Patents by Inventor Todd Zachary DESANTIS

Todd Zachary DESANTIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEINS FOR THE TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
    Publication number: 20200148728
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: April 6, 2018
    Publication date: May 14, 2020
    Inventors: Andrew Wonhee Han, Andrew Whitman Goodyear, Tarunmeet Gujral, Todd Zachary Desantis, Karim Dabbagh, Toshihiko Takeuchi, Ye Jin, Michi Izumi Willcoxon, Stefanie Banas
  • PROTEINS FOR THE TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
    Publication number: 20200061152
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: May 4, 2018
    Publication date: February 27, 2020
    Inventors: Andrew Wonhee Han, Andrew Whitman Goodyear, Tarunmeet Gujral, Todd Zachary DeSantis, Karim Dabbagh
  • LEVERAGING SEQUENCE-BASED FECAL MICROBIAL COMMUNITY SURVEY DATA TO IDENTIFY A COMPOSITE BIOMARKER FOR COLORECTAL CANCER
    Publication number: 20200011873
    Abstract: The present disclosure provides fecal microbial markers for diagnosing colorectal cancer and colorectal adenoma. The present disclosure also provides methods for diagnosing colorectal cancer and colorectal adenoma using these intestinal microbial markers.
    Type: Application
    Filed: March 16, 2018
    Publication date: January 9, 2020
    Inventors: Todd Zachary Desantis, Thomas Weinmaier, Manasi Sanjay Shah, Emily Brooke Hollister-Branton
  • Proteins for the treatment of epithelial barrier function disorders
    Patent number: 10251933
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: April 9, 2019
    Assignee: Second Genome, Inc.
    Inventors: Andrew Wonhee Han, Andrew Whitman Goodyear, Tarunmeet Gujral, Todd Zachary Desantis, Karim Dabbagh, Toshihiko Takeuchi, Ye Jin, Michi Izumi Willcoxon, Stefanie Banas
  • PROTEINS FOR THE TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
    Publication number: 20180289770
    Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: April 6, 2018
    Publication date: October 11, 2018
    Inventors: Andrew Wonhee HAN, Andrew Whitman GOODYEAR, Tarunmeet GUJRAL, Todd Zachary DESANTIS, Karim DABBAGH, Toshihiko TAKEUCHI, Ye JIN, Michi Izumi WILLCOXON, Stefanie BANAS