Patents by Inventor Toni-Jo Poel

Toni-Jo Poel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBACTERIAL FLUOROQUINOLONE ANALOGS
    Publication number: 20120058989
    Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, D, E, G, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: April 7, 2011
    Publication date: March 8, 2012
    Applicant: Achaogen, Inc.
    Inventors: Allan S. Wagman, Heinz E. Moser, Glenn A. McEnroe, James B. Aggen, Martin S. Linsell, Adam A. Goldblum, John H. Griffin, Lloyd J. Simons, Thomas R. Belliotti, Christina R. Harris, Toni-Jo Poel, Michael J. Melnick, Ricky D. Gaston
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Patent number: 7645781
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: January 12, 2010
    Assignee: Pfizer Inc
    Inventors: Richard C. Thomas, Toni-Jo Poel, Michael R. Barbachyn, Mikhail F. Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh, Vara Prasad Venkata Negandra Josyula
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Publication number: 20070015801
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Application
    Filed: September 21, 2006
    Publication date: January 18, 2007
    Inventors: Richard Thomas, Toni-Jo Poel, Michael Barbachyn, Mikhail Gordeev, Gary Luehr, Adam Renslo, Upinder Singh, Vara Nagendra Josyula
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Patent number: 7141588
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: November 28, 2006
    Assignee: Pfizer, Inc.
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail Fedor Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh, Vara Prasad Venkata Nagendra Josyula
  • Indolone oxazolidinones and derivatives thereof
    Patent number: 7012088
    Abstract: The present invention provides antibacterial agents of formula I described herein and intermediates for their preparation.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: March 14, 2006
    Assignee: Pharmacia & Upjohn Company
    Inventor: Toni-Jo Poel
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Patent number: 6972286
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: December 6, 2005
    Assignee: Pharmacia and Upjohn Company
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Novel imidazoles
    Publication number: 20050239857
    Abstract: Novel imidazoles are provided. The compounds are useful as HMGCo-A Reductase Inhibitor. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 27, 2005
    Inventors: Gary Bolton, Daniel Bowles, David Boyles, Walter Howard, Richard Hutchings, Robert Kennedy, William Park, Toni-Jo Poel, Yuntao Song
  • N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Patent number: 6919329
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: July 19, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail F. Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh
  • N-alkyl pyrroles as HMG-CoA reductase inhibitors
    Publication number: 20050154042
    Abstract: HMGCo-A reductase inhibitor compounds useful as hypocholesterolemic and hypolipidemic compounds are provided. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.
    Type: Application
    Filed: December 2, 2004
    Publication date: July 14, 2005
    Inventors: Larry Bratton, Xue-Min Cheng, Chitase Lee, Steven Miller, Jeffrey Pfefferkorn, Toni-Jo Poel, Roderick Sorenson, Yuntao Song, Kuai-Lin Sun, Bharat Trivedi, Paul Unangst
  • Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings
    Publication number: 20050054683
    Abstract: A process for preparing a compound of the formula I: or pharmaceutical acceptable salts thereof wherein X is —NR1—, —S(O)g—, or —O—; R1 is —H, C1-6 alkyl optionally substituted with one or more —OH, —CN, or halo, or R1 is —(CH2)h-aryl, —COR1-1, —COOR1-2, —CO—(CH2)h—COR1-1, C1-6 alkyl sulfonyl, —SO2—(CH2)h-aryl, or —(CO)i-Het; R2 is —H, C1-6 alkyl, —(CH2)h-aryl, or halo; R3 and R4 are the same or different and are —H or halo; R5 is —H, C1-12 alkyl optionally substituted with one or more halo, C3-12 cycloalkyl, C1-6 alkoxy. The compounds are useful antimicrobial agents.
    Type: Application
    Filed: March 22, 2003
    Publication date: March 10, 2005
    Inventors: Douglas Hutchinson, Michael Ennis, Robert Hoffman, Richard Thomas, Toni-Jo Poel, Michael Barbachyn, Steven Brickner, David Anderson
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20040186293
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: March 19, 2004
    Publication date: September 23, 2004
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20040176609
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: March 19, 2004
    Publication date: September 9, 2004
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Indolone oxazolidinones and derivatives thereof
    Publication number: 20040176610
    Abstract: The present invention provides antibacterial agents of formula I described herein and intermediates for their preparation.
    Type: Application
    Filed: January 22, 2004
    Publication date: September 9, 2004
    Inventor: Toni-Jo Poel
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Publication number: 20040147760
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Application
    Filed: August 22, 2003
    Publication date: July 29, 2004
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail Fedor Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh, Vara Prasad Venkata Nagendra Josyula
  • N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Publication number: 20040044052
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Application
    Filed: February 24, 2003
    Publication date: March 4, 2004
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail F. Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh
  • Oxazolidinone antibacterial agents having a thiocarbonyl funtionality
    Patent number: 6537986
    Abstract: The present invention provides compounds of Formula 1 or pharmaceutical acceptable salts thereof wherein A, G and R1 are as defined in the claims which are antibacterial agents.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: March 25, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jackson B. Hester, Jr., Eldon George Nidy, Salvatore Charles Perricone, Toni-Jo Poel
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20020133021
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: November 14, 2001
    Publication date: September 19, 2002
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Phenyloxazolidinones having a c-c bond 4-8 membered heterocyclic rings
    Patent number: 6358942
    Abstract: A compound of Formula (I): or pharmaceutical acceptable salts thereof wherein X is NR1; R1 is H, C1-6 alkyl optionally substituted with one or more OH, CN, or halo, or R1 is —(CH2)h-aryl, —COR1-1, —COOR1-2, —CO—(CH2)h—COR1-1, C1-6 alkyl sulfonyl, —SO2—(CH2)h-aryl, or —(CO)i-Het; R2 is H, C1-6 alkyl, —(CH2)h-aryl, or halo; R3 and R4 are independently H or halo; R5 is H, C1-12 alkyl optionally substituted with one or more halo, C3-12 cycloalkyl, C1-6 alkoxy; m and n taken together are 1 or 2. The compounds are useful antimicrobial agents.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: March 19, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Richard C. Thomas, Toni-Jo Poel
  • Oxazolidinone antibacterial agents having a thiocarbonyl functionality
    Publication number: 20020016323
    Abstract: The present invention provides compounds of Formula 1 1
    Type: Application
    Filed: March 30, 2001
    Publication date: February 7, 2002
    Applicant: Pharmacia & Upjohn Company
    Inventors: Jackson B. Hester, Eldon George Nidy, Salvatore Charles Perricone, Toni-Jo Poel
  • Oxazolidinone antibacterial agents having a thiocarbonyl functionality
    Publication number: 20010041728
    Abstract: The present invention provides compounds of Formula 1 1
    Type: Application
    Filed: March 30, 2001
    Publication date: November 15, 2001
    Inventors: Jackson B. Hester, Eldon George Nidy, Salvatore Charles Perricone, Toni-Jo Poel