Patents by Inventor Toru Sano

Toru Sano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7825375
    Abstract: A microchip 100 is employed as target board of mass spectrometry. The microchip 100 includes a substrate 120, a plurality of sample-distributing sections, provided in the substrate 120 and contains samples that serve as a target of a mass spectrometry distributed therein, and a reference material-supplying channel provided in the substrate 120 and capable of being supplied with a reference material in the mass spectrometry. The plurality of sample-distributing sections are provided in the lateral side of the fine channel 102 for distributing the reference material along the fine channel 102 for distributing the reference material.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: November 2, 2010
    Assignee: NEC Corporation
    Inventor: Toru Sano
  • Patent number: 7785533
    Abstract: A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: August 31, 2010
    Assignee: NEC Corporation
    Inventors: Machiko Fujita, Toru Sano, Kazuhiro Iida, Hisao Kawaura, Wataru Hattori, Masakazu Baba, Noriyuki Iguchi
  • Publication number: 20090266980
    Abstract: A microchip 100 is employed as target board of mass spectrometry. The microchip 100 includes a substrate 120, a plurality of sample-distributing sections, provided in the substrate 120 and contains samples that serve as a target of a mass spectrometry distributed therein, and a reference material-supplying channel provided in the substrate 120 and capable of being supplied with a reference material in the mass spectrometry. The plurality of sample-distributing sections are provided in the lateral side of the fine channel 102 for distributing the reference material along the fine channel 102 for distributing the reference material.
    Type: Application
    Filed: November 9, 2006
    Publication date: October 29, 2009
    Inventor: Toru Sano
  • Patent number: 7586091
    Abstract: After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separated in the channel. The ionized fraction is detected by a mass spectrometry unit (363) and analyzed by an analytical result analyzing unit (371). The analytical result is stored in a memory (369) while associated with position information in a driver control unit (367) and information on laser beam irradiation condition in a laser control unit (373), and the analytical result is imaged by an imaging unit (375). The imaged analytical result is displayed on a display (377).
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: September 8, 2009
    Assignee: NEC Corporation
    Inventors: Katsutoshi Takahashi, Kazuhiro Iida, Masakazu Baba, Noriyuki Iguchi, Toru Sano, Hisao Kawaura, Toshitsugu Sakamoto, Wataru Hattori, Hiroko Someya
  • Publication number: 20090070045
    Abstract: A diagnosis supporting system (10) includes a diagnosis data obtaining unit (20) that obtains diagnosis data in which a movement parameter reflecting a movement speed of each component in separating a sample collected from a test subject into plural components with a chip (12) and a character of each component is in correspondence, a parameter storing unit (34) that stores the movement parameter of a characteristic component showing a state of suffering from a specific disease in correspondence with the disease, a relationship data storing unit (35) that stores relationship data showing a relationship between the character of the characteristic component and a possibility of suffering from a specific disease, a detecting unit (21) that detects the characteristic component from the diagnosis data based on the movement parameter of the characteristic component and the movement parameter of the diagnosis data by making reference to the parameter storing unit (34), and an inference processing unit (22) that infer
    Type: Application
    Filed: October 31, 2008
    Publication date: March 12, 2009
    Applicant: NEC Corporation
    Inventors: Wataru HATTORI, Toru Sano, Masakazu Baba, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Hiroko Someya
  • Publication number: 20080070283
    Abstract: A reaction apparatus (10) includes a substrate (12) and a plurality of columnar members (14) formed on the substrate (12). Oligonucleotides for immobilization (16) having sequences complementary to sequences of both ends of a starting template DNA (18) is adhered on the surfaces of the substrate (12) and the columnar members (14). The starting template DNA (18) can be immobilized over the adjacent columnar members (14) by introducing the starting template DNA (18) under the elongated condition. PCR is conducted in such condition.
    Type: Application
    Filed: September 12, 2007
    Publication date: March 20, 2008
    Inventors: Toru Sano, Masakazu Baba, Kazuhiro Ilda, Hisao Kawaura, Noriyuki Iguchi, Wataru Hattori, Hiroko Someya
  • Publication number: 20080023132
    Abstract: Provided is a pressure-sensitive adhesive for an optically functional film which can carry out adhesion with a good durability in adhesion of an optically functional film such as adhesion of a polarizing plate, particularly a polarizing plate integrated with a viewing angle expanding film and the like with a liquid crystal cell, adhesion of a polarizing plate with a retardation film, adhesion of a retardation film with a retardation film and adhesion of a retardation film with a liquid crystal cell and which has the characteristics that a liquid crystal display obtained therefrom is less liable to cause light leakage even under the environment of high temperature and high humidity and that static electricity is less liable to be produced when peeling off a release film from a pressure-sensitive adhesive layer. The pressure-sensitive adhesive for applying an optically functional film comprises a pressure-sensitive adhesive resin and an antistatic agent, wherein a storage elastic modulus (G?) at 23° C. is 0.
    Type: Application
    Filed: July 16, 2007
    Publication date: January 31, 2008
    Applicant: LINTEC CORPORATION
    Inventors: Toru SANO, Koichi Nagamoto, Kentaro Kusama
  • Patent number: 7274016
    Abstract: A liquid sample (104) introduced in a main flow passage (101) is held in a dam portion (105), and a trigger liquid (106) is filled in a trigger flow passage (102). In this state, the trigger liquid (106) is further introduced at desired timing into the trigger flow passage (102) so that the front end portion of the level of the trigger liquid (106) is advanced and the front end portion is brought to be into contact with the dam portion (105). This causes the liquid sample (104) to move to the right (downstream side) in the figure, resulting in the liquid sample (104) flowing out to the downstream side of the main flow passage (101). This means that the trigger liquid (106) provides priming to realize a liquid switch.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: September 25, 2007
    Assignee: NEC Corporation
    Inventors: Kazuhiro Iida, Masakazu Baba, Hisao Kawaura, Toru Sano, Noriyuki Iguchi, Hiroko Someya, Wataru Hattori, Minoru Asogawa
  • Publication number: 20070102362
    Abstract: In a chip (215), an inlet (217), a main channel (221), a separation region (218), and dispensing channels (222) are formed on a substrate (216). It is structured such that a plurality of the dispensing channels (222) are communicated with the main channel (221), and detection reservoirs (223) are communicated with the respective dispensing channels (222).
    Type: Application
    Filed: September 1, 2004
    Publication date: May 10, 2007
    Inventors: Kazuhiro Iida, Hisao Kawaura, Toru Sano
  • Publication number: 20070048179
    Abstract: A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).
    Type: Application
    Filed: September 13, 2004
    Publication date: March 1, 2007
    Inventors: Machiko Fujita, Toru Sano, Kazuhiro Iida, Hisao Kawaura, Wataru Hattori, Masakazu Baba, Noriyuki Iguchi
  • Publication number: 20070026456
    Abstract: A biomolecule is analyzed with high accuracy. A biomolecule is analyzed with high likelihood. A biomolecule as an analysis subject is modified with a marker binding or adsorbing to only its specific portion (S101). Next, the biomolecule modified with the marker is developed on a base plate (S102). The arrangement of the biomolecule on the base plate is detected using a marker (S103). Then, scanning is performed along the shape of the biomolecule present on the detected position (S104). The biomolecule is analyzed based on an information relating to the shape or arrangement of the biomolecule obtained by scanning or an information relating to the arrangement of the marker on the biomolecule (S105).
    Type: Application
    Filed: September 2, 2004
    Publication date: February 1, 2007
    Applicant: NEC CORPORATION
    Inventors: Kenichi Kamijo, Hisao Kawaura, Toru Sano, Yo Tabuse, Hirotaka Minagawa, Kenji Miyazaki
  • Publication number: 20060214101
    Abstract: After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separated in the channel. The ionized fraction is detected by a mass spectrometry unit (363) and analyzed by an analytical result analyzing unit (371). The analytical result is stored in a memory (369) while associated with position information in a driver control unit (367) and information on laser beam irradiation condition in a laser control unit (373), and the analytical result is imaged by an imaging unit (375). The imaged analytical result is displayed on a display (377).
    Type: Application
    Filed: March 15, 2004
    Publication date: September 28, 2006
    Inventors: Katsutoshi Takahashi, Kazuhiro Iida, Masakazu Baba, Noriyuki Iguchi, Toru Sano, Hisao Kawaura, Toshitsugu Sakamoto, Wataru Hattori, Hiroko Someya
  • Publication number: 20060210985
    Abstract: A reaction apparatus (10) includes a substrate (12) and a plurality of columnar members (14) formed on the substrate (12). Oligonucleotides for immobilization (16) having sequences complementary to sequences of both ends of a starting template DNA (18) is adhered on the surfaces of the substrate (12) and the columnar members (14). The starting template DNA (18) can be immobilized over the adjacent columnar members (14) by introducing the starting template DNA (18) under the elongated condition. PCR is conducted in such condition.
    Type: Application
    Filed: March 17, 2004
    Publication date: September 21, 2006
    Inventors: Toru Sano, Masakazu Baba, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Wataru Hattori, Hiroko Someya
  • Publication number: 20060206010
    Abstract: A diagnostic support system includes a mobile terminal (14) and an analytical center (20), which are connected to each other through a network, and judges a morbidity possibility that a user holding the mobile terminal (14) is suffering from a disease. The analytical center (20) includes a data obtaining unit (26) which obtains symptom data representing the symptom of the user from the mobile terminal (14) in correspondence with a position at which and a date on which the symptom data was made, a morbidity possibility calculation unit (36) which judges the morbidity possibility that the user is suffering from the disease, based on the symptom data and a reference parameter representing the feature generated in sufferers of the disease, and an estimation processing unit (34) which estimates the existing states of sufferers of the disease for each area and in each period, based on morbidity possibilities of a plurality of users, and corresponding positions and dates.
    Type: Application
    Filed: May 7, 2004
    Publication date: September 14, 2006
    Inventors: Kazuhiro Iida, Toru Sano, Wataru Hattori
  • Publication number: 20060177350
    Abstract: A sample-carrier complex (119) is introduced into a sample introducing portion (107), and the sample-carrier complex (119) is moved and deposited on a damming portion (111). The damming portion (111) is heated at a stage in which the predetermined amount of sample-carrier complex (119) is deposited on the damming portion (111). A temperature is increased to a predetermined temperature to break down the sample-carrier complex (119) into a sample (121) and a carrier (123). A voltage is applied between the sample introducing portion (107) and a sample recovery portion (109) to cause the sample (121) to pass through a gap between columnar bodies (115) and move into a second channel (106) to perform predetermined separation and analysis or recovery operation.
    Type: Application
    Filed: March 19, 2004
    Publication date: August 10, 2006
    Inventors: Toru Sano, Masakazu Baba, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Wataru Hattori, Hiroko Someya
  • Publication number: 20060172436
    Abstract: A diagnosis supporting system (10) includes a diagnosis data obtaining unit (20) that obtains diagnosis data in which a movement parameter reflecting a movement speed of each component in separating a sample collected from a test subject into plural components with a chip (12) and a character of each component is in correspondence, a parameter storing unit (34) that stores the movement parameter of a characteristic component showing a state of suffering from a specific disease in correspondence with the disease, a relationship data storing unit (35) that stores relationship data showing a relationship between the character of the characteristic component and a possibility of suffering from a specific disease, a detecting unit (21) that detects the characteristic component from the diagnosis data based on the movement parameter of the characteristic component and the movement parameter of the diagnosis data by making reference to the parameter storing unit (34), and an inference processing unit (22) that infer
    Type: Application
    Filed: February 26, 2004
    Publication date: August 3, 2006
    Inventors: Wataru Hattori, Toru Sano, Masakazu Baba, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Hiroko Someya
  • Publication number: 20060102836
    Abstract: A liquid sample (104) introduced in a main flow passage (101) is held in a dam portion (105), and a trigger liquid (106) is filled in a trigger flow passage (102). In this state, the trigger liquid (106) is further introduced at desired timing into the trigger flow passage (102) so that the front end portion of the level of the trigger liquid (106) is advanced and the front end portion is brought to be into contact with the dam portion (105). This causes the liquid sample (104) to move to the right (downstream side) in the figure, resulting in the liquid sample (104) flowing out to the downstream side of the main flow passage (101). This means that the trigger liquid (106) provides priming to realize a liquid switch.
    Type: Application
    Filed: December 2, 2003
    Publication date: May 18, 2006
    Applicant: NEC Corporation
    Inventors: Kazuhiro Iida, Masakazu Baba, Hisao Kawaura, Toru Sano, Noriyuki Iguchi, Hiroko Someya, Wataru Hattori, Minoru Asogawa
  • Publication number: 20060070951
    Abstract: A particular component in a sample is recovered in a high concentration and solvent-replaced. A separator 100 is placed on a microchip and includes a channel 112 for flowing the particular component. The channel 112 includes a sample feeding channel 300 as well as a filtrate discharge channel 302 and a sample recovering part 308 which are branched from the sample feeding channel 300. There is formed a filter 304 for preventing passage of the particular component, at the inlet of the filtrate discharge channel 302 from the sample feeding channel 300. Furthermore, there is formed a damming area (hydrophobic area) 306 for preventing entering of a liquid sample while allowing for passage of the liquid sample by applying an external force equal to or larger than a given level, at the inlet of the sample recovering part 308 from the sample feeding channel 300.
    Type: Application
    Filed: November 28, 2003
    Publication date: April 6, 2006
    Inventors: Masakazu Baba, Toru Sano, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Wataru Hattori, Hiroko Someya, Minoru Asogawa
  • Publication number: 20060063273
    Abstract: Individual components are separated with a high concentration and accurately, from a sample containing components-to-be-separated. The separation apparatus includes a channel through which a sample containing components-to-be-separated moves; and gateway portions partitioning the separation channel into a plurality of compartments. The separation apparatus further includes an external force imposing unit, which imposes external force to the components-to-be-separated so as to allow them to move through the channel. The external force imposing unit is configured so as to alternately repeatedly execute a first external force imposing pattern by which the external force is imposed in the forward direction of the channel, and a second external force imposing pattern by which the external force is imposed in the direction opposite to the forward direction along the channel. This makes it possible to fractionate the components-to-be-separated into any of the compartments.
    Type: Application
    Filed: December 1, 2003
    Publication date: March 23, 2006
    Applicant: NEC CORPORATION
    Inventors: Minoru Asogawa, Masakazu Baba, Hisao Kawaura, Toru Sano, Kazuhiro Iida, Noriyuki Iguchi, Hiroko Someya
  • Publication number: 20060043284
    Abstract: A sample reservoir (205) in which a sample (213) is introduced is sealed by a septum (207). On piercing the septum (207) by an injection needle, the sample reservoir (205) is communicated with the outer atmosphere, and then the sample (213) is delivered from the channel 203 to the water absorbing portion (209).
    Type: Application
    Filed: November 28, 2003
    Publication date: March 2, 2006
    Applicant: NEC CORPORATION
    Inventors: Masakazu Baba, Toru Sano, Kazuhiro Iida, Hisao Kawaura, Noriyuki Iguchi, Wataru Hattori, Hiroko Someya, Minoru Asogawa