Abstract: Although compounds for treating or ameliorating malignant diseases have been proposed, patients had to endure a large burden since many of such compounds could not be orally ingested. Mangiferin has an effect of ameliorating malignant diseases through oral ingestion. However, such effect is minor and realistically it was not easy to ingest mangiferin. Further, in order to develop more effective pharmaceutical agents and the like for treating malignant diseases, it has been considered constantly necessary to obtain new or improved forms of an existing medical agent for inhibiting kinases such as NIK. Compounds represented by formula (1), formula (2), formula (3), formula (4), formula (5), formula (6), formula (7), formula (8), formula (9), formula (10), formula (11), and formula (12) have an effect of ameliorating malignant diseases through oral ingestion, and can exhibit said effect with an amount less than that for mangiferin.

Abstract: [Problem] COVID-19 caused by coronavirus SARS-CoV-2, cytokine release syndrome, cytokine release syndrome with CAR (chimeric antigen receptor)-T therapy, sepsis, systemic inflammatory response syndrome, hemophagocytic syndrome, macrophage activation syndrome, influenza, GVHD, systemic vasculitis, Kawasaki disease, Takayasu arteritis, and other diseases, if severe, can cause acute respiratory distress syndrome, disseminated intravascular coagulation syndrome, acute circulatory insufficiency, multi-organ failure, and other symptoms which are one of the causes of death. [Solution to Problem] Compounds represented by formulas (1) to (4) are effective when taken orally and can be expressed in smaller amounts than mangiferin.

Abstract: There are no drugs or food medicines that can prevent or ameliorate, among side effects caused by drugs, particularly peripheral neuropathy that is caused by anticancer drugs such as oxaliplatin. An agent for preventing or ameliorating peripheral neuropathy including at least one selected from xylitol, L-talitol, and D-threitol as an active ingredient can ameliorate tingling limbs, limb pain, decreased deep tendon reflexes, muscle weakness, allodynia, hyperalgesia, hand fine motor skill disability, gait disturbance, stumbling, falling, flexion impairment (difficulty or inability to sit on one's knees, cross-legged, sideways, in a chair, etc.), limb paralysis, or the like, induced by drugs such as anticancer drugs or diabetes.

Abstract: A mirror support mechanism includes three first supporting members and three second supporting members. Each first supporting member includes a mirror supporting portion that is in contact with and support a corresponding one of three supported surfaces provided on the supported portion with rotational symmetry of 120 degrees around an optical axis, and two first beam portions connected to both sides of the mirror supporting portion. Each second supporting member includes a supporting portion to which ends of two first beam portions adjacent to each other are connected, the ends being not connected to the mirror supporting portion, and two second beam portions connected to both sides of the supporting portion, an end of the second beam portion not connected to the supporting portion being supported by a structure member provided on the rear side of the reflecting mirror.

Abstract: A method for operating an air conditioner installed in a vehicle is provided. The method includes a step of operating the air conditioner according to an operation instruction for the air conditioner when the operation instruction is received from a mobile terminal of an operator of the vehicle, and a step of displaying a notification related to an operation of the air conditioner on a screen of the mobile terminal while the air conditioner is operated according to the operation instruction, the step being a step in which the notification related to the operation of the air conditioner is continuously displayed on the screen without being deleted by a predetermined operation of the mobile terminal by the operator when the mobile terminal is located outside the vehicle.

Abstract: A system is configured to, if an unmanned autonomous vehicle that runs on electric power, for example, a robotaxi, needs to be charged, make a request of a person around a charging station, for example, a driver of an electrified vehicle being charged, to do work for charging the robotaxi with a smartphone. At this time, the system may make a request to do work for charging the robotaxi in return for giving an incentive.

Abstract: A method for managing a car rental service for renting a vehicle in response to a rental request from a user is provided. The method includes the steps of: acquiring image data of at least one of the surroundings and the interior of the vehicle acquired using a camera mounted on the vehicle; and processing the at least one image data acquired during the lending of the vehicle to the user in a reproducible manner at the terminal of the owner when a request for confirmation of the at least one image data is received from the terminal of the owner of the vehicle after the lending of the vehicle to the user.

Abstract: The vehicle management server manages a vehicle rented as a robot taxi from an owner to a user. The vehicle management server transmits the vehicle position information to a communication terminal of the owner when the vehicle is in operation as a robot taxi. The vehicle position information is a distance from the current position of the owner to the vehicle, or an area where the vehicle is currently located.

Abstract: The autonomous driving vehicle of the present disclosure is equipped with a solar cell and a battery capable of charging electric power generated by the solar cell. The autonomous driving vehicle of the present disclosure searches for a solar power generation point in which the charge power amount of the battery increases more than the current location, and moves to the solar power generation point in the autonomous driving.

Abstract: An imaging device (100) includes: an imaging element (112) including a pixel capable of detecting a depth; an image processing unit (120) configured to detect a depth using a signal obtained from the pixel and perform processing based on the depth; and a correction data generation unit (130) configured to generate, based on the signal, a correction map for correcting image height dependency of the depth in the image processing unit (120).

Abstract: A cross member structure of a vehicle body includes a floor panel (2) provided below a vehicle interior in the vehicle body (10); side sills (3) that are provided on both sides of the floor panel (2) in a vehicle width direction and extend in a front-rear direction of the vehicle body (10); a cross member (4) that extends in the vehicle width direction and connects the side sills (3) to each other; and a reinforcement (5) that is provided between the cross member (4) and the floor panel (2) and extends in the vehicle width direction, wherein the cross member (4) includes a curved portion (41) that is curved to at least one side in a vertical direction of the vehicle body (10) outward from the reinforcement (5) in the vehicle width direction.

Abstract: No drug has been available for treating a peripheral sensory neuropathy caused as a side effect by a drug, in particular, by an anticancer drug such as oxaliplatin. A composition for ameliorating peripheral sensory neuropathy, which is characterized by including a Lentinus edodes mycelium extract, ameliorates symptoms induced by the drug such as the anticancer drug, including numbness of extremities, a pain in extremities, a reduction in deep tendon reflection, a reduction in muscle force, allodynia, hyperalgesia, impaired finger fine movement, impaired walking, stumbling, falling, impaired flexion (being difficult or impossible to sit on one's heels, sit cross-legged, sit with one's legs out to one side, sit on a chair, or the like), or paralysis of extremities.

Abstract: A control apparatus includes a processor that determines whether an ice generation condition is satisfied on the basis of at least one or both of a state of a heat source of a vehicle and an outside air temperature after an operation stop of a drive source of the vehicle. If the ice generation condition is satisfied, the processor repeats an ice-crushing operation at a predetermined time interval in a predetermine ice-crushing time period by turning on and thereafter turning off the relay. The predetermined ice-crushing time period is determined on the basis of a temperature difference between a temperature of the fixed contact or the movable contact of the relay and a temperature of an internal atmosphere inside the relay. The predetermined time interval is a time period in which the ice on the fixed contact and the movable contact of the relay grows to a predetermined size.

Abstract: A sensor mounting structure for a vehicle, includes: first mounting members extending in a vehicle front-and-rear direction, being separated by a spacing in a vehicle width direction, and being mountable at arbitrary positions of a roof of the vehicle; and second mounting members extending in the vehicle width direction, being separated by a spacing in the vehicle front-and-rear direction, and being configured to span between arbitrary positions of the first mounting members, the second mounting members and the first mounting members retaining a sensor support member.

Abstract: According to one embodiment, a thermionic power generation element includes a cathode, an anode, and an insulating member. The cathode includes an electrically-conductive material. The anode includes an electrically-conductive material. The insulating member is located between the cathode and the anode. The cathode and the anode have a gap between the cathode and the anode. A first through-hole is provided in the anode. The first through-hole extends through the anode in a first direction and communicates with the gap. The first direction is from the cathode toward the anode.

Abstract: A vehicle rear structure includes side reinforcing members and a support member. The side reinforcing members reinforce rear damper housings. The support member includes an upper rod member, a lower rod member, and a posture maintaining member. The upper rod member lies across the side reinforcing members. The lower rod member is disposed below the upper rod member. The posture maintaining member is disposed between the upper rod member and the lower rod member and is joined to the upper rod member and the lower rod member at a plurality of places in a vehicle width direction.

Abstract: An imaging device (100) includes: an imaging element (112) including a pixel capable of detecting a depth; an image processing unit (120) configured to detect a depth using a signal obtained from the pixel and perform processing based on the depth; and a correction data generation unit (130) configured to generate, based on the signal, a correction map for correcting image height dependency of the depth in the image processing unit (120).

Abstract: Provided is a solid state imaging device including: a pixel array in which pixels are disposed on a matrix; an iris authenticator that extracts iris information to be used in an iris authentication process, from image data obtained from the pixel array through photoelectric conversion; and an imaging condition controller that performs control to set an imaging condition in obtaining the image data for the iris authentication process, by using information obtained in a process of extracting the iris information.

Abstract: To achieve a configuration of controlling a light source unit having a plurality of light sources and a rangefinder (camera) by individual clocks to allow for setting the light sources at optional positions. The output light of a plurality of light sources of the light source unit is reflected from an object's surface, and a ToF sensor captures the reflected light to calculate the distance to the object. A sensor clock that controls the image capturing timing of the ToF sensor is the clock specific to the rangefinder, which is different from a light source unit clock that controls the light emission timing of the light sources of the light source unit. The rangefinder creates a difference calculation formula of a plurality of distance calculation formulas used to calculate the distance from each light source to the rangefinder to calculate the distance to the object using the created difference calculation formula.

Abstract: No drug has been available for treating a peripheral sensory neuropathy caused as a side effect by a drug, in particular, by an anticancer drug such as oxaliplatin. A composition for ameliorating peripheral sensory neuropathy, which is characterized by including a Lentinus edodes mycelium extract, ameliorates symptoms induced by the drug such as the anticancer drug, including numbness of extremities, a pain in extremities, a reduction in deep tendon reflection, a reduction in muscle force, allodynia, hyperalgesia, impaired finger fine movement, impaired walking, stumbling, falling, impaired flexion (being difficult or impossible to sit on one's heels, sit cross-legged, sit with one's legs out to one side, sit on a chair, or the like), or paralysis of extremities.