Patents by Inventor Tohru Tanaka

Tohru Tanaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETECTION OF UROTHELIAL CANCER
    Publication number: 20130095520
    Abstract: It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these to a test subject, collecting urine from the test subject, and detecting the presence of fluorescence or amount of fluorescence in the collected urine.
    Type: Application
    Filed: June 20, 2011
    Publication date: April 18, 2013
    Applicants: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY, SBI PHARMACEUTICALS CO., LTD.
    Inventors: Keiji Inoue, Taro Shuin, Mutsuo Furihata, Yoshihiko Hirao, Tohru Tanaka
  • THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES
    Publication number: 20130011337
    Abstract: To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ?-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Applicant: SBI PHARMACEUTICALS CO., LTD.
    Inventors: Toshihiko KUROIWA, Yoshinaga KAJIMOTO, Takahiro MASUBUCHI, Masahiro ISHIZUKA, Tohru TANAKA
  • Polyphenol-content-increasing agent for plant
    Patent number: 8309493
    Abstract: To provide a polyphenol-content-increasing agent which increases the content of polyphenol in a plant. A polyphenol-content-increasing agent for plant, containing, as an active ingredient, a 5-aminolevulinic acid or a derivative thereof represented by the following formula (1): (Chem 1) R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group which may have a substituent, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group, or a salt thereof.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: November 13, 2012
    Assignee: Cosmo Oil Co., Ltd.
    Inventors: Masao Kondo, Naomi Aiba, Setsuko Miyanari, Masahiro Ishizuka, Tohru Tanaka
  • 5-AMINOLEVULINIC ACID SALT, PROCESS FOR PRODUCING THE SAME AND USE THEREOF
    Publication number: 20120172227
    Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.
    Type: Application
    Filed: March 13, 2012
    Publication date: July 5, 2012
    Applicant: COSMO OIL CO., LTD
    Inventors: Naohisa TACHIYA, Seiji NISHIKAWA, Mai HIGO, Tohru TANAKA, Masahiro ISHIZUKA, Hideki OKADA
  • 5-aminolevulinic acid salt, process for producing the same and use thereof
    Patent number: 8173839
    Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: May 8, 2012
    Assignee: Cosmo Oil Co., Ltd
    Inventors: Naohisa Tachiya, Seiji Nishikawa, Mai Higo, Tohru Tanaka, Masahiro Ishizuka, Hideki Okada
  • Method for producing 5-aminolevulinic acid hydrochloride
    Patent number: 8148574
    Abstract: A method for producing crystals of 5-aminolevulinic acid hydrochloride wherein, in carrying out adsorption of 5-aminolevulinic acid contained in a crude 5-aminolevulinic acid solution by a cation exchange resin and its subsequent desorption with an aqueous solution containing ammonium ion, a high purity 5-aminolevulinic acid aqueous solution is obtained using a change in electric conductivity or pH of the desorption liquid as the index, and chloride ion is added to the aqueous solution which is then mixed with an organic solvent.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: April 3, 2012
    Assignee: Cosmo Oil Co., Ltd.
    Inventors: Hideki Okada, Tohru Tanaka, Takeshi Nomura
  • HOP ALPHA ACID OR HOP OIL CONTENT ENHANCER
    Publication number: 20110244110
    Abstract: A hop alpha acid or hop oil content enhancer, which contains 5-aminolevulinic acid, or a derivative thereof represented by the following formula (1), or a salt thereof as an active ingredient: R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
    Type: Application
    Filed: June 9, 2011
    Publication date: October 6, 2011
    Applicant: COSMO OIL CO., LTD.
    Inventors: Tohru Tanaka, Satofumi Kawata
  • PROPHYLACTIC/AMELIORATING AGENT FOR ADULT DISEASES COMPRISING 5-AMINOLEVULINIC ACID, DERIVATIVE OF 5-AMINOLEVULINIC ACID, OR SALT OF 5-AMINOLEVULINIC ACID OR THE DERIVATIVE OR 5-AMINOLEVULINIC ACID AS ACTIVE INGREDIENT
    Publication number: 20110196033
    Abstract: It is to provide a pharmaceutical composition which is different from an existing therapeutic agent of an adult disease, of a biochemical reaction-inhibiting type, and which action mechanism is to improve the basal metabolism, wherein the composition has no side effects, and does not generate drug resistance against adult disease; and a method for preventing/treating an adult disease by using the same.
    Type: Application
    Filed: October 27, 2009
    Publication date: August 11, 2011
    Applicant: SBI ALAPROMO CO., LTD.
    Inventor: Tohru Tanaka
  • THERAPEUTIC AGENT FOR MALE STERILITY
    Publication number: 20110065787
    Abstract: The present invention is intended to provide an agent for treating male infertility which is highly effective to male infertility, and having few side effects. To achieve the object, an agent for treating male infertility comprising ?-amino levulinic acid shown by general formula (1), its derivative or salt thereof: R2R1NCH2COCH2CH2COR3??(1) [wherein R1 and R2 independently represent a hydrogen atom, alkyl group, acyl group, alkoxycarbonyl group, aryl group, or aralkyl group; R3 represents a hydroxy group, alkoxy group, acyloxy group, alkoxycarbonyloxy group, aryloxy group, aralkyloxy group or amino group] can be used.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 17, 2011
    Inventors: Setsuko Miyanari, Masumi Takahashi, Masahiro Ishizuka, Tohru Tanaka
  • POLYPHENOL-CONTENT-INCREASING AGENT FOR PLANT
    Publication number: 20100173780
    Abstract: To provide a polyphenol-content-increasing agent which increases the content of polyphenol in a plant. A polyphenol-content-increasing agent for plant, containing, as an active ingredient, a 5-aminolevulinic acid or a derivative thereof represented by the following formula (1): (Chem 1) R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group which may have a substituent, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group, or a salt thereof.
    Type: Application
    Filed: July 18, 2007
    Publication date: July 8, 2010
    Applicant: COSMO OIL CO., LTD.
    Inventors: Masao Kondo, Naomi Aiba, Setsuko Miyanari, Masahiro Ishizuka, Tohru Tanaka
  • THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES
    Publication number: 20100120916
    Abstract: To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ?-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
    Type: Application
    Filed: March 27, 2008
    Publication date: May 13, 2010
    Applicant: SBI ALAPROMO CO., LTD.
    Inventors: Toshihiko Kuroiwa, Yoshinaga Kajimoto, Takahiro Masubuchi, Masahiro Ishizuka, Tohru Tanaka
  • HOP ALPHA ACID OR HOP OIL CONTENT ENHANCER
    Publication number: 20100105948
    Abstract: To provide a hop alpha acid or hop oil content enhancer, which increases the content of a hop alpha acid or a hop oil. A hop alpha acid or hop oil content enhancer, which comprises 5-aminolevulinic acid, or a derivative thereof represented by the following formula (1), or a salt thereof as an active ingredient: R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
    Type: Application
    Filed: January 30, 2008
    Publication date: April 29, 2010
    Applicant: COSMO OIL CO., LTD.
    Inventors: Tohru Tanaka, Satofumi Kawata
  • Ozone gas sensing element, detection apparatus, and measurement method
    Patent number: 7662636
    Abstract: A sensing element in which a dye that changes in the light absorption characteristic of the visible region upon reaction with ozone gas is deposited in the pores of a porous material is prepared. A change in dye before and after exposing the sensing element to a measurement environment for a predetermined time is measured. The ozone gas amount in measurement target air is measured on the basis of the change in dye.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: February 16, 2010
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Yasuko Maruo, Shigeo Ogawa, Seizou Sakata, Tohru Tanaka
  • AGENT FOR IMPROVING ALKALI RESISTANCE OF PLANT AND METHOD FOR IMPROVING ALKALI RESISTANCE OF PLANT
    Publication number: 20100035754
    Abstract: The present invention is directed to an agent for improving alkali tolerance of a plant and to a method for improving alkali tolerance of a plant through application of the agent to the plant. The agent for improving alkali tolerance of a plant is characterized by containing 5-aminolevulinic acid, a derivative thereof, or a salt of either of these and an iron compound. The method for improving alkali tolerance of plant is characterized by including treatment with the agent.
    Type: Application
    Filed: March 28, 2008
    Publication date: February 11, 2010
    Applicant: COSMO OIL CO., LTD
    Inventors: Keitaro Watanabe, Toshihiro Kobori, Tohru Tanaka, Kazuya Iwai
  • Ozone gas measurement apparatus
    Patent number: 7615192
    Abstract: A sensing element in which a dye that changes in the light absorption characteristic of the visible region upon reaction with ozone gas is deposited in the pores of a porous material is prepared. A change in dye before and after exposing the sensing element to a measurement environment for a predetermined time is measured. The ozone gas amount in measurement target air is measured on the basis of the change in dye.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: November 10, 2009
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Yasuko Maruo, Shigeo Ogawa, Seizou Sakata, Tohru Tanaka
  • METHOD FOR PRODUCING 5-AMINOLEVULINIC ACID HYDROCHLORIDE
    Publication number: 20090036709
    Abstract: A method for producing crystals of 5-aminolevulinic acid hydrochloride wherein, in carrying out adsorption of 5-aminolevulinic acid contained in a crude 5-aminolevulinic acid solution by a cation exchange resin and its subsequent desorption with an aqueous solution containing ammonium ion, a high purity 5-aminolevulinic acid aqueous solution is obtained using a change in electric conductivity or pH of the desorption liquid as the index, and chloride ion is added to the aqueous solution which is then mixed with an organic solvent.
    Type: Application
    Filed: September 5, 2006
    Publication date: February 5, 2009
    Applicant: COSMO OIL CO., LTD.
    Inventors: Hideki Okada, Tohru Tanaka, Takeshi Nomura
  • Valve, exhaust gas recirculation control valve and valve assembling method
    Patent number: 7429028
    Abstract: A valve has a housing, a shaft with a valve disc, and a sliding shaft support portion along which the shaft slides, wherein the sliding shaft support portion is provided with a seal member movable and deformable in a certain range.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: September 30, 2008
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Tohru Tanaka, Shinichi Kawasaki, Sotsuo Miyoshi, Toshihiko Miyake
  • Ozone gas sensing element, detection apparatus, and measurement method
    Publication number: 20080166815
    Abstract: A sensing element in which a dye that changes in the light absorption characteristic of the visible region upon reaction with ozone gas is deposited in the pores of a porous material is prepared. A change in dye before and after exposing the sensing element to a measurement environment for a predetermined time is measured. The ozone gas amount in measurement target air is measured on the basis of the change in dye.
    Type: Application
    Filed: March 13, 2008
    Publication date: July 10, 2008
    Inventors: Yasuko Maruo, Shigeo Ogawa, Seizou Sakata, Tohru Tanaka
  • Ozone gas sensing element, detection apparatus, and measurement method
    Publication number: 20080166267
    Abstract: A sensing element in which a dye that changes in the light absorption characteristic of the visible region upon reaction with ozone gas is deposited in the pores of a porous material is prepared. A change in dye before and after exposing the sensing element to a measurement environment for a predetermined time is measured. The ozone gas amount in measurement target air is measured on the basis of the change in dye.
    Type: Application
    Filed: March 13, 2008
    Publication date: July 10, 2008
    Inventors: Yasuko Maruo, Shigeo Ogawa, Seizou Sakata, Tohru Tanaka
  • Diagnostic Agent for Tumor
    Publication number: 20080108701
    Abstract: According to the present invention, a tumor diagnostic agent which carries out early stage detection, monitoring of therapeutic effect and prognostic diagnosis of all tumors The tumor diagnostic agent of the present invention is a tumor diagnostic agent comprising ?-aminolevulinic acid represented by formula (I), a derivative thereof and a salt thereof: R2R1NCH2COCH2CH2COR3 ??(I) wherein R1 and R2 each independently represents hydrogen, alkyl, acyl, alkoxycarbonyl, aryl or aralkyl; and R3 represents hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, aryloxy, aralkyloxy or amino, which is used for diagnoses by measuring porphyrins in a sample collected from the inside or outside of the body after its administration.
    Type: Application
    Filed: September 22, 2005
    Publication date: May 8, 2008
    Applicant: Cosmo Oil Co., Ltd
    Inventors: Ichiro Okura, Toshiaki Kamachi, Shunichiro Ogura, Masahiro Ishizuka, Tohru Tanaka