Abstract: A shoe that grows comprises a sole having a toe, medial side, lateral side, and heel. The toe of the sole extends outwardly to form a toe cap. A vamp member is adjustably connected to a free end of the toe cap. At least one medial strap connects the vamp member to the medial side of the sole. At least one lateral strap connects the vamp member to the lateral side of the sole. An adjustable heel strap connects to the medial and lateral sides of the sole and extends around the heel of the sole.

Abstract: A micronozzle device can include at least one layer having a plurality of nozzle exits for delivering a mixture of a first fluid and a second fluid, at least one first-fluid header layer having a plurality of first microchannels for receiving the first fluid, at least one first-fluid via layer adjacent the at least one first-fluid header layer to receive the first fluid and direct it to respective ones of the plurality of nozzle exits, at least one second-fluid header layer having a plurality of second microchannels for receiving the second fluid, at least one second-fluid via layer adjacent the at least one second-fluid header layer to receive the second fluid and direct it respective ones of the plurality of nozzle exits, and a plurality of first curtain-gas nozzles located at a first side of the micronozzle device and a plurality of second curtain-gas nozzles located at a second side of the micronozzle device.

Abstract: Air and fuel are directed from a burner outlet into a furnace process chamber in streams concentric on an axis, including an annular peripheral stream that includes fuel gas and adjoins products of combustion in the process chamber.

Abstract: The present invention generally relates to a method and system for retrieving search results. More particularly, the present invention relates to a method and system for retrieving search results concurrently from multiple disparate databases, whether such databases be available through the Web, or other proprietary internal networks. In an exemplary embodiment, the system includes a user interface, a control engine, and a number of translators which are used to communicate with a number of corresponding databases. During exemplary operation, a user uses the user interface to enter search term(s) and other pertinent information relating to his/her search and specify which ones of the databases are to be searched. The search term(s) and other pertinent information are then relayed to the control engine which, in turn, forwards them to the appropriate translators which correspond to the specified databases to be searched.

Abstract: A system for implanting an anchor into bone, the system comprising a curved cannulated guide for percutaneous insertion, having a proximal end and a distal end; a flexible drill insertable through the curved guide from the proximal end to the distal end, the flexible drill having a shaft having a flexible portion; and a flexible inserter for inserting a suture anchor into a bore at the anatomical site formed by the flexible drill, the flexible inserter having a shaft having a flexible portion, wherein the flexible portions of both the flexible drill and flexible inserter include a series of discrete, interlocking segments.

Abstract: A crowd sourced estimation system provides crowd sourced estimates from one or more estimators that are selected based on one or more predefined criteria. In operation, a user may request and estimate for a property identified by a property identifier. The estimation system may then transmit estimate requests to the selected estimators and generate an aggregate estimate from the estimates received from the estimators as a result. The aggregate estimate is then communicated to the user. The predefined criteria may include location or distance from the property for which an estimate is to be generated.

Abstract: A fluid micro-mixer apparatus includes a plurality of first microchannels for receiving a first fluid and a plurality of second microchannels for receiving a second fluid. A mixing chamber flow path is disposed to receive the first and second fluids after the first and second fluids exit their respective output ports. The mixing chamber flow path can include a first mixing chamber in the vicinity of the respective output ports, and the mixing chamber flow path can separate into at least two different flow paths downstream from the first mixing chamber.

Abstract: A therapeutic thumb wrap is provided. The thumb wrap includes a body having an inner fabric layer and an outer fabric layer attached together by a seam. At least one pocket is formed in between the inner and outer fabric layers. A plurality of dried seeds is disposed within the pocket. The body includes a thumb portion with a first side extending downward from the thumb portion and a second side opposite the first side extending downward from the thumb portion. The first side and the second side are sized to wrap around a wrist of the user. A connector may releasably attach the first side to the second side, securing the thumb wrap to the user's wrist.

Abstract: The present disclosure concerns embodiments of a microfluidic transfer device. The device mitigates risk of cross contamination between working fluids and is amenable to high-volume, low-cost manufacturing techniques. The device may be configured for mass transfer, heat transfer, or both. For instance, certain disclosed embodiments incorporate semi-permeable membranes to transfer target substances from one fluid to another. Moreover, the device may incorporate both heat and mass transfer components.

Abstract: A system for removably attaching a decorative element to a garment or other accessory, including a panel bearing a graphic design, and a pair of mounting pads to which the panel can be attached. First and second pin members are disposed at opposing edges of the panel, each pin member having a pin extending for a length parallel to that edge. The mounting pads are attachable to a garment or accessory item. Each mounting pad has a longitudinal tunnel suitable to accommodate one of the pins. The mounting pads may be attached on the outside of an article, or on the interior of an article so that only the tunnel is exposed at the exterior of the article, in a recessed manner. The system allows a decorative panel to be interchangeably facilitates their attachment to a wide range of apparel and accessory items.

Abstract: A micronozzle device can include at least one layer having a plurality of nozzle exits for delivering a mixture of a first fluid and a second fluid, at least one first-fluid header layer having a plurality of first microchannels for receiving the first fluid, at least one first-fluid via layer adjacent the at least one first-fluid header layer to receive the first fluid and direct it to respective ones of the plurality of nozzle exits, at least one second-fluid header layer having a plurality of second microchannels for receiving the second fluid, at least one second-fluid via layer adjacent the at least one second-fluid header layer to receive the second fluid and direct it respective ones of the plurality of nozzle exits, and a plurality of first curtain-gas nozzles located at a first side of the micronozzle device and a plurality of second curtain-gas nozzles located at a second side of the micronozzle device.

Abstract: Provided herein are compounds having a structure selected from among Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V) and Formula (VI) that are androgen receptor modulators and/or androgen receptor binding agents. Also disclosed are methods of making and using such compounds, including, but not limited to, using such compounds for treating various conditions.

Abstract: An apparatus for inserting a suture anchor into an internal anatomical site through a cannula, or percutaneously, has a curved hollow guide for insertion into the cannula and/or tissue. The guide has a proximal end and a distal end. The distal end has a “parabolic” shape for engaging the intended anatomical site such as a glenoid. A flexible obturator is insertable through the curved guide from the proximal end to the distal end to facilitate insertion of the guide through the cannula. A flexible drill is insertable through the curved guide from the proximal to the distal end once the guide is in place. A flexible inserter is provided for inserting a suture anchor into a bore at the anatomical site formed by the flexible drill.

Abstract: A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.

Abstract: Systems and methods enable remote (or “off-campus”) users complete authorized access to full-record content of 3rd-party databases subscribed to by the user's institution. More particularly, the present invention relates to a method and system that acts as a transparent conduit between the user and a remote database, managing relevant session/context information without the user's awareness and without the need for users to install plug-ins or configure browser proxies.

Abstract: A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.

Abstract: A system and method for automatically adapting digital message traffic flow evaluates message delivery disposition, latency and performance metrics such that the system operates more optimally in terms of both overall throughput as well as with respect to system sending reputation. Reputation is in the context of maintaining message flow within limits that are acceptable for a given destination, such that the sender behavior avoids being flagged as abusive or otherwise undesirable.

Abstract: A metering valve includes a valve body, a flow tube, an orifice plate, a central flow body, and a mover. The valve body has an inlet and an outlet. The flow tube is carried for axial movement in slidable and sealing engagement with the valve body at an inlet end and an outlet end. The orifice plate has an outlet. The central flow body is provided on an upstream end of the orifice plate and has an annular seal configured to seat into engagement with the outlet end of the flow tube when the flow tube is moved to a downstream position. The central flow body also includes a central, protruding flow diverter upstream and central of the annular seal. The mover is provided in the valve body and is configured to carry the flow tube for displacement of the output end toward and away from the central flow body.