Abstract: Methods, kits, and compositions are provided herein that can be used to treat hematopoietic disorders using an anti-CD47 agent such as an antibody and a hypomethylating agent, such as azacitidine.

Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.

Abstract: A wearable device utilizing flexible electronics is disclosed. The wearable device may comprise a flexible matrix material and may include sensors for measuring biometric measurements of an individual, an accelerometer for measuring an acceleration of a body part to which the wearable device is attached, a wireless transmitter, a flexible power source, and a microcontroller. During an activity, the microcontroller may receive signals from the sensors including the biometric measurements, and signals from the accelerometer including acceleration and force measurements associated with the individual. The microcontroller may convert the signals into digital signals and transmit the signals to a computing device for analysis. The computing device may analyze the digital signals to determine a performance metric for the individual. The performance metric may be compared to baseline data for the individual to determine a fatigue level, injury risk, or an adjustment to be made by the individual during the activity.

Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath with a tubular inner liner wound in a spiral configuration such that a plurality of protrusions is disposed in an overlapping portion of the sheath. The disclosed sheath is configured to expand from a predetermined rest diameter dr to an expanded diameter de during application of a radial outward force by passage of a medical device through the sheath.

Abstract: The present disclosure relates to antibodies that selectively bind to CD3 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Abstract: A flash memory physical interface in a host device may be configured based on a selection signal indicating whether a flash memory system is a first type or a second type. Based on the selection signal, either a first differential memory data signal input of driver circuitry or a second differential memory data signal input of the driver circuitry may be coupled to a differential data input of the flash memory system. Based on the selection signal, a differential data output of the flash memory system may be coupled to either a first differential memory data signal output of receiver circuitry or a second differential memory data signal output of the receiver circuitry.

Abstract: The electronic apparatus includes a processor, a memory, a signal generation circuit and a vibration generator. The processor executes a program. The memory stores the program. The signal generation circuit generates a beep signal for generating a beep sound. The vibration generator generates the vibrations on the basis of the beep signal.

Abstract: Provided is a method for encryption key generation and authentication, based on a gait characteristic. In the method for encryption key generation and authentication, based on a gait characteristic, gait data for the gait of a user is received from a user terminal, a user encryption key for each user is generated with respect to each service, based on the gait data, authentication encryption key is generated based on gait data to be authenticated, the user encryption key is compared with the authentication encryption key, the user is authenticated, when the user encryption key matches the authentication encryption key.

Abstract: An automated system that can be used for prosthetic heart valve manufacturing or suturing procedures. The system can include a first automated fixture that includes an articulating arm and a target device holder. The system can also include one or more additional automated fixtures, which can be configured as one or more suturing arms that include another articulating arm and a needle holder. The first automated fixture can be configured to rotate a target device held by the holder to allow the one or more additional automated fixtures to perform operations such as form sutures on the target device without intervention of a human operator. The system can include a display system configured to display status information of a suturing procedure.

Abstract: In one example, a non-volatile memory system, comprises an array of non-volatile memory cells arranged in rows and columns, each non-volatile memory cell comprising a source and a drain; a plurality of bit lines, each of the plurality of bit lines coupled to the drain or each non-volatile memory cell in a column of non-volatile memory cells; a source line coupled to the source of each non-volatile memory cell; and an adaptive bias decoder for providing a voltage to an erase gate line of the array during an operation, wherein the adaptive bias decoder adjusts the voltage provided to the erase gate line in response to changes in a voltage of the source line.

Abstract: Disclosed herein are image-based object recognition method and system by and in which a learning server performs image-based object recognition based on the learning of environment variable data. The image-based object recognition method includes: receiving an image acquired through at least one camera, and segmenting the image on a per-frame basis; primarily learning labeling results for one or more objects in the image segmented on a per-frame basis; performing primary reasoning by performing object detection in the image through a model obtained as a result of the primary learning; performing data labeling based on the results of the primary reasoning, and performing secondary learning with weights allocated to respective boxes obtained by the primary reasoning and estimated as object regions; and finally detecting one or more objects in the image through a model generated as a result of the secondary learning.

Abstract: Dynamic allocation of power modules for charging electric vehicles is described herein. The charging system includes multiple dispensers that each include one or more power modules that can supply power to any one of the dispensers at a time. A dispenser includes a first power bus that is switchably connected to one or more local power modules and switchably connected to one or more power modules located remotely in another dispenser. The one or more local power modules are switchably connected to a second power bus in the other dispenser. The dispenser includes a control unit that is to cause the local power modules and the remote power modules to switchably connect and disconnect from the first power bus to dynamically allocate the power modules between the dispenser and the other dispenser.

Abstract: A laser system for creating patterns on clothing includes a laser source; a phased array acousto-optic deflector (AOD) configured to control the direction and intensity of the laser beam; a computer comprising software for reading input files containing pattern designs and controlling the AOD to direct the laser beam according to the pattern designs; a fabric preparation station for washing and preparing fabric before laser treatment; a post-laser wash station for removing debris from the fabric after laser treatment; and a clothing finishing station for applying finishing touches to the fabric. The AOD includes an optical element having a surface with one or more steps formed thereon; a conductive layer formed on the surface with the steps; one or more crystals secured to each step; and electrodes positioned on each surface of each crystal.

Abstract: A vehicle alarm system configured to avoid false alarms while maintaining the vehicle alarm system armed. The vehicle alarm system includes: at least a first sensor configured to detect at least a first living object; a processing circuitry operatively connected to the least a first sensor configured to cause the vehicle alarm system to: detect at least a first living object inside of a vehicle by the at least first sensor; and reduce, or unarm, at least a first alarm function of the vehicle alarm system in response to detecting the at least first living object, while at least a second alarm function of the vehicle alarm system is configured to be armed.

Abstract: Introduced here computer programs and associated computer-implemented techniques for generating measurements of physical structures and environments in an automated matter through analysis of data that is generated by one or more sensors included in a computing device. This can be accomplished by combining insights that are derived through analysis different types of data that are generated, computed, or otherwise obtained by a computing device. For instance, a computer program may enable or facilitate measurement of arbitrary dimensions, angles, and square footage of a physical structure based on (i) images generated by an image sensor included in the corresponding computing device and (ii) measurements generated by an inertial sensor included in the corresponding computing device.

Abstract: A system for tracking passenger behaviors of passengers on a commercial passenger vehicle is provided. The system comprises: media playback devices located on the commercial passenger vehicle, the media playback devices being associated with passenger seats and configured to operate in an onboard check-in mode, and an onboard server in communication with the media playback devices and configured to receive, from a media playback device associated with a passenger seat of a passenger, passenger identification information of the passenger and update passenger boarding information to indicate a completion of a boarding process of the passenger. The onboard server is further configured to provide, to at least one of a ground terminal or a crew terminal, passenger boarding information that enables determination of a time interval between a start of the boarding process by each passenger and an end of the boarding process as indicated from the media playback devices.

Abstract: Disclosed are methods and apparatus for treating weeds, and more specifically treating weeds by use of microwaves.

Abstract: A prosthetic heart valve includes an annular frame that is radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The frame has a plurality of circumferentially extending rows of angled struts, each row of angled struts comprising angled struts arranged in a zig-zag pattern. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame. The sealing member has an undulating outflow edge portion forming a plurality of triangular projections that are connected to and shaped to correspond to the zig-zag pattern of one of the rows of angled struts. The outer sealing member is sized to fit snugly against the outer surface of the frame when the frame is in the expanded configuration.