Abstract: A shoe or footwear insert pad is configured to fit over at least part of the forward portion of the sole, extending under the toes and ball of a wearer's foot. The pad has an upper face, a lower face, a forward edge, a rear edge, and inner and outer edges, with the inner and outer edges conforming to the shape of corresponding inner and outer edges of the sole of the footwear. A foot stop bar or rib on the inner face of the pad extends in a selected, at least partially curved path from the inner edge to the outer edge configured to match the curve of the space at the base of a wearer's toes where the toes meet the remainder of the foot. In one example, the position of the foot stop bar on the pad is adjustable for wearers' having different foot sole topographies.

Abstract: This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.

Abstract: An elongated handle has a pointed fish hook rotatably affixed to one end of the handle, the hook having two operating dispositions, a first disposition wherein the hook is open for gaffing purposes and a second disposition wherein the hook folded back against the handle to block the hook point for safety. A mechanism releasably secures the hook at either disposition. A button actuated mechanism releases the hook from either disposition so that the hook can be moved from one operating disposition to the other. Preferably the gaff further includes a bias for urging the hook toward its open, gaffing disposition.

Abstract: The present invention relates to curved focal plane arrays. More specifically, the present invention relates to a system and method for making solid-state curved focal plane arrays from standard and high-purity devices that may be matched to a given optical system. There are two ways to make a curved focal plane arrays starting with the fully fabricated device. One way, is to thin the device and conform it to a curvature. A second way, is to back-illuminate a thick device without making a thinned membrane. The thick device is a special class of devices; for example devices fabricated with high purity silicon. One surface of the device (the non VLSI fabricated surface, also referred to as the back surface) can be polished to form a curved surface.

Abstract: Two counter-rotating, intermeshing, toothed wheels grind opposite sides of an interposed blade to create or burrlessly sharpen a knife-edge on the blade. The wheels can be solid or comprised of a fixed stack of toothed disks, concentrically aligned, the teeth of each succeeding disk angularly offset in a common direction from the teeth of the next preceding disk to create a wheel having a plurality of uniform, elongated composite teeth around the circumference of the stack, the teeth being angled from the wheel's axis. Two such wheels, one with teeth angled in an opposite direction, can be counter-rotated and because of the oppositely angled teeth, are capable of intermeshing. The degree of intermeshing can be selectively varied to correspondingly vary the sharpening angle. The apex ridges of both the solid and composite teeth can be selectively profiled to sharpen non-uniformly, e.g. serrating a blade edge.

Abstract: The present invention relates to improved methods for the incorporation of DNA into the genome of a Zea mays plant based on a D-alanine or D-serine selection. Preferably the transformation is mediated by Agrobacterium.

Abstract: Carbosilane-containing polymers (including oligomers) having the following structural features: greater than one repeat unit; at least 4 Si-arylene bonds; at least 1 (meth)acrylate moiety, Si—H moiety, or both; no Si—O bonds; preferably at least 4 silicon atoms; wherein 2 silicon atoms are separated by one arylene group in each repeat unit.

Abstract: This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including contraception and treatment of benign or malignant neoplastic diseases, having the general structure: wherein R1 and R2 may be single substituents or fused to form spirocyclic rings.

Abstract: Organic electroluminescent device can be formed with multiple layers including an electrode, an emission layer, and a buffer layer. The emission layer includes a light emitting material. The buffer layer is disposed between and in electrical communication with the electrode and the emission layer and includes a triarylamine hole transport material and an electron acceptor material. The buffer layer optionally includes one or more of a) a polymeric binder, b) a color converting material, and c) light scattering particles. The buffer layer can also be formed using a polymeric hole transport material having a plurality of triarylamine moieties.

Abstract: Organic polymers for use in electronic devices, wherein the polymer includes repeat units of the formula: wherein: each R1 is independently H, an aryl group, Cl, Br, I, or an organic group that includes a crosslinkable group; each R2 is independently H, an aryl group or R4; each R3 is independently H or methyl; each R5 is independently an alkyl group, a halogen, or R4; each R4 is independently an organic group that includes at least one CN group and has a molecular weight of about 30 to about 200 per CN group; and n=0-3; with the proviso that at least one repeat unit in the polymer includes an R4. These polymers are useful in electronic devices such as organic thin film transistors.

Abstract: This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including contraception and treatment of benign or malignant neoplastic diseases, having the general structure: wherein R1 and R2 may be single substituents or fused to form spirocyclic rings.

Abstract: A copolymeric material is described that is suitable for use in a hole transport layer of organic electroluminescent device. The copolymeric material contains a phosphorous-containing group selected from a phosphate or phosphonate group and tertiary amino group selected from a triarylamino group or carbazolyl group.

Abstract: Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: wherein R1, R2, R3, R4, R5, and Q1 are defined herein.

Abstract: Provided is an organic thin film transistor comprising a polymeric layer interposed between a gate dielectric and an organic semiconductor layer. Various homopolymers, copolymers, and functional copolymers are taught for use in the polymeric layer. An integrated circuit comprising a multiplicity of thin film transistors and methods of making a thin film transistor are also provided. The organic thin film transistors of the invention typically exhibit improvement in one or more transistor properties.

Abstract: Provided is an organic thin film transistor comprising a polymeric layer interposed between a gate dielectric and an organic semiconductor layer. Various homopolymers, copolymers, and functional copolymers are taught for use in the polymeric layer. An integrated circuit comprising a multiplicity of thin film transistors and methods of making a thin film transistor are also provided. The organic thin film transistors of the invention typically exhibit improvement in one or more transistor properties.

Abstract: This invention provides a progesterone receptor antagonist of formula 1 having the structure wherein, T is O, S, or absent; R1, and R2 are each, independently, hydrogen, alkyl, substituted alkyl; or R1 and R2 are taken together form a ring and together contain —CH2(CH2)nCH2—, —CH2CH2CMe2CH2CH2—, —O(CH2)pCH2—, —O(CH2)qO—, —CH2CH2OCH2CH2—, or —CH2CH2NR7CH2CH2—; n=1-5; p=1-4; q=1-4; R3 is hydrogen, OH, NH2, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, or CORA; RA is hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R4 is hydrogen, halogen, CN, NH2, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R5 is hydrogen, alkyl, or substituted alkyl; R6 is hydrogen, alkyl, substituted alkyl, or CORB; RB is hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R7 is hydrogen or alkyl; or a pharmaceutically acceptable salt thereof.

Abstract: Imidazole derivatives, compositions containing them, methods of preparing them, including regioselective scale-up synthetic methods, and methods of using them.

Abstract: Disclosed herein is an accelerometer and/or displacement device that uses a mass coupled to a rhomboidal flexure to provide compression to an optical sensing element preferably having a fiber Bragg grating (FBG). The transducer includes a precompressed optical sensor disposed along a first axis between sides of the flexure. The top portion of the flexure connects to the mass which intersects the flexure along a second axis perpendicular to the first axis. When the mass experiences a force due to acceleration or displacement, the flexure will expand or contract along the second axis, which respectively compresses or relieves the compression of the FBG in the optical sensing element along the first axis. Perturbing the force presented to the FBG changes its Bragg reflection wavelength, which is interrogated to quantify the dynamic or constant force.

Abstract: Processes for positioning, securing, and repositioning payload assemblies onto floor assemblies are disclosed. In one embodiment, a method includes forming a support structure having a plurality of elongated engagement members, each engagement member including an engagement surface adapted to support a load; forming an adaptable payload assembly that includes a payload member and at least one payload support coupled to the payload member, the payload support being adapted to transmit loads from the payload member to at least one engagement member, the payload support being moveable with the payload member relative to the support structure; and removeably coupling the payload support to at least one of the engagement surfaces of the engagement members. In an alternate embodiment, the engagement surfaces are at least one of approximately flush with and recessed below a lower surface of a panel supported by the support structure.

Abstract: Non-protruding seat track apparatus and methods are disclosed. In one embodiment, a track includes an elongated support having a support surface and an engagement surface. The support surface is adapted to engage a lower surface of a floor panel, and the engagement surface is adapted to be coupled to a payload assembly. The engagement surface is at least one of flush with and recessed below the lower surface of the floor panel when the support surface is engaged with the lower surface. The engagement surface may have at least one of an engagement slot and an attachment aperture disposed therein.