Abstract: The present application belongs to the field of medicine, and in particular relates to a crystal of a diarylthiohydantoin compound having a structure of the following formula (I), a preparation method therefor, and use thereof in the preparation of medicaments for treating related diseases which are androgen-mediated.

Abstract: Disclosed are compounds of Formula (I), Formula (II), or a salt thereof: Formula (I) Formula (II) which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (I), Formula (II) or their salts, and methods of treating pain disorders, cough, and itch using the same.

Abstract: The present invention provides RNA aptamer probes for detection of target genetic material and methods for using the probes. In some embodiments, the invention provides devices for the detection of the target genetic material using the probes of the preset invention. In some embodiments, the invention provides methods for designing RNA aptamer probes for detection of target genetic material. In some embodiments, the target genetic material is genetic material from a pathogen. In some embodiments the pathogen is influenza virus. In some embodiments, the devices of the present invention may be used outside of laboratory setting and do not require any specialized skills. In some embodiments, the devices of the present invention are used in conjunction with a mobile phone camera.

Abstract: The present technology relates to nanomaterials and methods of their use, and more specifically to methods and structures using nanomaterials to fiducially measure radiation dosing.

Abstract: A method and a system for thermal infrared facial recognition are provided. The method includes: determining a thermal infrared facial image to be recognized; inputting the thermal infrared facial image to be recognized into a trained three-sense component extractor to position eyes, a nose, and a mouth of a face in the image, and to perform regional positioning of a left eye, a right eye, the nose, and the mouth, so as to constitute a corresponding key region group; performing affine transformation on the thermal infrared facial image to be recognized using a difference between a key region group of a standard face and the key region group of the face to be recognized; inputting a thermal infrared image after face alignment calibration into a trained facial feature extraction to extract corresponding facial features; and inputting the extracted facial features into a trained classifier to recognize information of an owner.

Abstract: Provided are a polymer containing S,S-dioxide-dibenzothiophene in backbone chain with content-adjustable triarylamine end groups, and a preparation method and an application thereof. Triarylamines hole-transport small molecules are introduced into the polymer end group, and a content of the triarylamine end groups can be adjusted by controlling a polymer molecular weight, so that the polymer has better electron-transport and hole-transport capabilities, and charge carrier transport can be balanced, so that more exciton recombination takes place effectively, thus improving the luminous efficiency and stability of the polymer. The polymer is prepared by a Suzuki polymerization reaction and does not require synthesis of new monomers. The polymer material is used for preparing highly effective and stable monolayer devices, and is dissolved directly in an organic solvent, then spin-coated, ink-jet printed, or printed to form a film.

Abstract: Described are composite photonic materials that incorporate magnetic nanoparticles inside hollow or solvent-filled nano-scale or micro-scale shells and methods of making and using such composite photonic materials. When these photonic materials are present in a magnetic field, they exhibit a change in reflected, scattered, and/or transmitted light as compared to when the materials are not in the presence of the magnetic field. This results in the materials appearing to have a different color, such as when observed by the human eye or a light detecting device, such as a camera.

Abstract: A method includes forming a first fin and a second fin on a substrate; forming a dummy gate material over the first fin and the second fin; etching the dummy gate material using a first etching process to form a recess between the first fin and the second fin, wherein a sacrificial material is formed on sidewalls of the recess during the first etching process; filling the recess with an insulation material; removing the dummy gate material and the sacrificial material using a second etching process; and forming a first replacement gate over the first fin and a second replacement gate over the second fin, wherein the first replacement gate is separated from the second replacement gate by the insulation material.

Abstract: Methods, compositions, systems and devices are provided in which zeolite particles, preferably of silicon and aluminum, are used as desiccants. In embodiments a plurality of zeolite particles are provided that are less than 1 mm in size. The particles may be arrayed such that at least some of the plurality of particles are spaced apart from each other and may be arrayed in rows and columns. Embodiments provide the particles are useful or removing water under ambient conditions and in removing water from air or material and in an embodiment removing water from plant material, such as harvested crop material, or where the dried air is contacted with plant material. Microwave radiation may be used to efficiently and in a cost effective manner dehydrate the rehydrated particles.

Abstract: The present disclosure provides systems and methods for providing irradiation energy, imaging, and detecting X-ray fluorescence from a volume in a sample. The present disclosure further relates to methods of increasing the delivery of irradiation energy to a target in a sample.

Abstract: Described are composite photonic materials that incorporate magnetic nanoparticles inside hollow or solvent-filled nano-scale or micro-scale shells and methods of making and using such composite photonic materials. When these photonic materials are present in a magnetic field, they exhibit a change in reflected, scattered, and/or transmitted light as compared to when the materials are not in the presence of the magnetic field. This results in the materials appearing to have a different color, such as when observed by the human eye or a light detecting device, such as a camera.

Abstract: An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided.

Abstract: Described are composite photonic materials that incorporate magnetic nanoparticles inside hollow or solvent-filled nano-scale or micro-scale shells and methods of making and using such composite photonic materials. When these photonic materials are present in a magnetic field, they exhibit a change in reflected, scattered, and/or transmitted light as compared to when the materials are not in the presence of the magnetic field. This results in the materials appearing to have a different color, such as when observed by the human eye or a light detecting device, such as a camera.

Abstract: Provided are a polymer containing S,S-dioxide-dibenzothiophene in backbone chain with content-adjustable triarylamine end groups, and a preparation method and an application thereof. Triarylamines hole-transport small molecules are introduced into the polymer end group, and a content of the triarylamine end groups can be adjusted by controlling a polymer molecular weight, so that the polymer has better electron-transport and hole-transport capabilities, and charge carrier transport can be balanced, so that more exciton recombination takes place effectively, thus improving the luminous efficiency and stability of the polymer. The polymer is prepared by a Suzuki polymerization reaction and does not require synthesis of new monomers. The polymer material is used for preparing highly effective and stable monolayer devices, and is dissolved directly in an organic solvent, then spin-coated, ink-jet printed, or printed to form a film.

Abstract: The present invention provides a photo alignment device, a photo alignment method and an alignment film preparation system. The photo alignment device comprises a photo alignment unit, a temperature acquisition unit and a control unit, the photo alignment unit used to perform preheating, curing and photo alignment on a film-to-be-aligned layer; the temperature acquisition unit used to perform real-time acquisition on temperatures of the film-to-be-aligned layer during the preheating, curing, and photo alignment in synchronization with the photo alignment unit, and feed the acquired temperatures back to the control unit; and the control unit used to determine whether the fed back temperatures are within preset ranges of temperature, and adjust position, power and/or speed of the photo alignment unit based on the determination result, to cause the temperatures of the film-to-be-aligned layer during the preheating, curing, and photo alignment to be within their respective preset ranges of temperature.

Abstract: A cellulase having improved enzymatic activity is disclosed. The cellulase has a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of methionine at position 120 or a corresponding position with asparagine.

Abstract: A xylosidase having improved enzymatic activity is disclosed. The amino acid sequence of the xylosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of phenylalanine at position 35 with glutamate, and/or a substitution of glutamine at position 41 with histidine.

Abstract: A lysozyme having improved enzymatic activity is disclosed. The amino acid sequence of the lysozyme is a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of histidine at position 166 or a corresponding position with lysine.

Abstract: A lactone hydrolase having improved activity towards ?-zearalenol is disclosed. The lactone hydrolase has a modified amino acid sequence of SEQ ID NO: 5, wherein the modification is a substitution of valine at position 167 with histidine. A method of degrading ?-zearalenol using such lactone hydrolase is also disclosed.

Abstract: A lysozyme having improved enzymatic activity is disclosed. The amino acid sequence of the lysozyme is a modified amino acid sequence of SEQ ID NO: 2 or a modified amino acid sequence with at least 80% sequence identity of SEQ ID NO: 2, wherein the modification is a substitution of histidine at position 166 or a corresponding position with lysine.