Patents by Inventor Tomoko Matsui

Tomoko Matsui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220090041
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki-Hashizume, Yuma Kurakata, Esben Peter Friis, Jens Erik Nielsen, Roland Alexander Pache
  • Patent number: 11220679
    Abstract: The present invention relates to trehalase variants of the Myceliophthora sepedonium GH37 trehalase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: January 11, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Tomoko Matsui, Yuma Kurakata
  • Patent number: 11136568
    Abstract: The present invention relates to pullulanase variants comprising substitutions of the parent pullulanase at one or more positions corresponding to positions 393, 143, 150, 243, 244, 345, 346, 368, 370, 373, 381, 382, 385, 387, 402, 429, 430, 431, 432, 456, 486, 492, 610, 624, 631, 632, 665 and 699 of the polypeptide of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: October 5, 2021
    Assignee: Novozymes A/S
    Inventors: Tomoko Matsui, Akihiko Yamagishi
  • Publication number: 20210261988
    Abstract: Described herein are recombinant fermenting organisms having a heterologous polynucleotide encoding an alpha-amylase and/or a heterologous polynucleotide encoding a trehalase. Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant fermenting organisms.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 26, 2021
    Applicant: Novozymes A/S
    Inventors: Michael Glenn Catlett, Monica Tassone, Paul Vincent Harris, Robert Lyle Osborne, Ryoko Kataoka, Shiro Fukuyama, Tomoko Matsui
  • Publication number: 20210139876
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben P. Friis, Jens E. Nielsen, Roland Alexander Pache
  • Publication number: 20210087543
    Abstract: The present invention relates to trehalase variants of the Myceliophthora sepedonium GH37 trehalase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: August 6, 2018
    Publication date: March 25, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Tomoko Matsui, Yuma Kurakata
  • Patent number: 10947567
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: March 16, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Randy Deinhammer, Suzanne Clark, Mauricio Quiros, John Matthews, Anne Glud Hjulmand, Chee Leong Soong, Tomoko Matsui, Shinobu Takagi
  • Patent number: 10941422
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: March 9, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Randy Deinhammer, Suzanne Clark, Mauricio Quiros, John Matthews, Anne Glud Hjulmand, Chee Leong Soong, Tomoko Matsui, Shinobu Takagi
  • Patent number: 10927361
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: February 23, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben P. Friis, Jens E. Nielsen, Roland Alexander Pache
  • Publication number: 20210040510
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 11, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Randy Deinhammer, Suzanne Clark, Mauricio Quiros, John Matthews, Anne Glud Hjulmand, Chee Leong Soong, Tomoko Matsui, Shinobu Takagi
  • Publication number: 20210017546
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Application
    Filed: September 29, 2020
    Publication date: January 21, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Randy Deinhammer, Suzanne Clark, Mauricio Quiros, John Matthews, Anne Glud Hjulmand, Chee Leong Soong, Tomoko Matsui, Shinobu Takagi
  • Publication number: 20200248157
    Abstract: The present invention relates to pullulanase variants comprising substitutions of the parent pullulanase at one or more positions corresponding to positions 393, 143, 150, 243, 244, 345, 346, 368, 370, 373, 381, 382, 385, 387, 402, 429, 430, 431, 432, 456, 486, 492, 610, 624, 631, 632, 665 and 699 of the polypeptide of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 1, 2020
    Publication date: August 6, 2020
    Applicant: Novozymes A/S
    Inventors: Tomoko Matsui, Akihiko YAMAGISHI
  • Publication number: 20200199559
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein an alpha-amylase, a thermostable protease, and optionally a carbohydrate-source generating enzyme and/or pullulanase, are present and/or added during liquefaction. The invention also relates to compositions suitable for use in a process of the invention.
    Type: Application
    Filed: March 6, 2020
    Publication date: June 25, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Randall Deinhammer, Joyce Craig, Tomoko Matsui, Shinobu Takagi, Suzanne Clark, John Matthews, Anne Glud Hjulmand, Chee-Leong Soong
  • Publication number: 20200165591
    Abstract: Improved processes for producing ethanol from starch-containing materials by the combined use of at least one endoprotease and at least one exo-protease in an SSF process are disclosed. More particularly the exo-protease should make up at least 5% (w/w) of the protease mixture.
    Type: Application
    Filed: March 1, 2017
    Publication date: May 28, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Chee-Leong Soong, Bernardo Vidal Jr., Shiro Fukuyama, Tomoko Matsui, Keiichi Ayabe, Louis Patrick Lessard, Nathaniel E. Kreel, Kenneth Jensen, Ming Li, Wei Peng, Lan Tang, Xinyan Guo
  • Publication number: 20200140495
    Abstract: The present invention relates to polypeptides having trehalase activity, particularly derived from Talaromyces. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides for the production of ethanol.
    Type: Application
    Filed: June 26, 2018
    Publication date: May 7, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Marc Dominique Morant, Tomoko Matsui, Kirk Matthew Schnorr, Shiro Fukuyama, Noriko Tsutsumi, Zhengfang Kang
  • Patent number: 10640755
    Abstract: The present invention relates to pullulanase variants comprising substitutions of the parent pullulanase at one or more positions corresponding to positions 393, 143, 150, 243, 244, 345, 346, 368, 370, 373, 381, 382, 385, 387, 402, 429, 430, 431, 432, 456, 486, 492, 610, 624, 631, 632, 665 and 699 of the polypeptide of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 5, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Tomoko Matsui, Akihiko Yamagishi
  • Publication number: 20190352629
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: July 14, 2017
    Publication date: November 21, 2019
    Applicant: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben Peter Friis, Jens Erik Nielsen, Roland Alexander Pache
  • Patent number: 10472617
    Abstract: The present invention relates to asparaginase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. The invention further relates to a process of producing a fermentation product, comprising: liquefying a starch-containing material to dextrins with an alpha-amylase in the presence of an asparaginase of the invention; saccharifying the dextrins to a sugar with a glucoamylase; and fermenting the sugar using a fermenting organism.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: November 12, 2019
    Assignee: Novozymes A/S
    Inventors: Tomoko Matsui, Aki Tomiki, Allan Svendsen, Hanne Vang Hendriksen, Mary Ann Stringer, Keiichi Ayabe
  • Publication number: 20190271011
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Application
    Filed: May 9, 2019
    Publication date: September 5, 2019
    Applicant: NOVOZYMES A/S
    Inventors: Randy Deinhammer, Suzanne Clark, Mauricio Quiros, John Matthews, Anne Glud Hjulmand, Chee Leong Soong, Tomoko Matsui, Shinobu Takagi
  • Patent number: 10227613
    Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein an alpha-amylase and optionally a thermostable protease, pullulanase and/or glucoamylase are present and/or added during liquefaction, wherein a cellulolytic composition is present and/or added during fermentation or simultaneous saccharification and fermentation. The invention also relates to a composition suitable for use in a process of the invention.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: March 12, 2019
    Assignee: Novozymes A/S
    Inventors: Randall Deinhammer, Joyce Craig, Tomoko Matsui, Shinobu Takagi, Suzanne Clark, John Matthews, Anne Glud Hjulmand, Chee-Leong Soong, Zhengfang Kang