Abstract: Apparatus and method of managing genomic sequencing data. In an embodiment, a data management controller is communicatively coupled to an external data repository over a communication network. The data management controller is configured to detect a first event triggering initial analysis on raw sequence data encoded in a standard file format and stored in the external data repository. The data management controller is configured to launch one or more analysis tools to perform the initial analysis on the raw sequence data stored in the external data repository, and to output initial analysis results. The data management controller is configured to determine whether the initial analysis results pass quality control, and control electronic storage of the raw sequence data when the initial analysis results pass quality control by storing the raw sequence data in archive storage, and deleting the raw sequence data from the external data repository.

Abstract: A system and method which compensates for phase mixer circuit non-linearities within a clock and data recovery (CDR) system during active operation. The CDR system includes compensation circuitry and phase accumulation circuitry. The compensation circuitry generates a first compensation signal based on a first compensation value. The phase accumulation circuitry receives the first compensation signal and a phase accumulator input update signal. The phase accumulation circuitry combines the first compensation signal with the phase accumulator input update signal to compensate for a first non-linearity within phase mixer (PMI) circuitry.

Abstract: A storage bin assembly includes a fixed bin portion, an articulating bin portion, and an articulation system. The fixed bin portion is configured to be mounted to an aircraft, and has a cavity configured for storage of luggage. The articulating bin portion is coupled to the fixed bin portion, and includes a shelf configured for supporting luggage. The articulation system movably couples the articulating bin portion to the fixed bin portion. The articulating bin portion is movable from a first position in which the articulating bin portion is proximate to the fixed bin portion to a second position at which the articulating bin portion is separated from the fixed bin portion and lower than the fixed bin portion.

Abstract: A storage bin assembly includes a fixed bin portion, an articulating bin portion, and an articulation system. The fixed bin portion is configured to be mounted to an aircraft, and has a cavity configured for storage of luggage. The articulating bin portion is coupled to the fixed bin portion, and includes a shelf configured for supporting luggage. The articulation system movably couples the articulating bin portion to the fixed bin portion. The articulating bin portion is movable from a first position in which the articulating bin portion is proximate to the fixed bin portion to a second position at which the articulating bin portion is separated from the fixed bin portion and lower than the fixed bin portion.

Abstract: The invention relates to a computer implemented process for matching a paint to the visual appearance properties of a painted substrate surface comprising the steps of a) selecting a potentially matching first candidate paint based on a first paint recipe comprising one or more color and/or effect imparting toners, b) applying the first candidate paint to a test panel to obtain a first painted test panel c) visually comparing the appearance properties of the painted substrate surface and the first painted test panel under more than one viewing angle, wherein the visual comparison comprises c1) selecting a visual appearance category wherein the appearance of the painted test panel most prominently deviates from the painted substrate, wherein the categories are selected from a number of pre-defined visual appearance categories displayed on an output device of a computer, c2) inputting the selected visual appearance category in an input device of the computer, c3) visually determining the visual appearance diffe

Abstract: Synthesis of the novel compound 3 (3-(5-substituted Oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester) to make Pyrroloquinoline quinone (PQQ) and using it for pharmaceutical purposes is described. More specifically, this disclosure relates to synthesizing the PQQ in an efficient method by using a novel intermediate Formula 1 resulting in a shorter process and higher yield of PQQ. A unique process to make sodium compound of PQQ using either sodium hydroxide and/or sodium carbonate is also shown.

Abstract: A computing device having an optimized file system and methods for use therein. File system optimizations include sector-aligned writes, anchored cluster searches, anchored index searches, companion caches dedicated to particular file management data types and predictive cache updates, all of which expedite processing on the computing device. The file system optimizations are especially advantageous for data collection systems where an embedded device is tasked with logging to a target memory data received in a continuous data stream and where none of the streamed data is deleted until after the target memory has been offloaded to another device.

Abstract: Automatic recovery from loss of a security token on an embedded device is achieved by having a service provider (SP) server send to a device server a backup copy of the security token in conjunction with sending to an embedded device a primary copy of the security token, and retrieving from the device server and sending to the embedded device the backup copy of the security token upon detecting that the primary copy of the security token has been lost. The method and system obviate the need for a user to have to re-input on the embedded device a credential that is represented by the security token in the event the primary copy of the security token is erased from the embedded device or otherwise becomes inaccessible to the embedded device.

Abstract: A computing device having an optimized file system and methods for use therein. File system optimizations include sector-aligned writes, anchored cluster searches, anchored index searches, companion caches dedicated to particular file management data types and predictive cache updates, all of which expedite processing on the computing device. The file system optimizations are especially advantageous for data collection systems where an embedded device is tasked with logging to a target memory data received in a continuous data stream and where none of the streamed data is deleted until after the target memory has been offloaded to another device.

Abstract: Anatabine citrate and formulations containing anatabine citrate are useful for promoting health and well-being.

Abstract: Anatabine is obtained by reacting benzophenoneimine with 3-aminomethyl pyridine to form benzylhydrylidene-pyridin-3-yl-methyl-amine. The benzylhydrylidene-pyridin-3-yl-methyl-amine is treated with a non-nucleophilic base and a dielectrophile, such as cis-1,4-dichloro-2-butene, followed by acidification, then basification, to provide anatabine. The resulting anatabine is substantially free from contaminants and displays good stability. In an alternative embodiment, the benzylhydrylidene-pyridin-3-yl-methyl-amine may be used in the synthesis of other alkaloids such as anabasine, nornicotine, N-methylanabasine, and anabaseine.

Abstract: Anatabine is obtained by reacting benzophenoneimine with 3-aminomethyl pyridine to form benzylhydrylidene-pyridin-3-yl-methyl-amine. The benzylhydrylidene-pyridin-3-yl-methyl-amine is treated with a non-nucleophilic base and a dielectrophile, such as cis-1,4-dichloro-2-butene, followed by acidification, then basification, to provide anatabine. The resulting anatabine is substantially free from contaminants and displays good stability. In an alternative embodiment, the benzylhydrylidene-pyridin-3-yl-methyl-amine may be used in the synthesis of other alkaloids such as anabasine, nornicotine, N-methylanabasine, and anabaseine.

Abstract: With a growing number of personal and shared devices that may be connected to the Internet, the number of devices on which a person may receive a message increases. Privacy in message delivery may become an issue when a message may be received on a shared device, for example, a television. Aspects of the present invention relate to systems and methods for displaying message alerts on shared and private devices according to user preferences.

Abstract: The present invention relates to a novel process for the preparation of the HMG-CoA reductase inhibitor, fluvastatin, more specifically to a process for the preparation of amorphous form of fluvastatin sodium.

Abstract: Anatabine is obtained by reacting benzophenoneimine with 3-aminomethyl pyridine to form benzylhydrylidene-pyridin-3-yl-methyl-amine. The benzylhydrylidene-pyridin-3-yl-methyl-amine is treated with a non-nucleophilic base and a dielectrophile, such as cis-1,4-dichloro-2-butene, followed by acidification, then basification, to provide anatabine. The resulting anatabine is substantially free from contaminants and displays good stability. In an alternative embodiment, the benzylhydrylidene-pyridin-3-yl-methyl-amine may be used in the synthesis of other alkaloids such as anabasine, nornicotine, N-methylanabasine, and anabaseine.

Abstract: With the growing number of, both personal and shared, devices that may be connected to the Internet, the number of possible media sources that may provide input for a message increases, as does the complexity of message preparation. Additionally, with the introduction of shared devices, such as televisions, as media sources for messages, both authentication and security issues are of fundamental importance. Aspects the present invention are related to systems and methods for combining media inputs at an external, central server for messaging.

Abstract: Crystalline and amorphous polymorphic forms of Atorvastatin magnesium and processes for their preparation are claimed.

Abstract: Aspects of the present invention are related to systems and methods for providing and managing browser widgets in systems with limited user interface capabilities or computational power.

Abstract: A system for coding images, and more particularly, to a system for compressing images to a reduced number of bits by employing a Discrete Cosine Transform (DCT) in combination with a visual model.

Abstract: A novel process of the preparation of amorphous atorvastatin calcium starting from a compound of Formula (II).