Abstract: A zoom lens ZL installed in an electronic still camera 1 includes a first lens group G1 having positive refractive power disposed to the most object side, a second lens group G2 disposed to an image side of the first lens group G1, and a Gn lens group having positive refractive power disposed to the most image side. Upon zooming, the first lens group G1 and the Gn lens group are fixed. Upon focusing, at least one lens group disposed between the second lens group G2 and the Gn lens group are moved as a focusing lens group Gf. With this lens configuration, it becomes possible to provide a zoom lens having an optical property capable of coping with a vibration reduction, and an optical apparatus equipped therewith, and a method for manufacturing the zoom lens.

Abstract: Providing a zoom lens system having a vibration reduction function capable of performing quick focusing with excellent optical performance even upon vibration reduction. The system including, in order from an object, a first lens group G1 having positive refractive power, a second lens group G2 having negative refractive power, a third lens group G3 having positive refractive power, and a fourth lens group G4 having positive refractive power. Upon zooming from a wide-angle end state to a telephoto end state, a distance between the first lens group G1 and the second lens group G2 varies, and a distance between the second lens group G2 and the third lens group G3 varies. The third lens group G3 carries out focusing from an infinity object to a close object. At least a portion of the fourth lens group G4 moves in a direction perpendicular to the optical axis.

Abstract: A work machine to which a cassette gas cylinder is detachably attached is disclosed. The cassette gas cylinder is accommodated inside a gas cylinder case. The gas cylinder case for accommodating the cassette gas cylinder is detachably attached to the work machine so that the gas cylinder case wherein the cassette gas cylinder is accommodated can be transported together with the cylinder.

Abstract: Numerous disease states, such as human allergic, autoimmune, and autoimmune diseases, and cancer, may be treated by targeting OX40/OX40L. OX40L inhibits the generation of Tr1 cells from naïve and memory CD4+ T cells. This unique function of OX40L is not shared by two other costimulatory TNF-family members, GITR-ligand and 4-1BB-ligand. It has been shown that signaling the OX40-receptor on human T cells by antibodies, small molecules, or the OX40L modulates the generation and function of IL-10 producing Foxp3+ Treg immunosuppressive T cells and blocks Foxp3+ Treg function. Further, provided are high throughput methods for identifying compounds that can inhibit the immunosuppressive function of IL-10 producing Tr1 cells.

Abstract: A work vehicle includes an engine driven by gas fuel sealed inside a cassette gas cylinder. The cassette gas cylinder is installed in a cylinder mount. The cylinder mount comprises a mouthpiece support for supporting a mouthpiece of the cassette gas cylinder, and a shutter member swingable about a support shaft provided to the cylinder mount, for opening and closing an opening of the mouthpiece support from above the mouthpiece support.

Abstract: A walking-type working machine in which a gas-container housing section (cassette-type gas container) and a carry handle are mounted to a handle post. The walking-type working machine (10) is provided with a cassette-type gas container (21) mounted to a handle post (16), which rises upward and rearward from a rear section (11a) of a working machine body (11), so as to be oriented in the longitudinal direction of the handle post. A gas engine (12) is driven by fuel in the cassette-type gas container (21). The walking-type working machine is provided with a carry handle (22) for carrying the machine. The carry handle (22) is mounted to the handle post and is formed so as to surround the cassette-type gas container. The carry handle has a grip (45).

Abstract: Providing a zoom lens system having excellent optical performance, an optical apparatus, and a method for zooming the zoom lens system. The zoom lens system includes, in order from an object, a first lens group G1 having negative refractive power, a second lens group G2 having positive refractive power, and a third lens group G3 having negative refractive power. Upon zooming from a wide-angle end state W to a telephoto end state T, each distance between adjacent lens groups is varied. The first lens group G1 includes, in order from the object, a front group G1a, and a rear group G1b having negative refractive power. Focusing on the object is carried out by moving the rear group G1b along the optical axis.

Abstract: An optical system includes, in order from an object side, a first lens group having positive refractive power, a second lens group having negative refractive power, and a third lens group having positive refractive power. The second lens group is moved upon carrying out focusing from an infinitely distant object to a close object, at least a portion of the third lens group is moved in a direction including a component perpendicular to an optical axis, and given conditional expressions is satisfied. Accordingly, an optical system excellently suppressing variations in aberrations generated upon vibration reduction, an optical apparatus equipped therewith, and a method for manufacturing the optical system are provided.

Abstract: A small-sized tiller includes a stand unit configured to solely support the tiller in a self-standing state. The stand unit has a pole portion removably mountable to a resistance-bar attachment portion of the body frame when a resistance bar has been removed from the resistance-bar attachment portion.

Abstract: A zoom lens system includes, in order from an object side: a first lens group having positive refractive power; a second lens group having negative refractive power; a third lens group having positive refractive power; a fourth lens group having negative refractive power; and a fifth lens group having positive refractive power. Upon zooming from a wide-angle end state to a telephoto end state, a position of the first lens group is fixed. At least a portion of any one of the lens groups is moved in a direction including a component perpendicular to an optical axis, and a given conditional expression is satisfied, thereby providing a zoom lens system capable of excellently suppressing variation in aberrations upon zooming and upon correcting an image blur, an optical apparatus including the zoom lens system, and a method for manufacturing the zoom lens system.

Abstract: New method to control the optical transmitter is disclosed. The optical transmitter provides both of the ATC feedback loop and the APC feedback loop. When a failure occurs in the ATC feedback loop and the temperature sensor is unable to output an adequate signal any longer, the optical transmitter cuts the APC loop and operates the LD in constant conditions. The output of the monitor PD is transferred to the ATC loop to control the TEC based on the optical output of the LD.

Abstract: Providing a zoom lens system having excellent optical performance, an optical apparatus, and a method for zooming the zoom lens system. The zoom lens system includes, in order from an object, a first lens group G1 having negative refractive power, a second lens group G2 having positive refractive power, and a third lens group G3 having negative refractive power. Upon zooming from a wide-angle end state W to a telephoto end state T, each distance between adjacent lens groups is varied. The second lens group G2 includes, in order from the object, a front group G2a having positive refractive power, and a rear group G2b. Focusing on the object is carried out by moving the front group G2a along an optical axis. Given conditional expressions are satisfied.

Abstract: A variable magnification optical system ZL to be mounted on an electronic still camera 1 or the like is configured to have, in order from the object side, a first lens unit G1 having a positive refractive power, a second lens unit G2 having a negative refractive power, a third lens unit G3 having a positive refractive power, a fourth lens unit G4 having a negative refractive power, and a fifth lens unit G5 having a positive refractive power, and configured in such a manner that, in variable magnification, the first lens unit G1 is fixed, that, in focusing, the third lens unit G3 moves, and that at least a part of the fifth lens unit G5 moves so as to have a component in a substantially orthogonal direction to the optical axis.

Abstract: Operation mechanism of a working machine includes a main clutch lever pivotably provided on an operating handle, and a pivot member operable in interlocked relation to pivoting operation of the main clutch lever. The pivot member pivots about a pivot point differing in position from a pivot point of the main clutch lever. When fully pulled by pivoting operation of the main clutch lever, the cable member is located nearest to the pivot point of the pivot member, so that force reverse-pivoting the pivot member is reduced.

Abstract: A walking-type working machine in which a gas-container housing section (cassette-type gas container) and a carry handle are mounted to a handle post. The walking-type working machine (10) is provided with a cassette-type gas container (21) mounted to a handle post (16), which rises upward and rearward from a rear section (11a) of a working machine body (11), so as to be oriented in the longitudinal direction of the handle post. A gas engine (21) is driven by fuel in the cassette-type gas container (21). The walking-type working machine is provided with a carry handle (22) for carrying the machine. The carry handle (22) is mounted to the handle post and is formed so as to surround the cassette-type gas container. The carry handle has a grip (45).

Abstract: Numerous disease states, such as human allergic, autoimmune, and autoimmune diseases, and cancer, may be treated by targeting OX40/OX4OL. OX4OL inhibits the generation of Tr1 cells from naïve and memory CD4+ T cells. This unique function of OX4OL is not shared by two other costimulatory TNF-family members, GITR-ligand and 4-1BB-ligand. It has been shown that signaling the OX40-receptor on human T cells by antibodies, small molecules, or the OX4OL modulates the generation and function of IL-10 producing Foxp3+ Treg immunosuppressive T cells and blocks Foxp3+ Treg function. Further, provided are high throughput methods for identifying compounds that can inhibit the immunosuppressive function of IL-10 producing Tr1 cells.

Abstract: An engine fuel injection control apparatus includes a variable valve device that at least varies an intake valve open timing of an intake valve. A controller adjusts the variable valve device and a fuel injection timing of a fuel injection valve. The controller controls a fuel injection end timing in accordance with an overlap amount of the intake valve and an exhaust valve. The controller adjusts the fuel injection timing such that the fuel injection end timing is more advanced than the intake valve open timing and such that as an amount by which the overlap amount exceeds a prescribed overlap amount becomes larger, a time interval between the fuel injection end timing and the intake valve open timing is set to become increasingly larger, upon determining that the engine is being cold started and the overlap amount is larger than the prescribed overlap amount.

Abstract: A zoom optical system has a first lens group having a positive refracting power; a second lens group having a negative refracting power; a third lens group having a positive refracting power; a fourth lens group having a negative refracting power; and a fifth lens group having a positive refracting power, in the order from the object side. The fourth lens group is composed of a cemented lens of a negative lens and a positive lens in the order from the object side, and a condition of the following expression is satisfied: ?p>30.0, where ?p is an Abbe number of the positive lens.

Abstract: A zoom lens ZL installed in an electronic still camera 1 includes a first lens group G1 having positive refractive power disposed to the most object side, a second lens group G2 disposed to an image side of the first lens group G1, and a Gn lens group having positive refractive power disposed to the most image side. Upon zooming, the first lens group G1 and the Gn lens group are fixed. Upon focusing, at least one lens group disposed between the second lens group G2 and the Gn lens group are moved as a focusing lens group Gf. With this lens configuration, it becomes possible to provide a zoom lens having an optical property capable of coping with a vibration reduction, and an optical apparatus equipped therewith, and a method for manufacturing the zoom lens.

Abstract: Cylinder mounting mechanism is provided in a working machine for mounting thereto a cylinder case having a cassette gas cylinder accommodated therein. Mouthpiece support section is provided in the mounting mechanism for supporting a mouthpiece portion of the cassette gas cylinder in the cylinder case. Fitting recessed portion is provided in one end portion of the cylinder case and capable of receiving the mouthpiece support section, the fitting recessed portion being defined by an inner peripheral wall part of the one end portion that has a tapering wall thickness such that the surface of the wall part slants gradually outwardly toward the distal end of the fitting recessed portion.