Patents by Inventor Tonya D. Bonilla

Tonya D. Bonilla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10619189
    Abstract: A composition for reducing the inhibitory effects of contaminants on nucleic acid amplification is provided. The composition includes a plurality of zirconium oxide particles, a non-ionic surfactant, and an organic iron-chelating reagent. The organic iron-chelating reagent has a first affinity constant greater than or equal to 104.2 with respect to ferric iron and a second affinity constant less than 103.8 with respect to magnesium, wherein the first affinity constant and the second affinity constant are determined in deionized water at pH 8.45 and 20° C. Optionally, the composition includes polyvinylpyrrolidone. Optionally, the composition comprises water. The composition has a pH of about 8.45 to 8.85. Methods of using the composition to prepare a sample for nucleic acid amplification are also provided.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: April 14, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Gregory W. Sitton, Wensheng Xia, Tonya D. Bonilla
  • Publication number: 20190338335
    Abstract: An article is provided. The article comprises a nonwoven substrate having a copolymer grafted thereto, and a dried coating adhered to the substrate. The copolymer comprises interpolymerized monomer units of a quaternary ammonium-containing ligand monomer, an amide monomer, and an oxy monomer. The coating comprises a plurality of test microorganisms. Optionally, the coating further comprises a water-soluble or water-dispersible polymeric binding agent. A process challenge device comprising a body having a hollow channel with said article fixed disposed therein is also provided. Methods of using the article or the process challenge device for determining the efficacy of a disinfection process are also provided.
    Type: Application
    Filed: December 20, 2017
    Publication date: November 7, 2019
    Inventors: Assumpta A. G. Bennaars-Eiden, Tonya D. Bonilla, Jodi L. Connell, John J. Schmidt, Andrew W. Vail, Federica Sgolastra
  • Publication number: 20190255208
    Abstract: A microbial indicator device for liquid disinfection comprises a first cavity, a source of biological activity fluidically coupled to the first cavity via a portion of a first fluidic path, a filter membrane positioned in a second fluidic path for a disinfectant, and a first coupling portion fluidically coupled to the source of biologically activity via the second fluidic path. The filter membrane has a first side and a second side, wherein the first side is in fluid communication with the first fluidic path. The filter membrane has a pore size sufficient to retain at least a portion of the source of biological activity on the first side. The device further comprises a frangible container contained in the first cavity, wherein a liquid in the container is in fluid communication with the first cavity when the container is fractured.
    Type: Application
    Filed: October 12, 2017
    Publication date: August 22, 2019
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: G. MORCO BOMMARITO, TIMOTHY J. NIES, BARRY W. ROBOLE, ASSUMPTA A. G. BENNAARS-EIDEN, JODI L. CONNELL, TONYA D. BONILLA, TOMOTHY A. KOHMAN, RUTHANN R. DUDA
  • Publication number: 20180142280
    Abstract: A composition for reducing the inhibitory effects of contaminants on nucleic acid amplification is provided. The composition includes a plurality of zirconium oxide particles, a non-ionic surfactant, and an organic iron-chelating reagent. The organic iron-chelating reagent has a first affmity constant greater than or equal to 104.2 with respect to ferric iron and a second affinity constant less than 103.8 with respect to magnesium, wherein the first affmity constant and the second affinity constant are determined in deionized water at pH 8.45 and 20° C. Optionally, the composition includes polyvinylpyrrolidone. Optionally, the composition comprises water. The composition has a pH of about 8.45 to 8.85. Methods of using the composition to prepare a sample for nucleic acid amplification are also provided.
    Type: Application
    Filed: May 9, 2016
    Publication date: May 24, 2018
    Inventors: GREGORY W. SITTON, WENSHENG XIZ, TONYA D. BONILLA
  • Publication number: 20140038228
    Abstract: A method of processing a sample for analysis is disclosed. The method includes providing a first sample-transfer article with a sample disposed therein, a container (1110), a pierceable cap (1120), and a pierceable layer (1500). The method further includes operably coupling the cap (1120) and the container (1110), disposing the pierceable layer (1500) adjacent the cap (1120), urging the first sample-transfer article through the layer (1500) and the cap (1120), transferring a portion of the sample into the container (1110), and separating the layer (1500) from the cap (1120). The method further can comprise providing a second sample transfer article having a second sample delivery end and urging the second sample-transfer article through the cap. A kit comprising a container, a cap, a pierceable layer; and means for coupling the pierceable layer to the cap and/or to the container is also provided.
    Type: Application
    Filed: April 19, 2012
    Publication date: February 6, 2014
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Neil Percy, Gregory W. Sitton, Tonya D. Bonilla