Patents by Inventor Toby Freyman

Toby Freyman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944724
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 2, 2024
    Assignee: ARSENAL MEDICAL, INC.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Publication number: 20230414840
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: September 12, 2023
    Publication date: December 28, 2023
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 11786642
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: October 17, 2023
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
  • Publication number: 20220105248
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: December 13, 2021
    Publication date: April 7, 2022
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Patent number: 11246964
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: February 15, 2022
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 10980920
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: April 20, 2021
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 10888639
    Abstract: Delivery catheters for in situ forming foams are provided. The catheters include, in various embodiments, coatings, valves, mixing structures, exit ports and combinations of the same.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: January 12, 2021
    Assignee: Arsenal Medical, Inc.
    Inventors: Toby Freyman, Jennifer Mortensen, Jeffrey Groom, II
  • Publication number: 20200405921
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: August 7, 2020
    Publication date: December 31, 2020
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
  • Patent number: 10765781
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: September 8, 2020
    Assignee: Arsenal Medical Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P Pham, Changcheng You, Jeffrey D. Carbeck
  • Patent number: 10687795
    Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: June 23, 2020
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
  • Patent number: 10682436
    Abstract: Systems and methods related to polymer foams for the treatment of blood vessel dissections are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to or within a dissection caused by an intimal tear in a blood vessel, sealing the dissection and preventing further perfusion thereof. In some embodiments, the polymer foam can be formed within a body cavity (i.e., in-situ foam formation). The foam may be used to fill the dissection as a thrombosing agent. In addition, the foam may be used in conjunction with medical devices such as stents, stent-grafts, balloons, and catheters.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: June 16, 2020
    Assignee: Arsenal Medial, Inc.
    Inventors: Toby Freyman, Meghan McGill
  • Patent number: 10420862
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: September 24, 2019
    Assignee: Aresenal AAA, LLC.
    Inventors: Upma Sharma, Gregory Zugates, Rany Busold, Toby Freyman
  • Publication number: 20190240380
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: April 5, 2019
    Publication date: August 8, 2019
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Patent number: 10307515
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: June 4, 2019
    Assignee: Arsenal Medical Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Publication number: 20180250446
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: March 16, 2018
    Publication date: September 6, 2018
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Publication number: 20180064855
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: July 6, 2017
    Publication date: March 8, 2018
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
  • Patent number: 9883865
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: February 6, 2018
    Assignee: ARSENAL MEDICAL, INC.
    Inventors: Toby Freyman, Joseph Lomakin, John Marini, Jennifer Mortensen, Adam Rago, Rany Busold, Upma Sharma, Gregory T. Zugates
  • Publication number: 20170325796
    Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.
    Type: Application
    Filed: January 20, 2017
    Publication date: November 16, 2017
    Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
  • Patent number: 9700656
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: July 11, 2017
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changchen You, Jeffrey D. Carbeck
  • Patent number: 9655864
    Abstract: The present invention relates generally to the field of electrospun fibers. In particular, the present invention relates to core-sheath fibers and related electrospinning methods. The fibers of the invention comprise poorly water soluble drugs and/or proteins.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 23, 2017
    Assignee: Arsenal Medical, Inc.
    Inventors: Toby Freyman, Quynh Pham, Robert F. Mulligan, Abby N. Picard, Xuri Yan