma
  • Publication number: 20170183641
    Abstract: A cellulase having improved thermostability is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is adding a cysteine in N terminal and adding a glycine and a cysteine or adding a proline and a cysteine in C terminal.
    Type: Application
    Filed: December 16, 2016
    Publication date: June 29, 2017
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Patent number: 9650625
    Abstract: A pectinase having improved thermostability is disclosed. The pectinase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of serine at position 181 with phenylalanine, methionine or leucine.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: May 16, 2017
    Assignee: DONGGUAN APAC BIOTECHNOLOGY CO., LTD.
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko
  • Publication number: 20170121699
    Abstract: A pectinase having improved thermostability is disclosed. The pectinase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of serine at position 181 with phenylalanine, methionine or leucine.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 4, 2017
    Inventors: Rey-Ting Guo, Ya-Shan Cheng, Jian-Wen Huang, Tzu-Hui Wu, Hui-Lin Lai, Cheng-Yen Lin, Tsung-Yu Ko