Patents by Inventor Toru Fujimura

Toru Fujimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7742165
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the reflection spectrum.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: June 22, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Patent number: 7726004
    Abstract: A processing cell of automatic machining system configured in that it is easy to decide or change the number of steps and to design, and to reduce the installation cost. The control unit of the processing cell comprises an operation data storing means for storing every position necessary data for operation at each position of the processing cell installed in the machining section of the automatic machining system, and a position designating means for designating the after-installation position. The control unit reads necessary data for operation out of the operation data storing means in accordance with the position designated by the position designating means. Thus, the operation of each cell can be switched in accordance with the position, and the processing cells can be easily changed in position and adjusted in quantity.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: June 1, 2010
    Assignee: Nissin Manufacturing Co., Ltd.
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Patent number: 7439073
    Abstract: An object of the present invention is to provide a simple biochemical sensor making use of the light interference effect of an optical film which is capable of measuring binding of biochemical substances at a high throughput. In the present invention, a solution containing samples 18 is passed through the sensor having probes 17 provided on an optical film with a refractive index of not less than 1.8 and not greater than 3 on a substrate, and binding of the probes 17 and samples 18 is detected from the change of intensity of the reflected light. This makes it possible to measure binding of biochemical substances at a high throughput with high precision.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: October 21, 2008
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Juergen Pipper
  • Publication number: 20080147220
    Abstract: A processing cell of automatic machining system configured in that it is easy to decide or change the number of steps and to design, and to reduce the installation cost. The control unit of the processing cell comprises an operation data storing means for storing every position necessary data for operation at each position of the processing cell installed in the machining section of the automatic machining system, and a position designating means for designating the after-installation position. The control unit reads necessary data for operation out of the operation data storing means in accordance with the position designated by the position designating means. Thus, the operation of each cell can be switched in accordance with the position, and the processing cells can be easily changed in position and adjusted in quantity.
    Type: Application
    Filed: January 31, 2008
    Publication date: June 19, 2008
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Patent number: 7346973
    Abstract: A processing cell of automatic machining system configured in that it is easy to decide or change the number of steps and to design, and to reduce the installation cost. The control unit of the processing cell comprises an operation data storing means for storing every position necessary data for operation at each position of the processing cell installed in the machining section of the automatic machining system, and a position designating means for designating the after-installation position. The control unit reads necessary data for operation out of the operation data storing means in accordance with the position designated by the position designating means. Thus, the operation of each cell can be switched in accordance with the position, and the processing cells can be easily changed in position and adjusted in quantity.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: March 25, 2008
    Assignee: Nissin Manufacturing Co., Ltd.
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Patent number: 7311881
    Abstract: A chip having a deaerating function and requiring no bonding or welding for forming a channel, and an apparatus and method for the reaction analysis are provided. The chip contains a first substrate, a second substrate having a liquid inlet and a liquid outlet, and an intermediate member having hydro-phobicity and air permeability and forming a channel between the first and second substrates. It is thereby possible to prevent mixing of air bubbles into the channel.
    Type: Grant
    Filed: September 1, 2004
    Date of Patent: December 25, 2007
    Assignee: Hitachi, Ltd.
    Inventors: Kei Takenaka, Toru Fujimura, Yasushi Goto
  • Patent number: 7306941
    Abstract: A simple and convenient sensor and measuring apparatus utilizing the optical interference effect of an optical thin film capable of measuring the binding between biochemical substances at a high throughput and having alkali resistance. An optical thin film of silicon nitride is disposed on the first surface and the rear surface of a silicon substrate, and the thickness of the silicon nitride film is modified in a direction parallel to the film. A portion of the thin film with increased thickness is used as a sensor upon which a probe is disposed, and over which a sample-containing solution is caused to flow. The binding between the probe and biochemical sample is detected based upon the change of the intensity of reflected light.
    Type: Grant
    Filed: December 9, 2004
    Date of Patent: December 11, 2007
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Yasushi Goto
  • Publication number: 20070212259
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
    Type: Application
    Filed: January 30, 2007
    Publication date: September 13, 2007
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Publication number: 20050250198
    Abstract: A simple and convenient sensor and measuring apparatus utilizing the optical interference effect of an optical thin film capable of measuring the binding between biochemical substances at a high throughput and having alkali resistance. An optical thin film of silicon nitride is disposed on the first surface and the rear surface of a silicon substrate, and the thickness of the silicon nitride film is modified in a direction parallel to the film. A portion of the thin film with increased thickness is used as a sensor upon which a probe is disposed, and over which a sample-containing solution is caused to flow. The binding between the probe and biochemical sample is detected based upon the change of the intensity of reflected light.
    Type: Application
    Filed: December 9, 2004
    Publication date: November 10, 2005
    Inventors: Toru Fujimura, Yasushi Goto
  • Patent number: 6920678
    Abstract: This is a processing cell of an automatic machining system having a small, lightweight and simple structure, easy to determine or change the number of process, easy in design, and low in apparatus cost. A processing cell (A) has a unit structure comprising a conveying device (10) forming a part of a work conveying route (1), a fine boring machine (5a) or honing machine (5b), (5c) as a single machine tool, and a control unit for linking them mutually and controlling, and these cells are installed, being free to increase or decrease in number, in the machining section of automatic machining system such as automatic honing system.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: July 26, 2005
    Assignee: Nissin Manufacturing Co., Ltd.
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Publication number: 20050136685
    Abstract: A chip having a deaerating function and requiring no bonding or welding for forming a channel, and an apparatus and method for the reaction analysis are provided. The chip contains a first substrate, a second substrate having a liquid inlet and a liquid outlet, and an intermediate member having hydro-phobicity and air permeability and forming a channel between the first and second substrates. It is thereby possible to prevent mixing of air bubbles into the channel.
    Type: Application
    Filed: September 1, 2004
    Publication date: June 23, 2005
    Inventors: Kei Takenaka, Toru Fujimura, Yasushi Goto
  • Patent number: 6821361
    Abstract: A method and apparatus for quantitatively measuring a metal phase contained in a galvanized layer by X-ray diffractometry, and a method of producing a galvanized steel sheet by using the method and apparatus. The diffracted X-ray intensity from a metal phase contained in the galvanized layer is increased to improve measurement accuracy, thereby permitting application to on-line measurement. The diffracted X-rays from the metal phase are measured over a predetermined range on a Debye ring, or measured at a plurality of positions on the Debye ring to increase the diffracted X-ray intensity, thereby improving measurement accuracy. The X-ray beam produced by an X-ray source is compressed and made parallel and monochromatic by a multilayer film mirror to increase diffracted X-ray intensity, improving measurement accuracy. Particularly, the present invention is applied to measurement of the degree of alloying of hot-dip galvanization.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: November 23, 2004
    Assignee: JFE Steel Corporation
    Inventors: Toru Fujimura, Akira Yamamoto
  • Publication number: 20040109734
    Abstract: A processing cell of automatic machining system configured in that it is easy to decide or change the number of steps and to design, and to reduce the installation cost. The control unit of the processing cell comprises an operation data storing means for storing every position necessary data for operation at each position of the processing cell installed in the machining section of the automatic machining system, and a position designating means for designating the after-installation position. The control unit reads necessary data for operation out of the operation data storing means in accordance with the position designated by the position designating means. Thus, the operation of each cell can be switched in accordance with the position, and the processing cells can be easily changed in position and adjusted in quantity.
    Type: Application
    Filed: August 18, 2003
    Publication date: June 10, 2004
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Publication number: 20040070764
    Abstract: An object of the present invention is to provide a simple biochemical sensor making use of the light interference effect of an optical film which is capable of measuring binding of biochemical substances at a high throughput. In the present invention, a solution containing samples 18 is passed through the sensor having probes 17 provided on an optical film with a refractive index of not less than 1.8 and not greater than 3 on a substrate, and binding of the probes 17 and samples 18 is detected from the change of intensity of the reflected light. This makes it possible to measure binding of biochemical substances at a high throughput with high precision.
    Type: Application
    Filed: February 25, 2003
    Publication date: April 15, 2004
    Applicant: Hitachi, Ltd.
    Inventors: Toru Fujimura, Juergen Pipper
  • Publication number: 20030121138
    Abstract: This is a processing cell of an automatic machining system having a small, lightweight and simple structure, easy to determine or change the number of process, easy in design, and low in apparatus cost. A processing cell (A) has a unit structure comprising a conveying device (10) forming a part of a work conveying route (1), a fine boring machine (5a) or honing machine (5b), (5c) as a single machine tool, and a control unit for linking them mutually and controlling, and these cells are installed, being free to increase or decrease in number, in the machining section of automatic machining system such as automatic honing system.
    Type: Application
    Filed: November 20, 2002
    Publication date: July 3, 2003
    Inventors: Hiroyuki Ooe, Toru Fujimura, Kazuhiko Tsuji, Yasuo Tomita
  • Publication number: 20020174918
    Abstract: The present invention relates to a method and apparatus for quantitatively measuring a metal phase contained in a galvanized layer by X-ray diffractometry, and a method of producing a galvanized steel sheet by using the method and apparatus. The diffracted X-ray intensity from a metal phase contained in the galvanized layer is increased to improve measurement accuracy, thereby permitting application to on-line measurement. The diffracted X-rays from the metal phase are measured over a predetermined range on a Debye ring, or measured at a plurality of positions on the Debye ring to increase the diffracted X-ray intensity, thereby improving measurement accuracy. The X-ray beam produced by an X-ray source is compressed and made parallel and monochromatic by a multilayer film mirror to increase diffracted X-ray intensity, improving measurement accuracy. Particularly, the present invention is applied to measurement of the degree of alloying of hot-dip galvanization.
    Type: Application
    Filed: May 22, 2002
    Publication date: November 28, 2002
    Inventors: Toru Fujimura, Akira Yamamoto