Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Abstract: A system includes a transceiver to communicate with a predetermined target; one or more antennas coupled to the transceiver each electrically or mechanically steerable to the predetermined target; and an edge processing module coupled to the transceiver and one or more antennas to provide low-latency computation for the predetermined target.

Abstract: Provided are a floating-point unit, a system, and method for generating binary integer output or floating-point output based on a selector. A first input operand, a second input operand, a third input operand, and a result format selector value are received. The first input operand, the second input operand, and the third input operand comprise floating-point values. The first input operand, the second input operand, and the third input operand are processed to produce a final result comprising one of a binary integer value and a floating point value based on the result format selector value.

Abstract: An anode active material and a high-capacity secondary battery for high speed charging including the same are described. When an anode active material including a composite material in which a high-capacity silicon-based anode active material and a graphite active material capable of enabling high-speed charging by increasing the interlayer distance are mixed is used as an anode, the high-speed charging performance of a secondary battery can be improved and the capacity thereof can be increased, and a secondary battery that can be mounted on small and medium-sized electronic devices such as portable phones and the like, various electric mobilities including commercial electric vehicles, and energy storage systems (ESS) can be provided.

Abstract: The present disclosure describes a model for large scale color prediction of objects identified in images. Embodiments of the present disclosure include an object detection network, an attention network, and a color classification network. The object detection network generates object features for an object in an image and may include a convolutional neural network (CNN), region proposal network, or a ResNet. The attention network generates an attention vector for the object based on the object features, wherein the attention network takes a query vector based on the object features, and a plurality of key vector and a plurality of value vectors corresponding to a plurality of colors as input. The color classification network generates a color attribute vector based on the attention vector, wherein the color attribute vector indicates a probability of the object including each of the plurality of colors.

Abstract: Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state. In some embodiments, the covering feature includes a tip mounted to the spindle. The tip can include an overhang region for selectively covering a portion of the stented prosthetic heart valve. In other embodiments, the tip can include a tip body and a compressible foam bumper. In yet other embodiments, the covering feature includes an outer sheath arranged to selectively cover the stented prosthetic heart valve. The outer sheath can be elastic and stretchable for recapturing a partially expanded prosthesis, for example by including one or more windows covered by a stretchable covering layer.

Abstract: Methods and apparatus for processing signals captured by one or more sensors are disclosed. An example method includes receiving a first signal from a control circuit, the first signal including control data associated with the one or more sensors, recovering a fixed frequency clock signal and a control signal from the first signal, generating a spread spectrum clock signal based on the fixed frequency clock signal, receiving a sensor data signal based at least in part on data captured by the one or more sensors, the spread spectrum clock signal, and the control signal, retiming the sensor data signal based at least in part on the spread spectrum clock signal and the fixed frequency clock signal, and generating an output signal based on the retimed sensor data signal.

Abstract: Utilization of a selection ring to select icons is provided herein. The selection ring is presented in a first graphical user interface. In response to receiving a first selection of the selection ring by a user, a plurality of icons are presented in the first graphical user interface. User manipulation of a position of the selection ring within the first graphical user interface is received, where that manipulation occurs without altering a location of the plurality of icons being presented within the first graphical user interface. In response to receiving a second selection associated with the selection ring, an icon from the plurality of icons is selected based on the position of the selection ring within the first graphical user interface. A second graphical user interface is then presented to the user based on the selected icon.

Abstract: Systems and methods for independently managing wireless transmission by individual spectrum access systems in a radio frequency spectrum shared by a plurality of spectrum access systems. An example method includes: receiving, by the spectrum access system, an interference budget from a sensor; determining, by the spectrum access system, secondary users managed by the spectrum access system in a radio frequency spectrum shared by a plurality of spectrum access systems; managing a move list for the spectrum access system independently of the other spectrum access systems in an absence of exchange of spectrum grant information with the other spectrum access systems; and determining the move list for the spectrum access system from a first moment and a second moment of an aggregate interference distribution such that the spectrum access system provides grants to its secondary users in a dynamic protection area of the spectrum access system.

Abstract: The present document describes an electronic device with a structural midframe and associated methods. The architectural design of the electronic device (e.g., a security camera) is such that its components are assembled onto the midframe to form a subassembly and the housing is assembled after the subassembly. The midframe includes various features that enable multiple printed circuit boards, a camera subassembly, a front housing member, a heatsink, and a heat spreader to be assembled onto the midframe outside of the housing. The midframe can also include a hinge-bearing surface forming a portion of a ball joint for supporting rotational movement of the electronic device. Accordingly, the electronic device uses the midframe, rather than the housing, as a structural member.

Abstract: A method for system for creation of augmented reality group simulated spaces. The method includes: training an artificial intelligence system to mesh first and second sets of images into group images, and mesh the first set of measurements and the second set of measurements into group measurements; calculating a group simulated space that is a virtual representation of the common physical space using the group images and the group measurements; enabling a user to enter a multi-dimensional fabric user interface; enabling users that are members of the user group to access the group portal in the multi-dimensional fabric user interface and enter the group simulated space; preventing users that are not members of the user group from accessing the group portal; and enabling the users of the user group to interact with virtual objects and other users of the user group in the group simulated space.

Abstract: Methods, kits, and compositions are provided herein that can be used to treat hematopoietic disorders using an anti-CD47 agent such as an antibody and a hypomethylating agent, such as azacitidine.

Abstract: A wearable device utilizing flexible electronics is disclosed. The wearable device may comprise a flexible matrix material and may include sensors for measuring biometric measurements of an individual, an accelerometer for measuring an acceleration of a body part to which the wearable device is attached, a wireless transmitter, a flexible power source, and a microcontroller. During an activity, the microcontroller may receive signals from the sensors including the biometric measurements, and signals from the accelerometer including acceleration and force measurements associated with the individual. The microcontroller may convert the signals into digital signals and transmit the signals to a computing device for analysis. The computing device may analyze the digital signals to determine a performance metric for the individual. The performance metric may be compared to baseline data for the individual to determine a fatigue level, injury risk, or an adjustment to be made by the individual during the activity.

Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.

Abstract: The present disclosure relates to antibodies that selectively bind to CD3 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Abstract: An automated system that can be used for prosthetic heart valve manufacturing or suturing procedures. The system can include a first automated fixture that includes an articulating arm and a target device holder. The system can also include one or more additional automated fixtures, which can be configured as one or more suturing arms that include another articulating arm and a needle holder. The first automated fixture can be configured to rotate a target device held by the holder to allow the one or more additional automated fixtures to perform operations such as form sutures on the target device without intervention of a human operator. The system can include a display system configured to display status information of a suturing procedure.

Abstract: The electronic apparatus includes a processor, a memory, a signal generation circuit and a vibration generator. The processor executes a program. The memory stores the program. The signal generation circuit generates a beep signal for generating a beep sound. The vibration generator generates the vibrations on the basis of the beep signal.

Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath with a tubular inner liner wound in a spiral configuration such that a plurality of protrusions is disposed in an overlapping portion of the sheath. The disclosed sheath is configured to expand from a predetermined rest diameter dr to an expanded diameter de during application of a radial outward force by passage of a medical device through the sheath.

Abstract: In one example, a non-volatile memory system, comprises an array of non-volatile memory cells arranged in rows and columns, each non-volatile memory cell comprising a source and a drain; a plurality of bit lines, each of the plurality of bit lines coupled to the drain or each non-volatile memory cell in a column of non-volatile memory cells; a source line coupled to the source of each non-volatile memory cell; and an adaptive bias decoder for providing a voltage to an erase gate line of the array during an operation, wherein the adaptive bias decoder adjusts the voltage provided to the erase gate line in response to changes in a voltage of the source line.